L-Proline CAS 147-85-3 (H-Pro-OH) Assay 98.5 ~ 101.0% Babban Ingancin Factory
Shanghai Ruifu Chemical Co., Ltd. shine babban masana'anta da mai ba da kayayyaki na L-Proline (H-Pro-OH; Abbreviated Pro ko P) (CAS: 147-85-3) tare da babban inganci, ƙarfin samarwa 2000 Ton a kowace shekara.A matsayin daya daga cikin manyan masu samar da amino acid a kasar Sin, Ruifu Chemical yana samar da amino acid har zuwa matsayin kasa da kasa, kamar AJI, USP, EP, JP da FCC.Za mu iya samar da COA, isarwa a duniya, ƙanana da yawa da ake samu.Idan kuna sha'awar L-Proline,Please contact: alvin@ruifuchem.com
Sunan Sinadari | L-Proline |
Makamantu | H-Pro-OH;L (-) - Proline;L-Pro;Taƙaitaccen Pro ko P;Laevo-Proline;Proline;(-)-Proline;(S)-(-) Proline;(S)-Proline;(S) -Pyrrolidine-2-Carboxylic Acid;(S) -2-Pyrrolidinecarboxylic Acid;(-)-2-Pyrrolidinecarboxylic acid;L-Pyrrolidine-2-carboxylic acid;L-a-Pyrrolidinecarboxylic acid;(S)-2-Carboxypyrrolidine |
Matsayin Hannun jari | A hannun jari, Ƙarfin Samar da Ton 2000 a kowace shekara |
Lambar CAS | 147-85-3 |
Tsarin kwayoyin halitta | Saukewa: C5H9NO2 |
Nauyin Kwayoyin Halitta | 115.13 |
Matsayin narkewa | 228 ℃ (Dec.) (lit.) |
Yawan yawa | 1.35 |
M | Hygroscopic |
Ruwan Solubility | Mai narkewa a cikin Ruwa, H2O: 50 mg/mL, Kusan Bayyanawa |
Solubility | Mai Soluble Kyauta a cikin Glacial Acetic Acid, Mai Rarraba Mai Soluble a cikin Ethanol.Haƙiƙa maras narkewa a cikin Ether |
Adana Yanayin. | An rufe shi a bushe, Ajiye a Zazzabin ɗaki |
COA & MSDS | Akwai |
Rabewa | Amino Acids |
Alamar | Ruifu Chemical |
Lambobin haɗari | Xi, Xn |
Bayanin Hatsari | R36/37/38 - Haushi da idanu, tsarin numfashi da fata. R22 - Yana cutarwa idan an haɗiye shi |
Bayanan Tsaro | S24/25 - Guji hulɗa da fata da idanu. S36/37/39 - Sanya tufafin kariya masu dacewa, safar hannu da kariya ta ido/ fuska. S26 - Idan ana hulɗa da idanu, kurkura nan da nan da ruwa mai yawa kuma ku nemi shawarar likita. |
WGK Jamus | 3 |
RTECS | Saukewa: TW3584000 |
F | 3-10 |
Farashin TSCA | Ee |
HS Code | 293399009 |
Abubuwa | Ka'idojin dubawa | Sakamako |
Bayyanar | Farin lu'ulu'u ko lu'ulu'u ko foda;Dandanni Mai Dadi | Ya dace |
Ganewa | Infrared Absorption Spectrum | Ya dace |
Takamaiman Juyawa [α] 20/D | -84.5° zuwa -86.0° (Sample Busasshen, C=4, H2O) | -85.51° |
