Gemcitabine CAS 95058-81-4 Assay 98.0 ~ 102.0%
Shanghai Ruifu Chemical Co., Ltd. shine babban kamfani na Gemcitabine (CAS: 95058-81-4) tare da inganci mai kyau.Ruifu Chemical na iya samar da isar da saƙo na duniya, farashi mai gasa, kyakkyawan sabis, ƙanana da adadi mai yawa akwai.Sayi Gemcitabine,Please contact: alvin@ruifuchem.com
| Sunan Sinadari | Gemcitabine |
| Makamantu | 2'-Deoxy-2',2'-Difluorocytidine;4-Amino-1-[3,3-Difluoro-4-Hydroxy-5- (Hydroxymethyl) oxolan-2-yl] pyrimidin-2-daya;dFDC;Gemzar (Lilly);LY-188011;dFdCyd;DDFC;2',2'-Difluoro-2'-deoxycytidine;2',2'-Difluorodeoxycytidine;Folfugem;GemLip;Gemcel;Gamcitabine |
| Matsayin Hannun jari | A Stock, Ƙarfin Samar da Ton 5 |
| Lambar CAS | 95058-81-4 |
| CAS mai alaƙa | 122111-03-9 |
| Tsarin kwayoyin halitta | Saukewa: C9H11F2N3O4 |
| Nauyin Kwayoyin Halitta | 263.20 g/mol |
| Matsayin narkewa | 217.0 zuwa 222.0 ℃ |
| Yawan yawa | 1.84± 0.10 g/cm3 |
| M | Zafi Sensitive |
| Ruwan Solubility | A zahiri Mara narkewa a cikin Ruwa |
| COA & MSDS | Akwai |
| Asalin | Shanghai, China |
| Alamar | Ruifu Chemical |
| Abubuwa | Ƙayyadaddun bayanai | Sakamako |
| Bayyanar | Fari ko Kusan Farin Lu'ulu'u Foda, Marasa wari | Ya bi |
| Cytosin | ≤0.10% | 0.002% |
| α-Isomer | ≤0.10% | 0.01% |
| Rashin Tsabtace Mutum | ≤0.10% | 0.03% |
| Jimlar ƙazanta | ≤1.00% | 0.10% |
| Ruwa ta Karl Fischer | ≤1.00% | 0.67% |
| Takamaiman Juyawa | +68.0°~+74.0° | +70.5° |
| Karfe masu nauyi | ≤10ppm | <10ppm |
| Ragowa akan Ignition | ≤0.10% | 0.03% |
| Assay (Na HPLC) | 98.0% ~ 102.0% | 99.9% |
| Infrared Spectrum | Daidai da Tsarin | Ya bi |
| 1H NMR Spectrum | Daidai da Tsarin | Ya bi |
| Kammalawa | An gwada samfurin kuma ya dace da ƙayyadaddun da aka bayar | |
Kunshin:Bottle, Aluminum tsare jakar, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye akwati sosai kuma a adana a cikin sanyi, busasshe kuma mai cike da iska daga abubuwan da ba su dace ba.Ka guji fallasa zuwa hasken rana kai tsaye, danshi da zafi mai yawa.
Jirgin ruwa:Isar da shi zuwa duniya ta iska, ta FedEx / DHL Express.Bayar da isarwa cikin sauri kuma abin dogaro.
Yadda ake siya?Da fatan za a tuntuɓiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Kwarewar Shekaru 15?Muna da fiye da shekaru 15 na gwaninta a cikin ƙira da fitarwa na matsakaicin matsakaicin magunguna masu inganci ko sinadarai masu kyau.
Manyan Kasuwanni?Sayarwa zuwa kasuwannin cikin gida, Arewacin Amurka, Turai, Indiya, Koriya, Jafananci, Australia, da sauransu.
Fa'idodi?Babban inganci, farashi mai araha, sabis na ƙwararru da tallafin fasaha, bayarwa da sauri.
inganciTabbaci?Tsananin kula da ingancin inganci.Kayan aikin ƙwararru don bincike sun haɗa da NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, gwajin ƙayyadaddun ƙwayoyin cuta, da sauransu.
Misali?Yawancin samfurori suna ba da samfurori kyauta don ƙima mai kyau, farashin jigilar kaya ya kamata a biya ta abokan ciniki.
Binciken Masana'antu?Ma'aikata duba maraba.Da fatan za a yi alƙawari a gaba.
