Indapamide CAS 26807-65-8 Tsarkake ≥99.5% (HPLC) API EP Matsayin Ma'auni Mai Kyau
Shanghai Ruifu Chemical Co., Ltd. shine babban masana'anta kuma mai samar da Indapamide da masu tsaka-tsaki masu alaƙa da inganci.
Bayani na CAS 26807-65-8
2-Methylindoline CAS 6872-06-6
1-Amino-2-Methylindoline Hydrochloride CAS 102789-79-7
Sunan Sinadari | Indapamide |
Makamantu | N- (4-Chloro-3-Sulfamoylbenzamido) -2-Methylindoline |
Lambar CAS | 26807-65-8 |
Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
Tsarin kwayoyin halitta | Saukewa: C16H16ClN3O3S |
Nauyin Kwayoyin Halitta | 365.83 |
Matsayin narkewa | 160.0 ~ 162.0 ℃ |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Fari ko Kusan Farin Crystalline Foda |
Solubility | Haƙiƙa Ba Mai Narkewa Cikin Ruwa;Mai narkewa a cikin Ethanol |
Identification A | ultraviolet da kuma Bayyanuwa sha Spectrophotometry |
Identity B | Infrared Absorption Spectrophotometry |
Gano C | Chromatography na bakin ciki |
Juyawar gani | -0.80°~ +0.80° (C=5, C2H5OH) |
Ruwa (EP 2.5.12) | <3.00% |
Sulphated Ash (EP 2.4.14) | <0.10% |
Karfe masu nauyi (EP 2.4.8) | <10ppm |
Abubuwa masu alaƙa | |
Rashin tsarki B | <0.30% |
Tsaftar da Ba a bayyana ba | <0.10% |
Jimlar ƙazanta | <0.50% |
Tsarkake / Hanyar Bincike | > 99.5% (HPLC) |
Matsayin Gwaji | EP Standard |
Amfani | API;Antihypertensive da Diuretic |
Kunshin: Bottle, Aluminum tsare jakar, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi.
Indapamide (CAS: 26807-65-8) antihypertensive ne kuma diuretic.Ta hanyar hana Na + reabsorption a ƙarshen kusancin tubules na distal conflexion, yana haifar da tasirin diuretic kuma yana toshe kwararar Ca2+.Yana da babban zaɓi ga tsoka mai santsi na jijiyoyin jini, yana faɗaɗa ƙananan tasoshin kuma yana haifar da tasirin hypotensive.Amma tasiri akan jijiyoyi santsi mai ƙarfi yana da ƙarfi diuretic sakamako, a ƙasa da diuretic allurai na iya sauka ƙasa, mafi girma allurai nuna diuretic sakamako, amma babu thiazide diuretic shortcomings, wato ba haifar da orthostatic hypotension, ja ruwa da kuma nuna tachycardia, a kan jini hoto, metabolism na jini. mai, sukari da aikin koda kuma ba su da wani tasiri mai mahimmanci, maganin warkewa na bugun zuciya, fitarwar zuciya, babu wani gagarumin canje-canje a cikin electrocardiogram (ecg) sun kasance Ba shi da wani tasiri a kan tsarin juyayi na tsakiya da kuma jijiyar kai tsaye.Gudanar da baki na littafin sinadarai na 2 ~ 3 H ya haifar da tasirin hypotensive, wanda aka kiyaye har tsawon awanni 24.Diuretic sakamako ya bayyana a 3h kuma ya kai iyakar tasirinsa a 4 ~ 6h.Indapamide ya dace da hauhawar jini mai sauƙi da matsakaici na farko, Hakanan ana iya amfani dashi don cututtukan zuciya na rikice-rikice ta hanyar riƙewar sodium ruwa, tare da gazawar koda kuma ana amfani da su ga marasa lafiya da hauhawar jini, ciwon sukari, hyperlipidemia, yin amfani da tasirin antihypertensive yana da ban mamaki.