Ivabradine Hydrochloride CAS 148849-67-6 Tsarkake>99.5% (HPLC) Kamfanin API
Ruifu Chemical Supply Ivabradine Hydrochloride Matsakaici Tare da Babban Tsafta
Ivabradine Hydrochloride CAS 148849-67-6
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Sunan Sinadari | Ivabradine Hydrochloride |
Makamantu | Ivabradine HCl |
Lambar CAS | 148849-67-6 |
Lambar CAT | Saukewa: RF-PI1812 |
Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
Tsarin kwayoyin halitta | C27H36N2O5·HCl |
Nauyin Kwayoyin Halitta | 505.05 |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Fari zuwa Kashe-White Crystalline Foda |
Ganewa | HPLC/UV Yana Bi |
Tsarkake / Hanyar Bincike | >99.5% |
Asara akan bushewa | <1.00% (Busar da shi a 105 ℃ a cikin na'urar busar da iska ta lantarki har sai nauyi mai tsayi) |
Abubuwan Danshi | <1.00% |
Ragowa akan Ignition | <0.20% |
Max Single Najasa | <0.50% |
Jimlar ƙazanta | <0.50% |
Isomer na gani | <0.50% |
Assay | >99.5% |
Karfe masu nauyi | <20ppm |
Takamaiman Juyawa | +6.5° ~ +8.5° (akan busasshiyar tushe, 1% bayani a cikin DMSO) |
Matsayin Gwaji | Matsayin Kasuwanci |
Amfani | API |
Kunshin: Bottle, Aluminum tsare jakar, 25kg / kwali Drum, ko bisa ga abokin ciniki ta bukata
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi
Ivabradine Hydrochloride (CAS: 148849-67-6),A cikin ƙoƙari na haɓaka ma'aikatan angina ba tare da mummunan tasirin inotropic da hypotensive maras so ba da ke hade da b-adrenergic blockers da masu hana tashar tashar calcium, an bincika sabon nau'i na rage yawan ƙwayar zuciya wanda ke aiki musamman a kan kumburin sinoatrial (SA).Waɗannan ma'aikatan bradycardic suna hulɗa kai tsaye tare da tantanin halitta na bugun jini na kumburin SA da hyperpolarization- kunnawa Idan farkon bugun bugun jini na yanzu.Ivabradine ya samo asali ne a matsayin takamaiman mai hanawa na Idan halin yanzu ta hanyar hulɗa da f-tashoshi a gefen intracellular na membrane plasma.Sakamakon haka, Ivabradine yana rage saurin diastolic depolarization kuma yana rage yawan bugun zuciya.An yarda da shi don kula da angina na yau da kullun kuma yana ba da zaɓi mai dacewa ga marasa lafiya tare da contraindication ko rashin haƙuri na b-blockers.Ana kuma ci gaba da kimantawa don yuwuwar maganin cututtukan zuciya na ischemic.