MOQ?Babu MOQ.Karamin tsari abin karɓa ne.
Lokacin Bayarwa? Idan cikin hannun jari, garantin isar da kwana uku.
Sufuri?By Express (FedEx, DHL), ta Air, ta Teku.
Takardu?Bayan sabis na tallace-tallace: COA, MOA, ROS, MSDS, da dai sauransu za a iya ba da su.
Haɗin Kan Al'ada?Zai iya ba da sabis na haɗawa na al'ada don dacewa da buƙatun bincikenku.
Sharuɗɗan Biyan kuɗi?Za a fara aiko da daftari na Proforma bayan tabbatar da oda, an rufe bayanan bankin mu.Biya ta T/T (Telex Transfer), PayPal, Western Union, da dai sauransu.
Lambobin haɗari R21 - Yana cutar da fata
R36/38 - Iriting ga idanu da fata.
R46 - Yana iya haifar da lalacewar gadon gado
R62 - Haɗari mai yuwuwar rashin haihuwa
R63 - Yiwuwar haɗarin cutar da ɗan da ba a haifa ba
Bayanin Tsaro S25 - Guji lamba tare da idanu.
S26 - Idan ana hulɗa da idanu, kurkura nan da nan da ruwa mai yawa kuma ku nemi shawarar likita.
S36/37 - Sanya tufafin kariya da safar hannu masu dacewa.
S53 - Guji fallasa - sami umarni na musamman kafin amfani.
Lambar 2934999091
Guba LD10 iv a cikin berayen: 200 mg/m2 (Abbruzzese)
Gemcitabine (CAS: 95058-81-4) magani ne na chemotherapy da ake amfani dashi don magance nau'ikan ciwon daji.Wannan ya haɗa da kansar nono, kansar huhu mara ƙarami, kansar pancreatic, kansar mafitsara, da kansar biliary tract.Ana binciken Gemcitabine don amfani da shi a cikin ciwon daji na esophageal, kuma ana amfani da shi ta gwaji a cikin lymphomas da sauran nau'in ciwon daji daban-daban.Gemcitabine ana gudanar da shi ta hanyar hanji, tun da yake an daidaita shi sosai ta hanyar gastrointestinal tract.
Gemcitabine shine analog na nucleotide, wanda ke cikin nau'in anti-metabolism na maganin ciwon daji.Ya fi yin aiki akan lokaci na kira na DNA, wato, lokaci S.A ƙarƙashin wasu sharuɗɗa, zai iya hana lokacin G1 daga ci gaba zuwa lokacin S.Yana da halaye na bakan anticancer, na musamman na tsarin aiki, ƙarancin guba, ba tare da juriya ga sauran magungunan chemotherapy ba kuma ba shi da ma'ana mai ƙarfi.Littafin sinadarai, gemcitabine, yanzu an amince da shi don amfani da shi a cikin ƙasashe sama da 90, wanda ya mai da shi layin farko na maganin kansar huhun huhun da ba ƙananan ƙwayoyin cuta ba da kuma "ma'aunin zinariya" na ciwon daji na pancreatic.
A cikin 1999, CFDA ta amince da gemcitabine don maganin ci gaba na gida ko NSCLC, ci gaba na gida ko ciwon daji na pancreatic;A cikin 2010, CChemicalbookFDA ta amince da gemcitabine a haɗe tare da paclitaxel don maganin unresectable, gida mai maimaitawa ko ciwon daji na nono wanda ya sake dawowa bayan adjuvant/neoadjuvant chemotherapy.
Gemcitabine ne m-bakan antimetabolite da deoxycytidine analogue tare da antineoplastic aiki.Bayan gudanarwa, an canza gemcitabine zuwa cikin metabolites masu aiki difluorodeoxycytidine diphosphate (dFdCDP) da difluorodeoxycytidine triphosphate (dFdCTP) ta hanyar deoxycytidine kinase.dFdCTP yana gasa da deoxycytidine triphosphate (dCTP) kuma an haɗa shi cikin DNA.Wannan yana kulle DNA polymerase ta haka yana haifar da ƙarewar abin rufe fuska yayin kwafin DNA.A gefe guda, dFdCDP yana hana ribonucleotide reductase, don haka yana rage tafkin deoxynucleotide da ake samu don haɗin DNA.Rage ƙaddamar da ƙwaƙwalwar cikin salula na dCTP yana ƙarfafa shigar dFdCTP cikin DNA.
