Gefitinib CAS 184475-35-2 Tsafta > 99.5% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. shine babban kamfani na Gefitinib (CAS: 184475-35-2) tare da inganci.Ruifu Chemical na iya samar da isar da saƙo na duniya, farashi mai gasa, kyakkyawan sabis, ƙanana da adadi mai yawa akwai.Sayi Gefitinib da masu tsaka-tsaki,Please contact: alvin@ruifuchem.com
| Sunan Sinadari | Gefitinib |
| Makamantu | Gefitinib Free Base;Iressa;ZD1839;ZD-1839;N- (3-Chloro-4-Fluorophenyl) -7-Methoxy-6- (3-Morpholinopropoxy) quinazolin-4-Amine;N- (3-Chloro-4-Fluorophenyl) -7-Methoxy-6-[3- (4-Morpholinyl) wakili]-4-Quinazolinamine |
| Matsayin Hannun jari | A Stock, Kasuwancin Kasuwanci |
| Lambar CAS | 184475-35-2 |
| Tsarin kwayoyin halitta | Saukewa: C22H24ClFN4O3 |
| Nauyin Kwayoyin Halitta | 446.91 g/mol |
| Matsayin narkewa | 194.0 zuwa 198.0 ℃ |
| Yawan yawa | 1.322± 0.06 g/cm3 |
| Ruwan Solubility | Mara narkewa a cikin Ruwa |
| Solubility | Mai narkewa a cikin DMSO |
| Adana Yanayin. | Yanayin Daki |
| Jirgin ruwa | Na yanayi |
| COA & MSDS | Akwai |
| Asalin | Shanghai, China |
| Alamar | Ruifu Chemical |
| Abubuwa | Ka'idojin dubawa | Sakamako |
| Bayyanar | Fari zuwa Kashe-Farin Foda | Ya bi |
| Asara akan bushewa | <0.50% | 0.13% |
| Ragowa akan Ignition | <0.20% | 0.06% |
| Tsaftace Guda Daya | <0.10% | 0.09% |
| Jimlar ƙazanta | <0.50% | 0.20% |
| Karfe masu nauyi (Pb) | ≤10ppm | <10ppm |
| Tsarkake / Hanyar Bincike | > 99.5% (HPLC) | 99.80% |
| Infrared Spectrum | Daidai da Tsarin | Ya bi |
| 1H NMR Spectrum | Daidai da Tsarin | Ya bi |
| Kammalawa | An gwada samfurin kuma ya dace da ƙayyadaddun da aka bayar | |
Kunshin:Fluorinated Bottle, Aluminum tsare jakar, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye akwati sosai kuma a adana a cikin sanyi, busasshe kuma mai cike da iska daga abubuwan da ba su dace ba.Kare daga haske da danshi.
Jirgin ruwa:Isar da shi zuwa duniya ta iska, ta FedEx / DHL Express.Bayar da isarwa cikin sauri kuma abin dogaro.
Ba don amfani a cikin mutane ba.Ba don amfani ba a cikin bincike ko warkewa.Don binciken in vitro amfani kawai.
Babu ɗaya daga cikin samfuran da za a ba wa ƙasashen da hakan zai iya yin rikici da haƙƙin mallaka.Koyaya alhakin ƙarshe yana kan mai siye.
Yadda ake siya?Da fatan za a tuntuɓiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Kwarewar Shekaru 15?Muna da fiye da shekaru 15 na gwaninta a cikin ƙira da fitarwa na matsakaicin matsakaicin magunguna masu inganci ko sinadarai masu kyau.
Manyan Kasuwanni?Sayarwa zuwa kasuwannin cikin gida, Arewacin Amurka, Turai, Indiya, Koriya, Jafananci, Australia, da sauransu.
Fa'idodi?Babban inganci, farashi mai araha, sabis na ƙwararru da tallafin fasaha, bayarwa da sauri.
inganciTabbaci?Tsananin kula da ingancin inganci.Kayan aikin ƙwararru don bincike sun haɗa da NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, gwajin ƙayyadaddun ƙwayoyin cuta, da sauransu.
