N- (2-Methyl-5-nitrophenyl) -4- (pyridin-3-yl) pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate High Tsabta
Samar da Kasuwancin Imatinib Mesylate da Matsakaici masu alaƙa:
Imatinib Mesylate CAS: 220127-57-1
N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl) pyrimidin-2-amine CAS: 152460-09-8
N- (5-Amino-2-methylphenyl) -4- (3-pyridyl) -2-pyrimidinea CAS: 152460-10-1
4-[(4-Methylpiperazin-1-yl) methyl] benzoic acid dihydrochloride CAS: 106261-49-8
Sunan Sinadari | N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl) pyrimidin-2-amine |
Makamantu | Imatinib Mesylate Intermediate;2- (2-Methyl-5-nitroanilino) -4- (3-pyridyl) pyrimidine |
Lambar CAS | 152460-09-8 |
Lambar CAT | Saukewa: RF-PI228 |
Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
Tsarin kwayoyin halitta | Saukewa: C16H13N5O2 |
Nauyin Kwayoyin Halitta | 307.31 |
Matsayin narkewa | 188.0 ~ 193.0 ℃ |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Rawaya Ko Kusan Ruwan Foda |
Tsafta | ≥98.0% (HPLC) |
Danshi (KF) | ≤0.50% |
Jimlar ƙazanta | ≤2.0% |
Matsakaicin Tsabtace Guda Daya | ≤1.0% |
Ragowa akan kunnawa | ≤0.50% |
Karfe masu nauyi | ≤20ppm |
Matsayin Gwaji | Matsayin Kasuwanci |
Amfani | Matsakaicin Imatinib Mesylate (CAS: 220127-57-1) |
Kunshin: Bottle, Aluminum tsare jakar, Kwali drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.
Shanghai Ruifu Chemical Co., Ltd. shine babban masana'anta kuma mai samar da N- (2-Methyl-5-nitrophenyl) -4- (pyridin-3-yl) pyrimidin-2-amine (CAS: 152460-09-8) tare da high quality.Matsakaici ne yawanci a cikin haɗin Imatinib Mesylate (CAS: 220127-57-1).
Imatinib Mesylate karamin kwayoyin halitta ne wanda ke hana c-Abl protein-tyrosine kinase, Musamman musamman ga BCR-ABL, enzyme da ke hade da cutar sankarar jini na myelogenous (CML) da wasu nau'i na cutar sankarar lymphoblastic mai tsanani (ALL).Wani lamari mai canzawa tsakanin chromosomes 9 da 22 yana haifar da chromosome na Philadelphia, wanda sannan ya samar da furotin Bcr-Abl fusion tare da aikin kinase mai banƙyama wanda ke inganta yaduwar kwayar halitta.Imatinib Mesylate yana ɗaure wannan mahimmancin kinase, yana dakatar da haɓakar CML.An ƙara nuna Imatinib Mesylate don hana PDGFR da tyrosine kinases masu alaƙa da c-Kit.An yi amfani da nau'ikan da ke ɗauke da Imatinib Mesylate don magance cututtukan daji daban-daban.