Fondaparinux sodium CAS 114870-03-0 API

Takaitaccen Bayani:

Sunan Chemical: Fondaparinux sodium

Saukewa: 114870-03

Bayyanar: Fari zuwa Kashe-fari foda

Binciken: 95.0% ~ 103.0%

Antithrombotic Anticoagulant, Factor Xa Inhibitor

Tuntuɓi: Dr. Alvin Huang

Wayar hannu/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Bayani:

Ƙarfafawa tare da Babban Tsafta da Ƙarfin Ƙarfi
Sunan Chemical: Fondaparinux sodium
Saukewa: 114870-03
Antithrombotic Anticoagulant, Factor Xa Inhibitor
API High Quality, Kasuwancin Kasuwanci

Abubuwan Sinadarai:

Sunan Sinadari	Fondaparinux sodium
Lambar CAS	114870-03-0
Lambar CAT	RF-API84
Matsayin Hannun jari	A Hannun jari, Ma'aunin Samfuran Har zuwa Daruruwan Kilogram
Tsarin kwayoyin halitta	C31H43N3O49S8.10Na
Nauyin Kwayoyin Halitta	1728.08
Alamar	Ruifu Chemical

Ƙayyadaddun bayanai:

Abu	Ƙayyadaddun bayanai
Bayyanar	Fari zuwa Kashe-Farin Foda
Hanyar Assay / Analysis	95.0% ~ 103.0% (a busasshen tushe)
Solubility	Soluble a cikin Ruwa, 2.0M Sodium Chloride da 0.5M Sodium Hydroxide da Insoluble a cikin Ethanol
Bayanan Bayani na 13C-NMR	Ya kamata a lura da resonances na Fondaparinux Sodium a 58.2, 29.5, 60.5, 60.8, 68.9, 69.2, 69.6, 98.9, 100.4, 101.1, 102.4, 103.9, 176.7mpp da 176.7mpp.Canje-canjen sinadarai na waɗannan sigina ba su bambanta da fiye da ± 0.3ppm sauran sigina na tsayi masu tsayi da canjin sinadarai, wanda aka danganta da Fondaparinux Sodium, wataƙila ana iya gani tsakanin 58.0 ~ 80.5 ppm da 98.7 ~ 104.5ppm
Bayanin HPLC	Lokacin riƙewa na babban kololuwar samfurin samfurin ya dace da na daidaitaccen bayani
Bayanin AAS	Sodium yakamata ya sami halayen halayen halayen a 330.2nm ƙarƙashin ƙaddarar sodium
pH	6.0-8.0
Sodium (Na)	11.5% ~ 15.0% (Lissafta akan anhydrous da kaushi kyauta)
Sulfate kyauta	≤0.30%
Ragowar Chloride	≤1.00%
Abubuwa masu alaƙa
Najasa A	≤0.80%
Rashin tsarki B	≤0.60%
Daya Sauran Rashin Tsabta	≤0.30%
Jimlar ƙazanta	≤2.00%
Ragowar Magani
Methanol	≤3000ppm
Ethanol	≤5000ppm
Ethyl acetate	≤5000ppm
DMF	≤880ppm
Methylbenzene	≤890ppm
Pyridine	≤50ppm
Abubuwan Ruwa (KF)	≤15.0%
Bacterial Endotoxins	≤3.3EU/mg
Iyakar Microbial	Jimlar adadin ƙwayoyin cuta ≤100cfu/g
Matsayin Gwaji	Matsayin Kasuwanci;Amurka Pharmacopoeia (USP) Standard
Amfani	API, Antithrombotic Anticoagulant, Factor Xa Inhibitor

Kunshin & Ajiya:

Kunshin: Bottle, Aluminum tsare jakar, Kwali drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.

Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.

Amfani:

FAQ:

Aikace-aikace:

Fondaparinux Sodium (CAS 114870-03-0) shine farkon sabon aji na antithrombotic anticoagulant sinadarai masu alaƙa da ƙananan nauyin heparins (LMWH).Fondaparinux sodium shine factor Xa inhibitor don samar da babban haɗin haɗin gwiwa don anti-coagulant factor antithrombin III (ATIII).Fondaparinux sodium dauri a wannan rukunin yanar gizon yana ƙarfafa tasirin hanawa na halitta na ATIII akan factor Xa ta hanyar kusan 300, wanda ke haifar da hana haɓakar thrombin.GlaxoSmithKline ne ke tallata shi.Wani nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i) wanda Alchemia ya haɓaka a cikin Amurka ta Dr. Reddy's Laboratories.Fondaparinux sodium an fara gabatar da shi a cikin Amurka don rigakafin thrombosis mai zurfi wanda zai iya haifar da kumburin huhu bayan babban tiyatar kasusuwa.Wannan kwayar halittar gaba daya ta roba kwafin jerin heparin pentasaccharide ne, mafi guntu guntu iya haifar da hanawar antithrombin lllmediated na factor Xa ta haka yana hana tsarawar thrombin ba tare da aikin antithrombin ba.