Misali?Yawancin samfurori suna ba da samfurori kyauta don ƙima mai kyau, farashin jigilar kaya ya kamata a biya ta abokan ciniki.
Binciken Masana'antu?Ma'aikata duba maraba.Da fatan za a yi alƙawari a gaba.
MOQ?Babu MOQ.Karamin tsari abin karɓa ne.
Lokacin Bayarwa? Idan cikin hannun jari, garantin isar da kwana uku.
Sufuri?By Express (FedEx, DHL), ta Air, ta Teku.
Takardu?Bayan sabis na tallace-tallace: COA, MOA, ROS, MSDS, da dai sauransu za a iya ba da su.
Haɗin Kan Al'ada?Zai iya ba da sabis na haɗawa na al'ada don dacewa da buƙatun bincikenku.
Sharuɗɗan Biyan kuɗi?Za a fara aiko da daftari na Proforma bayan tabbatar da oda, an rufe bayanan bankin mu.Biya ta T/T (Telex Transfer), PayPal, Western Union, da dai sauransu.
| Bayanin Tsaro | 24/25 - Guji hulɗa da fata da idanu. |
| HS Code | 293499909 |
Gefitinib (CAS: 184475-35-2) magani ne na musamman na rigakafin ƙwayar cuta wanda AstraZeneca, UK ya haɓaka.Ita ce magani na farko da aka yi niyya na ƙwayoyin cuta don maganin ciwon daji na huhu mara ƙarami.Yana aiki ta hanyar zaɓin hana hanyar watsa sigina na mai karɓar haɓakar haɓakar haɓakar epidermal tyrosine kinase (EGFR-TK).Epidermal girma factor (EGF) shi ne polypeptide tare da dangi na kwayoyin halitta na 6.45 × 103, wanda zai iya haɗuwa tare da mai karɓa na girma na epidermal (EGFR) akan ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta don samar da ilimin halitta.EGFR shine mai karɓar nau'in tyrosine kinase (TK).Lokacin da ya ɗaure zuwa EGF, zai iya inganta kunnawa TK a cikin jikin mai karɓa, wanda ya haifar da autophosphorylation na ragowar tyrosine mai karɓa, samar da ci gaba da rarraba sigina ga sel, haifar da yaduwar kwayar halitta da bambanci.EGFR yana da yawa a cikin kyallen jikin mutum kuma an bayyana shi sosai a cikin ciwace-ciwacen daji.Ta hanyar toshe hanyar siginar EGFR akan tantanin halitta, gefitinib yana hana ci gaban ƙari, metastasis da angiogenesis, kuma yana iya haifar da apoptosis na ƙwayoyin ƙari.A watan Agustan 2002, an fara sayar da gefitinib a Japan a matsayin magani na farko don ciwon daji na huhu mara ƙananan ƙwayoyin cuta a ƙarƙashin sunan kasuwanci Iressa.A cikin Mayu 2003, Hukumar Abinci da Magunguna ta Amurka ta amince da gefitinib a matsayin tsarin monotherapy na layi na uku don marasa lafiya da ke fama da ciwon huhu marasa ƙananan ƙwayoyin cuta waɗanda ba su da tasiri tare da magungunan rigakafin cutar kansa na tushen platinum da chemotherapy na docetaxel.A halin yanzu, Ostiraliya, Japan, Argentina, Singapore da Koriya ta Kudu sun amince da ita don maganin ciwon daji na huhu mara ƙananan ƙwayoyin cuta.A ranar 28 ga Fabrairu, 2005, Hukumar Kula da Abinci da Magunguna ta kasar Sin ta amince da gefitinib don kula da ciwon daji na huhu na cikin gida ko na metastatic (NSCLC) wanda a baya ya sami ilimin chemotherapy.A halin yanzu ba a yarda da shi don amfani azaman jigon layin farko don ci gaba na NSCLC ba.A ranar 1 ga Yuli, 2009, Hukumar Kula da Magunguna ta Turai ta amince da gefitinib bisa hukuma don layin farko, layi na biyu da jiyya na layi na uku na ci gaba a cikin gida ko metastatic marasa ƙananan ƙwayar huhu tare da maye gurbin EGFR a cikin manya.
