L-Cysteine ​​Hydrochloride Monohydrate CAS 7048-04-6 Assay 98.5 ~ 101.0% (Titration on Dried Bassis) Factory

L-Cysteine ​​Hydrochloride Monohydrate (CAS: 7048-04-6) Hanyar Gwajin AJI97
Ganewa: Kwatanta nau'in infrared na samfurin tare da ma'auni ta hanyar fayafai bromide.
Takamaiman Juyawa [α] D20: Samfurin Busasshen, C=8, 1mol/L HCl
Halin Magani (Maɗaukaki): 1.0g a cikin 10ml na H2O, spectrophotometer, 430nm, 10mm kauri.
Chloride (Cl): 350mg, B-2
Ammonium (NH4): A-1
Sulfate (SO4): 1.2g, (1), ref: 0.50ml na 0.005mol/L H2SO4
Iron (Fe): 1.5g, Ref: 1.5ml na Iron Std.(0.01mg/ml)
Karfe masu nauyi (Pb): 2.0g, (1), pH=7, ref: 2.0ml na Pb Std.(0.01mg/ml)
Arsenic (As2O3): 2.0g, (1), ref: 2.0ml na As2O3 Std.
Sauran Amino Acids: Gwajin Samfurin: 50μg, B-6-a, sarrafawa;L-Cys·HCl·H2O 0.25μg
Asara akan bushewa: A cikin sarari, P2O5, a zafin jiki na awanni 20.
Residue on Ignition (Sulfated): AJI Test 13
Gwajin: samfurin busassun, 250mg, 0.05mol/L I2 1ml=15.762mg C3H7NO2S·HCl
Gwajin pH: 1.0g a cikin 100ml na H2O

L-Cysteine ​​Hydrochloride Monohydrate (CAS: 7048-04-6) Hanyar Gwajin USP35
BAYANI
Cysteine ​​​​Hydrochloride shine L-Cysteine ​​Hydrochloride Monohydrate kuma ya ƙunshi NLT 98.5% da NMT 101.5% na L-Cysteine ​​Hydrochloride (C3H7NO2S·HCl), ƙididdiga akan busasshen tushe.
GANO
A. RASHIN NUTSUWA <197K>
ASSAY
TSARI
Misali: 250 MG na Cysteine ​​​​Hydrochloride
Blank: Ci gaba kamar yadda aka umarce shi a cikin Bincike ba tare da Samfura ba.
Titrimetric tsarin
(Duba Titrimetry <541>)
Yanayin: Ragowar titration
Titrant: 0.1 N aidin VS
Baya titrant: 0.1 N sodium thiosulfate VS
Gano ƙarshen ƙarshen: Na gani
Analysis: Canja wurin Samfurin zuwa flask na aidin.Ƙara 20.0 ml na ruwa da 4 g na potassium iodide, da kuma Mix.Sanya maganin a cikin wanka na kankara, kuma ƙara 5 ml na 3 N hydrochloric acid da 25.0 ml na 0.1 N iodine VS.Saka abin tsayawa, kuma ba da izinin tsayawa a cikin duhu na minti 20.Titrate da wuce haddi iodine tare da Back titrant.Ƙara 3 ml na tauraro ch TS yayin da aka gabato ƙarshen ƙarshen.Ta hanyar samar da ƙaddarar Blank.Yi lissafin adadin cysteine ​​hydrochloride (C3H7NO2S·HCl) a cikin Samfurin da aka ɗauka:
Sakamako = {[(VB - VS) × N × F]/W} × 100
VB = Ƙarfin titrant baya cinye ta Blank (mL)
VS = Ƙarfin titrant baya cinye ta Samfurin (mL)
N = ainihin al'ada na baya titrant (mEq/ml)
F= ma'aunin daidai, 157.6 mg/mEq
W= Nauyin Nauyin (mg)
Sharuɗɗan karɓa: 98.5% ~ 101.5% akan busasshiyar tushe
RASHIN ZUCIYA
SAURAN WUTA <281>: NMT 0.4%
chloride da sulfate, sulfate <221>
Daidaitaccen bayani: 0.10 ml na 0.020 N sulfuric acid
Misali: 0.33 g na Cysteine ​​​​Hydrochloride
Sharuɗɗan karɓa: NMT 0.03%
IRON <241>: NMT 30ppm
KARFE MAI KYAU, Hanyar I <231>: NMT 15ppm
Abubuwan da suka danganci
Maganin N-Ethylmaleimide: 40 mg/mL na N-ethylmaleimide a cikin barasa
Daidaitaccen Maganin haja: Narkar da 20 MG na USP L-Cysteine ​​Hydrochloride RS a cikin 10.0 ml na ruwa.Ƙara 10.0 ml na maganin N-Ethylmaleimide, da haɗuwa.Bada maganin ya tsaya na minti 5 kafin amfani.
