Ibrutinib Deacryloylpiperidine CAS 330786-24-8 Tsafta > 99.0% (HPLC)
Sunan Sinadari | 3- (4-Phenoxyphenyl) -1H-pyrazolo [3,4-d] pyrimidin-4-amin |
Makamantu | Ibrutinib tsaka-tsakin N-2;Ibrutinib Deacryloylpiperidine;Ibrutinib rashin tsarki 8;5- (4-Phenoxyphenyl) -7H-pyrrolo [2,3-d] pyrimidin-4-ylamine;IBT4A;Ibrutinib N-Despiperidinyl rashin tsarki |
Lambar CAS | 330786-24-8 |
Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
Tsarin kwayoyin halitta | Saukewa: C17H13N5O |
Nauyin Kwayoyin Halitta | 303.32 |
Matsayin narkewa | > 262 ℃ (Dec.) |
Yawan yawa | 1.380± 0.06 g/cm3 |
Matsayin Hazard | 6.1;Guba |
Rukunin tattarawa | III |
COA & MSDS | Akwai |
Asalin | Shanghai, China |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Kashe-White zuwa Khaki Foda |
Ganewa | HNMR, LC-MS |
Tsarkake / Hanyar Bincike | > 99.0% (HPLC) |
Asara akan bushewa | <1.00% |
Single Max.Rashin tsarki | <1.00% |
Jimlar ƙazanta | <1.00% |
Karfe masu nauyi (kamar Pb) | <20ppm |
Matsayin Gwaji | Matsayin Kasuwanci |
Amfani | Matsakaicin Ibrutinib (CAS: 936563-96-1) |
Kunshin: Bottle, Aluminum tsare jakar, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi.
3- (4-Phenoxyphenyl) -1H-pyrazolo [3,4-d] pyrimidin-4-amine (CAS: 330786-24-8) shine tsaka-tsaki na roba mai amfani a cikin kira na Ibrutinib (CAS: 936563-96-1). ).Ibrutinib wani nau'i ne na mai hana Bruton tyrosine kinase (BTK), ana iya amfani dashi don maganin cutar sankarar lymphocytic na kullum (CLL) da lymphoma na mantle cell (MCL).MCL da CLL na cikin ƙwayoyin lymphoma na B-cell ba Hodgkin ba, wanda ke da wuyar warkewa kuma yana da sauƙin maimaitawa.Maganin rigakafi na gama gari ba shi da niyya, sau da yawa yana faruwa 3 ko 4 munanan halayen.Ibrutinib da B lymphocytes na iya yin niyya tare da BTK wanda ya zama dole don samuwar, bambance-bambance, da watsa bayanai, hana ayyukan BTK ba tare da juyewa ba, kuma yana hana yaduwar ƙwayar ƙwayar cuta da rayuwa yadda ya kamata.Ibrutinib zai iya zama da sauri a sha bayan gudanarwa ta baki, a lokacin 1 ~ 2h ya kai matsakaicin maida hankali na jini, mummunan halayen na ɗaya ko biyu, sabili da haka, Ibrutinib zai zama sabon zaɓi na jiyya na CLL da MCL.