Yanayin Magani (Transmittance) | Bayyananne kuma mara launi ≥98.0% | 98.5% |
Chloride (Cl) | ≤0.020% | <0.020% |
Sulfate (SO4) | ≤0.020% | <0.020% |
Ammonium (NH4) | ≤0.020% | <0.020% |
Iron (F) | ≤10ppm | <10ppm |
Karfe masu nauyi (Pb) | ≤10ppm | <10ppm |
Arsenic (As2O3) | ≤1.0pm | <1.0pm |
Sauran Amino Acids | Ba a Gane Chromatographically | Ya dace |
Asara akan bushewa | ≤0.30% (a 105 ℃ na 3 hours) | 0.16% |
Ragowa akan ƙonewa (Sulfated) | ≤0.10% | 0.07% |
Assay | 98.5 zuwa 101.0% (Titration, as Dry Bassis) | 99.7% |
Gwajin pH | 5.9 zuwa 6.9 (1.0g a cikin 10ml na H2O) | 6.2 |
Ninhydrin-Kyakkyawan Abubuwa | Ya dace | Ya dace |
Asalin | Daga Ba Na Dabba | Ya dace |
Ragowar Magani | Ya dace | Ya dace |
Kammalawa | Haɗu da AJI97;EP;USP;Ƙididdigar Gwajin JP | |
Babban Amfani | Amino acid;Abubuwan Abincin Abinci;Magunguna;Ƙarin Gina Jiki |
L-Proline (H-Pro-OH) (CAS: 147-85-3) AJI 97 Hanyar Gwaji
Ganewa: Kwatanta nau'in infrared na samfurin tare da ma'auni ta hanyar fayafai bromide.
Takamaiman Juyawa [α] 20/D: Samfurin Busasshen, C=4, H2O
Halin Magani (Maɗaukaki): 1.0g a cikin 10ml na H2O, spectrophotometer, 430nm, 10mm kauri.
Chloride (Cl): 0.7g, A-1, ref: 0.40ml na 0.01mol/L HCl
Ammonium (NH4): B-1
Sulfate (SO4): 1.2g, (1), ref: 0.50ml na 0.005mol/L H2SO4
Iron (Fe): 1.5g, Ref: 1.5ml na Iron Std.(0.01mg/ml)
Karfe masu nauyi (Pb): 2.0g, (1), Ref: 2.0ml na Pb Std.(0.01mg/ml)
Arsenic (As2O3): 2.0g, (1), ref: 2.0ml na As2O3 Std.
Sauran Amino Acids: Samfurin Gwaji: 30μg, B-6-a
Asarar bushewa: a 105 ℃ na 3 hours.
Assay: samfurin bushe, 120mg, (1), 3ml na formic acid, 50ml na glacial acetic acid, 0.1mol/L HCLO4 1ml=11.513mg C5H9NO2
Gwajin pH: 1.0g a cikin 10ml na H2O
L-Proline (H-Pro-OH) (CAS: 147-85-3) Hanyar Gwajin USP35
BAYANI
Proline ya ƙunshi NLT 98.5% da NMT 101.5% na L-Proline (C5H9NO2), ƙididdiga akan busasshen tushe.
GANO
A. RASHIN NUTSUWA <197K>
ASSAY
TSARI
Misali: 110 MG na Proline
Blank: Mix 3 ml na formic acid da 50 ml na glacial acetic acid.
Titrimetric tsarin
(Duba Titrimetry <541>)
Yanayin: Kai tsaye titration
Titrant: 0.1 N perchloric acid VS
Gano ƙarshen ƙarshen: Potentiometric
Analysis: Narkar da Samfurin a cikin 3 ml na formic acid da 50ml na glacial acetic acid.Titrate tare da Titrant.Yi ƙudurin Blank.