Daidaitaccen bayani: 0.05 mg/mL daga Standard stock bayani a cikin ruwa.[ NOTE-Wannan bayani yana da maida hankali daidai da 0.5% na maganin Samfurin.]
Maganin dacewa da tsarin: Canja wurin 10 MG na USP L-Tyrosine RS da 10 ml na Ma'auni na Ma'auni zuwa 25-mL flask volumetric.Tsarma da ruwa zuwa girma.
Maganin samfurin samfurin: Canja wurin 0.2 g na Cysteine ​​​​Hysteine ​​​​Hysteine ​​​​Hysteine ​​​​Hysteine ​​​​Hysteine ​​​​Hysteine ​​​​Hydrochloride zuwa 10-mL flask volumetric, narke, da tsarma da ruwa zuwa girma.
Maganin samfurin: Zuwa 5.0 ml na Maganin Haɗin Samfurin ƙara 5.0 ml na maganin N-Ethylmaleimide, da haɗuwa.Bada maganin ya tsaya na minti 5 kafin amfani.
Tsarin Chromatographic (Duba Chromatography <621>, Chromatography na bakin-Layer.)
Yanayin: TLC
Adsorbent: 0.25-mm Layer na chromatographic silica gel cakuda
Girman aikace-aikacen: 5μL
Haɓaka tsarin ƙarfi: Butyl barasa, glacial acetic acid, da ruwa (3:1:1)
Fesa reagent: 2 mg/mL na ninhydrin a cikin cakuda butyl barasa da 2N acetic acid (95:5)
Dacewar tsarin
Bukatun dacewa: chromatogram na tsarin dacewa da tsarin yana nuna aibobi biyu a sarari.
Bincike
Samfura: Daidaitaccen bayani, Maganin dacewa da tsarin, da Samfurin bayani.
Bayan shan iska farantin, fesa da Fesa reagent, kuma zafi tsakanin 100 ° da 105 ° na 15 min.Yi nazarin farantin a ƙarƙashin farin haske.
Sharuɗɗan karɓa: Duk wani wuri na biyu na samfurin samfurin bai fi girma ko mafi tsanani fiye da ainihin tabo na daidaitaccen bayani ba.
Najasa ɗaya: NMT 0.5%
Jimlar ƙazanta: NMT 2.0%
MAKAMMAN JARRABAWA
Juyawa ta gani, Jujjuya ta musamman <781S>
Maganin samfurin: 80 mg/mL a cikin 6 N hydrochloric acid
Sharuɗɗan karɓa: +5.7° zuwa +6.8°
RASHIN RASHI <731>: Busa samfurin a zafin jiki a matsa lamba da bai wuce 5 mm na mer cury ba na awa 24: yana rasa 8.0% ~ 12.0% na nauyinsa.
KARIN BUKATA
KYAUTA DA AJIYA: Ajiye a cikin kwantena da aka rufe sosai.
MATSAYIN NAZARI NA USP <11>
USP L-Cysteine ​​​​Hydrochloride RS
USP L-Tyrosine RS