Glimepiride CAS 93479-97-1 Assay 98.0% ~ 102.0% API Babban Tsabta
Ƙarfafawa tare da Babban Tsafta da Ƙarfin Ƙarfi
Sunan Sinadari: Glimepiride
Saukewa: 93479-1
Glimepiride a cikin maganin Noninsulin-Dogara Nau'in Ciwon sukari na 2
API High Quality, Kasuwancin Kasuwanci
Sunan Sinadari | Glimepiride |
Makamantu | Amaryl |
Lambar CAS | 93479-97-1 |
Lambar CAT | RF-API24 |
Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
Tsarin kwayoyin halitta | Saukewa: C24H34N4O5S |
Nauyin Kwayoyin Halitta | 490.62 |
Matsayin narkewa | 212.2 ~ 214.5 ℃ |
Yanayin jigilar kaya | Karkashin Zazzabi |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Fari ko Kusan Farin Foda |
Ganewa | IR (mai kama da Standard) |
Abubuwa masu alaƙa | |
Cis-Isomer (A) | ≤0.80% |
Sulfonamide (B) | ≤0.40% |
Uretane (C) | ≤0.10% |
3-Isomer (D) | ≤0.20% |
Duk Wani Najasa | ≤0.10% |
Jimlar ƙazanta | ≤0.50% |
Asara akan bushewa | ≤0.50% |
Ragowa akan Ignition | ≤0.10% |
Karfe masu nauyi | ≤0.001% |
Assay | 98.0% ~ 102.0% |
Matsayin Gwaji | Turai Pharmacopeia (EP);Amurka Pharmacopoeia (USP) |
Amfani | Sinadarin Magunguna Mai Aiki (API) |
Kunshin: Bottle, Aluminum tsare jakar, Kwali drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.
Shanghai Ruifu Chemical Co., Ltd. shine babban masana'anta kuma mai samar da Glimepiride (CAS: 93479-97-1) tare da inganci mai inganci, kayan aikin magunguna (API).Glimepiride magani ne na ciwon sukari wanda ke taimakawa sarrafa matakan sukari na jini.Glimepiride wani dogon aiki ne, sulfonylurea na ƙarni na uku tare da aikin hypoglycemic.
Glimepiride (sunan kasuwanci na asali Amaryl) magani ne na sulfonylurea na maganin ciwon sukari na matsakaici-zuwa-dogon aiki.Kamar duk sulfonylureas, glimepiride yana aiki azaman sirrin insulin.Yana rage sukarin jini ta hanyar ƙarfafa sakin insulin daga ƙwayoyin beta masu aiki na pancreatic kuma ta hanyar haɓaka halayen kyallen takarda zuwa insulin.Wataƙila Glimepiride yana ɗaure ga masu karɓar tashar potassium mai rahusa ATP akan saman tantanin halitta na pancreatic, yana rage tasirin potassium kuma yana haifar da depolarization na membrane.Depolarization na membrane yana ƙarfafa kwararar ion calcium ta hanyar tashoshi na calcium masu ƙarfin lantarki.Wannan karuwa a cikin ƙwayoyin calcium ion maida hankali yana haifar da sakin insulin.Ana amfani da Glimepiride musamman don kula da marasa lafiya da ke da nau'in ciwon sukari na 2 kuma yana iya rage yuwuwar wani zai iya haifar da rikice-rikice na nau'in ciwon sukari na 2.FDA ta amince da maganin a cikin 1995 kuma Sanofi-Aventis ne ya kera shi.Ana iya amfani da shi tare da ingantaccen tsarin abinci da motsa jiki kuma ana iya amfani da shi kaɗai ko tare da wasu magungunan antidiabetic idan an buƙata.Ana iya amfani da Glimepiride ko dai a matsayin monotherapy ko a hade tare da insulin.