Irbesartan CAS 138402-11-6 Tsarkake>99.0% (HPLC) API Factory Antihypertensive
Samar da Maƙera, Babban Tsafta, Samar da Kasuwanci
| Sunan Sinadari | Irbesartan |
| Makamantu | BMS-186295;SR-47436;Aprovel;Avapro;2-Butyl-3-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4] ba-1-en- 4-daya;2-Butyl-3-[[4-[2- (2H-tetrazol-5-yl) phenyl] phenyl] methyl] -1,3-diazaspiro [4.4] ba-1-en-4-daya |
| Lambar CAS | 138402-11-6 |
| Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
| Tsarin kwayoyin halitta | Saukewa: C25H28N6O |
| Nauyin Kwayoyin Halitta | 428.54 |
| Yawan yawa | 1.30± 0.10 g/cm3 |
| Solubility a cikin Ruwa | Mara narkewa a cikin Ruwa |
| Alamar | Ruifu Chemical |
| Abu | Ƙayyadaddun bayanai |
| Halaye | Fari zuwa Kashe-White Crystalline Foda, Dan narkewa a cikin barasa kuma a cikin methylene chloride, a zahiri maras narkewa a cikin ruwa |
| Shayewar Infrared Identification | Bakan IR yana daidai da bakan da aka samu tare da Irbesartan RS |
| Identity 2 | Lokacin riƙewa na babban kololuwa a cikin chromatogram na gwajin ya yi daidai da Irbesartan RS |
| Tsarkake / Hanyar Bincike | > 99.5% (HPLC) |
| Ruwa | <0.50% |
| Karfe masu nauyi | <0.002% |
| Ragowa akan Ignition | <0.10% |
| Abubuwa masu alaƙa | (Na HPLC) |
| USP Impurity A | <0.20% |
| Duk wani rashin tsarki da ba a gane ba | <0.10% |
| Jimlar ƙazanta | <0.50% |
| Halittar Halittar Halitta | Ya dace da bukatun USP |
| Sauran Azide | <10ppm |
| Ragowar Magani | (Na GC) |
| Ethanol | <5000ppm |
| Toluene | <890ppm |
| Dichloromethane | <3000ppm |
| N, N-Dimethylformamide | <880ppm |
| T-Butyl Methyl Ether | <5000ppm |
| Assay | 98.0 ~ 102.0% (ƙididdige shi akan tushen anhydrous) |
| Matsayin Gwaji | Matsayin Kasuwanci;USP Standard |
| Amfani | API;Antihypertensive;Domin maganin hawan jini |
Kunshin: Bottle, Aluminum tsare jakar, 25kg / kwali Drum, ko bisa ga abokin ciniki ta bukata
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi
Irbesartan (CAS: C) antagonist mai karɓar mai karɓar angiotensin II ne wanda aka yi amfani da shi musamman don maganin hauhawar jini.Sanofi Research ne ya haɓaka Irbesartan (yanzu ɓangaren Sanofi-Aventis).Sanofi-Aventis da Bristol-Myers Squibb ne ke tallata shi tare a ƙarƙashin sunayen kasuwancin Aprovel, Karvea, da Avapro.Ana amfani da Irbesartan don magance hawan jini.An ƙaddamar da Avapro a Jamus, Burtaniya da Amurka don hauhawar jini.Kamar yadda yake tare da duk angiotensin II antagonists, an nuna irbesartan don maganin hauhawar jini.Irbesartan na iya jinkirta ci gaban nephropathy na ciwon sukari kuma ana nuna shi don rage ci gaban cututtukan koda a cikin marasa lafiya da ke da nau'in ciwon sukari na 2, hauhawar jini da microalbuminuria (> 30 mg / 24 hours) ko proteinuria.Irbesartan kuma na iya rage gyare-gyaren lantarki na myocardium, ta haka ne rage yawan mace-mace na marasa lafiya da hauhawar jini, shine magani mafi inganci don maganin hauhawar jini da cututtukan zuciya.
