Fulvestrant (ICI 182780) CAS 129453-61-8 API Factory High Quality Featured Image

Fulvestrant (ICI 182780) CAS 129453-61-8 API High Quality Factory

Takaitaccen Bayani:

Suna: Fulvestrant (ICI 182780)

Saukewa: 129453-61-8

Bayyanar: Fari zuwa Kashe-Farin Crystalline Foda

Assay: 97.0% ~ 102.0% (a kan busassun tushen)

Ana amfani da Fulvestrant a cikin maganin ciwon daji na ci gaba na hormone-m a cikin matan da suka shude.

API High Quality, Kasuwancin Kasuwanci

Inquiry: alvin@ruifuchem.com

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Bayani:

Samar da Mai ƙira tare da Tsaftataccen Tsafta da Tsayayyen inganci
Suna: Fulvestrant
Saukewa: 129453-61-8
Ana amfani da Fulvestrant a cikin maganin ciwon daji na ci gaba na hormone-m a cikin matan da suka shude.
API High Quality, Kasuwancin Kasuwanci

Abubuwan Sinadarai:

Sunan Sinadari	Fulvestrant
Makamantu	(7α,17β) -7- [9-[(4,4,5,5,5-Pentafluorpentyl) sulfinyl] nonyl] estra-1,3,5 (10) -trien-3,17-diol;Farashin 182780
Lambar CAS	129453-61-8
Lambar CAT	RF-API81
Matsayin Hannun jari	A Hannun jari, Ma'aunin Samfuran Har zuwa Daruruwan Kilogram
Tsarin kwayoyin halitta	Saukewa: C32H47F5O3S
Nauyin Kwayoyin Halitta	606.77
Matsayin narkewa	104.0 ~ 106.0 ℃
Solubility	Mai narkewa a cikin methanol, ethanol;Mara narkewa a cikin Ruwa
Alamar	Ruifu Chemical

Ƙayyadaddun bayanai:

Abu	Ƙayyadaddun bayanai
Bayyanar	Fari zuwa Kashe-White Crystalline Foda
Ganewa	By IR, HPLC
Takamaiman Juyawar gani	+108.0° zuwa +115.0°
Asara akan bushewa	≤0.50%
Ragowa akan Ignition	≤0.10%
6-Keto-Fulvestrant	≤0.10%
6,7-Mai cikawa	≤0.10%
Fulvestrant Sulfone	≤0.20%
Fulvestrant Extended	≤0.30%
Fulvestrant Sterol Dimmer	≤0.80%
Duk wani Mutum da Ba a Fahimce shi ba	≤0.10%
Jimlar ƙazanta	≤1.0%
Fulvestrant A	42.0% ~ 48.0%
Fulvestrant B	52.0% ~ 58.0%
DMF	≤620ppm
Karfe masu nauyi	≤10ppm
Assay	97.0% ~ 102.0% (a busasshen tushe)
Adanawa	Ajiye a cikin kwantena masu jure haske da kyau a rufe a cikin firiji a 2 ~ 8 ℃
Matsayin Gwaji	Amurka Pharmacopoeia (USP) Standard
Amfani	Estrogen Receptor antagonist

Kunshin & Ajiya:

Kunshin: Bottle, Aluminum tsare jakar, Kwali drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.

Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.

Amfani:

FAQ:

Aikace-aikace:

Fulvestrant (ICI-182780) CAS 129453-61-8, maganin allurar tsoka ne wanda kamfanin AstraZeneca ya kirkira kuma ana amfani dashi a cikin maganin ciwon daji na ci gaba na hormone a cikin matan postmenopausal.Fulvestrant shine kawai maganin antiestrogen wanda za'a iya amfani dashi ko'ina a asibiti bayan rashin nasarar maganin tamoxifen.Wannan miyagun ƙwayoyi wani nau'i ne na maganin endocrin, don haka ba zai haifar da wani mummunan tasiri da aka saba gani a chemotherapy ba, yana ba shi kyakkyawar yarda da haƙuri.Gwaje-gwaje na asibiti da yawa sun gano cewa 250mg Fulvestrant yana da tasiri kuma yana da aminci a matsayin layi na biyu na maganin ciwon nono mai ci gaba.Fulvestrant shine mai karɓan Estrogen na roba (ER) mai adawa da IC50 na 0.94 nM a cikin gwajin da ba shi da salula.Fulvestrant kuma yana haifar da autophagy da apoptosis kuma yana da aikin antitumor.