Yi lissafin adadin Proline (C5H9NO2) a cikin Samfurin da aka ɗauka:
Sakamako = {[(VS-VB) x N x F]/W} x100
VS = ƙarar Titrant da Samfurin (mL) ya cinye
VB = ƙarar Titrant da Blank (mL) ke cinyewa
N = ainihin al'ada na Titrant (mEq/ml)
F= ma'aunin daidai, 115.1 mg/mEq
W= Nauyin Nauyin (mg)
Sharuɗɗan karɓa: 98.5% ~ 101.5% akan busasshiyar tushe
RASHIN ZUCIYA
SAURAN WUTA <281>: NMT 0.4%
chloride da sulfate, Chloride <221>
Daidaitaccen bayani: 0.50mL na 0.020 N hydrochloric acid
Misali: 0.73g na Proline
Sharuɗɗan karɓa: NMT 0.05%
chloride da sulfate, sulfate <221>
Daidaitaccen bayani: 0.10ml na 0.020 N sulfuric acid
Misali: 0.33g na Proline
Sharuɗɗan karɓa: NMT 0.03%
IRON <241>: NMT 30ppm
KARFE MAI KYAU, Hanyar I <231>: NMT 15ppm
Abubuwan da suka danganci
Maganin dacewa da tsarin: 0.4mg/mL kowane na USP L-Proline RS da USP L-Threonine RS a cikin 0.1 N hydrochloric acid
Daidaitaccen bayani: 0.05mg/mL na USP L-Proline RS a cikin 0.1 N hydrochloric acid.[NOTE-Wannan bayani yana da maida hankali daidai da 0.5% na na samfurin bayani.]
Maganin samfurin: 10mg/mL na Proline a cikin 0.1 N hydrochloric acid
Tsarin chromatographic
(Duba Chromatography <621>, Chromatography na bakin-Layer.)
Yanayin: TLC
Adsorbent: 0.25-mm Layer na chromatographic silica gel cakuda
Girman aikace-aikacen: 5μL
Haɓaka tsarin ƙarfi: Butyl barasa, glacial acetic acid, da ruwa (3:1:1)
Fesa reagent: 2 mg/mL na ninhydrin a cikin cakuda butyl barasa da 2N acetic acid (95:5)
Dacewar tsarin
Bukatun dacewa: chromatogram na tsarin dacewa da tsarin yana nuna aibobi biyu a sarari.
Bincike
Samfura: Maganin dacewa da tsarin, daidaitaccen bayani, da Samfurin bayani.
Bayan shan iska farantin, fesa da Fesa reagent, kuma zafi tsakanin 100 ° da 105 ° na 15 min.Yi nazarin farantin a ƙarƙashin farin haske.
Sharuɗɗan karɓa: Duk wani wuri na biyu na samfurin samfurin bai fi girma ko mafi tsanani fiye da ainihin tabo na daidaitaccen bayani ba.
Najasa ɗaya: NMT 0.5%
Jimlar ƙazanta: NMT 2.0%
MAKAMMAN JARRABAWA
Juyawa ta gani, Jujjuya ta musamman <781S>
Maganin samfurin: 40 mg / ml a cikin ruwa
Sharuɗɗan karɓa: -84.3° zuwa -86.3°
RASHIN RASHI <731>: bushe samfurin a 105 ℃ na 3 h: yana rasa NMT 0.4% na nauyinsa.
KARIN BUKATA
KYAUTA DA AJIYA: Ajiye a cikin kwantena da aka rufe sosai.
MATSAYIN NAZARI NA USP <11>
USP L-Proline RS
USP L-Threonine RS
Kunshin: Fluorinated Bottle, 25kg/bag, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Hygroscopic.Ajiye a cikin kwantena da aka rufe a wuri mai sanyi, bushe da iska mai nisa daga abubuwan da ba su dace ba.Kare daga haske da danshi.Wanda bai dace ba tare da magunguna masu ƙarfi masu ƙarfi.
Yadda ake siya?Da fatan za a tuntuɓiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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Fa'idodi?Babban inganci, farashi mai araha, sabis na ƙwararru da tallafin fasaha, bayarwa da sauri.
inganciTabbaci?Tsananin kula da ingancin inganci.Kayan aikin ƙwararru don bincike sun haɗa da NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, gwajin ƙayyadaddun ƙwayoyin cuta, da sauransu.
