Lasofoxifene Tartrate CAS 190791-29-8 Chiral Tsafta ≥99.0% Tsafta ≥98.0% (HPLC) API Babban Tsabta
Samar da Mai ƙira tare da Tsaftataccen Tsafta da Tsayayyen inganci
Sunan Chemical: Lasofoxifene Tartrate
Saukewa: 190791-29
Lasofoxifene Tartrate (CAS: 190791-29-8) a cikin maganin Osteoporosis na Postmenopausal
Sunan Sinadari | Lasofoxifene Tartrate |
Makamantu | (5R,6S) -5,6,7,8-Tetrahydro-6-phenyl-5-[4-[2- (1-pyrrolidinyl) ethoxy] phenyl] -2-naphthalenol Tartrate Oporia |
Lambar CAS | 190791-29-8 |
Lambar CAT | RF-API20 |
Matsayin Hannun jari | A Hannun jari, Ma'aunin Samfuran Har zuwa Daruruwan Kilogram |
Tsarin kwayoyin halitta | Saukewa: C28H31NO2.ClH |
Nauyin Kwayoyin Halitta | 450.019 |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Fari zuwa Kashe-Farin Foda |
Danshi (KF) | ≤0.50% |
Karfe masu nauyi | ≤20ppm |
Chiral Tsafta | ≥99.0% |
Tsarkake / Hanyar Bincike | ≥98.0% (HPLC) |
Asara akan bushewa | ≤0.50% |
Ragowa akan Ignition | ≤0.50% |
Matsayin Gwaji | Pharmacopoeia na kasar Sin (CP);Matsayin Kasuwanci |
Amfani | Sinadarin Magunguna Mai Aiki (API);Osteoporosis na postmenopausal |
Kunshin: Bottle, Aluminum tsare jakar, Kwali drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.
Shanghai Ruifu Chemical Co., Ltd. shine babban masana'anta kuma mai samar da Lasofoxifene Tartrate (CAS: 190791-29-8) tare da babban inganci.
Lasofoxifene Tartrate shine ƙarni na uku, mai zaɓin mai karɓar isrogen mai karɓa (SERM) mara amfani.Yana zaɓin ɗaure ga ɗan adam ERalpha tare da ƙimar IC50 na 1.5 nM kuma yana hana asarar kashi a cikin berayen ovariectomized.A cikin nazarin asibiti na postmenopausal osteoporosis, 0.5 mg / day lasofoxifene an hade shi da rage hadarin da ba a yi ba da kuma vertebral fractures, ER-positive ciwon nono, cututtuka na zuciya da jijiyoyin jini, da bugun jini amma ya kara hadarin venous thromboembolic abubuwan da suka faru.Hakanan an nuna Lasofoxifene don yin aiki azaman agonist mai juzu'i a mai karɓar CB2 cannabinoid, yana nuna yiwuwar sake dawo da shi azaman magani don alamun da CB2 ke da manufa.