Misali?Yawancin samfurori suna ba da samfurori kyauta don ƙima mai kyau, farashin jigilar kaya ya kamata a biya ta abokan ciniki.
Binciken Masana'antu?Ma'aikata duba maraba.Da fatan za a yi alƙawari a gaba.
MOQ?Babu MOQ.Karamin tsari abin karɓa ne.
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L-Proline (H-Pro-OH; Abbreviated Pro ko P) (CAS: 147-85-3) amino acid ne tsaka tsaki.Ko da yake proline an rarraba shi azaman amino acid, yana magana sosai da imino acid, tunda yana ɗauke da rukunin imino (carbon-nitrogen double bond).Saboda sarkar gefen sa na pyrrolidine cyclic an rarraba shi azaman amino acid aliphatic nonpolar.
Aikace-aikace
Ana amfani dashi a cikin bincike na biochemical, magani don rashin abinci mai gina jiki, rashi sunadaran gina jiki, cututtuka na ciki, ƙonewa da ƙarin furotin bayan aiki.
1. A matsayin amino acid, yana iya ƙara abubuwan gina jiki kuma shine ɗanyen abu don jiko na amino acid.
2. Yana da tasiri ga hauhawar jini kuma yana da mahimmancin tsaka-tsaki don haɗuwa da magungunan antihypertensive na farko kamar captopril da enalapril.
3. A matsayin kari na abinci mai gina jiki, zai iya inganta juriya na kyallen takarda da ƙara yawan rayuwa na callus.Abubuwan dandano tare da zazzaɓin sukari suna faruwa halayen amino-carbonyl, na iya haifar da abubuwan dandano na musamman.China GB 2760-86 tana bayarwa ana iya amfani dashi azaman yaji.
4. Yana iya saukaka lalacewar danniya na gishiri yadda ya kamata ga tsarin mitochondrial na tsire-tsire da aka sabunta shinkafa.
5. L-Proline shine amino acid maras muhimmanci.Peptides sun haɗa zuwa proline, yana mai da shi tubalin ginin mai amfani ga sunadaran.Ana iya amfani da shi azaman ɓangaren watsa labarai na al'adar tantanin halitta don kasuwancin biomanufacturing sunadaran ƙwayoyin cuta da ƙwayoyin rigakafi na monoclonal.
6. Ana amfani da L-Proline azaman masu haɓakawa na asymmetric a cikin haɓakar ƙwayoyin cuta da cyclization na aldol asymmetric.Yana da wani sashi mai aiki na collagen kuma yana shiga cikin aikin da ya dace na haɗin gwiwa da tendons.Yana samun amfani a cikin magunguna, aikace-aikacen fasahar kere-kere saboda kayan sa na osmoprotectant.
Aiki:
1. L-Proline da abubuwan da suka samo asali ana amfani dasu azaman asymmetric catalysts a cikin halayen kwayoyin halitta.Ragewar CBS da ƙayyadaddun ƙayyadaddun ƙayyadaddun aldol fitattun misalai ne.
2. L-Proline ne osmoprotectant sabili da haka ana amfani dashi a cikin magunguna da yawa, aikace-aikacen fasahar kere kere. A cikin shayarwa, sunadaran masu arziki a cikin proline suna haɗuwa tare da polyphenols don samar da hazo.
3. L-Proline na ɗaya daga cikin muhimman amino acid don haɗa furotin ɗan adam.Ana amfani dashi ko'ina a cikin masana'antar abinci da likitanci, kuma muhimmin matsakaici ne don haɗa masu hana ACE kamar Captopril da Enalapril.Hakanan yana ɗaya daga cikin mahimman albarkatun ɗanyen amino acid transfusion.
4. An yi amfani da L-Proline a duk duniya azaman ƙari na abinci, mai kara kuzari da albarkatun ƙasa na masana'antar sinadarai mai kyau.