LCZ696 Matsakaici CAS 1426129-50-1 Tsabtace ≥98.0% (HPLC) na ≥99.0% Babban Tsabta
Bayar da Kasuwanci LCZ696 (CAS: 936623-90-4) Matsakaici masu alaƙa:
(R) -tert-Butyl (1- ([1,1-biphenyl] -4-yl) -3-hydroxypropan-2-yl) carbamate CAS: 1426129-50-1
(R, E) -5- (1,1'-biphenyl-4-yl) -4-((tert-butoxycarbonyl)amino) -2-methylpent-2-enoic acid CAS: 1012341-48-8
(2R,4S) -5- (1,1'-biphenyl-4-yl) -4-((tert-butoxycarbonyl) amino) -2-methylpentanoic acid CAS: 1012341-50-2
(2R,4S) -ethyl 5- (1,1'-biphenyl-4-yl) -4-amino-2-methylpentanoate HCl CAS: 149690-12-0
AHU-377 (hemicalcium gishiri) CAS: 1369773-39-6
AHU-377;Sacubitril CAS: 149709-62-6
LCZ696;Entresto;Cakuda Sacubitril tare da Valsartan CAS: 936623-90-4
| Sunan Sinadari | (R) -tert-Butyl (1- ([1,1-biphenyl] -4-yl) -3-hydroxypropan-2-yl) carbamate |
| Makamantu | Saukewa: LCZ696 |
| Lambar CAS | 1426129-50-1 |
| Lambar CAT | Saukewa: RF-PI169 |
| Matsayin Hannun jari | A Hannun jari, Ma'aunin Samfuran Har zuwa Daruruwan Kilogram |
| Tsarin kwayoyin halitta | Saukewa: C20H25NO3 |
| Nauyin Kwayoyin Halitta | 327.42 |
| Alamar | Ruifu Chemical |
| Abu | Ƙayyadaddun bayanai |
| Bayyanar | Fari zuwa Kashe-Farin Foda |
| Tsarkake / Hanyar Bincike | ≥98.0% (HPLC) |
| Enantiomeric wuce haddi | yi: ≥99.0% |
| Danshi (KF) | ≤1.0% |
| Abubuwan da suka danganci A | ≤1.0% (RRT=0.5) A=(R) -3-([1,1'-biphenyl] -4-yl) -2-aminopropan-1-ol |
| Abubuwan da suka danganci B | ≤1.0% (RRT=0.85) B=Triphenylphosphine oxide |
| Sauran Abubuwan | ≤1.0% |
| Jimlar ƙazanta | ≤2.0% |
| Matsayin Gwaji | Matsayin Kasuwanci |
| Amfani | Matsakaicin LCZ696 (CAS: 936623-90-4) a cikin jiyya na HFrEF |
Kunshin: Bottle, Aluminum tsare jakar, Kwali drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.
Mai ƙera tare da Babban Tsafta da Ƙarfin Ƙarfi
Bayar da Kasuwanci LCZ696 (CAS: 936623-90-4) Matsakaici masu alaƙa:
(R) -tert-Butyl (1- ([1,1-biphenyl] -4-yl) -3-hydroxypropan-2-yl) carbamate CAS: 1426129-50-1
(R, E) -5- (1,1'-biphenyl-4-yl) -4-((tert-butoxycarbonyl)amino) -2-methylpent-2-enoic acid CAS: 1012341-48-8
(2R,4S) -5- (1,1'-biphenyl-4-yl) -4-((tert-butoxycarbonyl) amino) -2-methylpentanoic acid CAS: 1012341-50-2
(2R,4S) -ethyl 5- (1,1'-biphenyl-4-yl) -4-amino-2-methylpentanoate HCl CAS: 149690-12-0
AHU-377 (hemicalcium gishiri) CAS: 1369773-39-6
AHU-377;Sacubitril CAS: 149709-62-6
LCZ696;Entresto;Cakuda Sacubitril tare da Valsartan CAS: 936623-90-4
LCZ696 magani ne na gwaji wanda Novartis Pharmaceutical na Amurka ya kirkira don kula da marasa lafiya masu fama da gazawar zuciya tare da rage juzu'in fitarwa (HFrEF).Ciwon zuciya cuta ce mai hatsarin gaske.Zuciyar mai haƙuri ba za ta iya fitar da isasshen jini don samar da jiki ba, kuma ya bayyana alamun dyspnea, gajiya da riƙe ruwa a hankali, sannan a hankali ya karu, yana tasiri sosai ga ingancin rayuwa.LCZ696 na iya haɓaka kariyar dabi'a ta jiki daga gazawar zuciya, da kuma haɓaka matakin peptides na natriuretic da sauran peptides na endogenous vasoactive, da hana tsarin renin-angiotensin-aldosterone (RAAS).LCZ696 ya haɗu tare da Novartis's Magungunan Hawan Jini (Diovan, sunan jinsin: valsartan) da gwajin gwajin gwajin AHU-377.AHU377 yana toshe hanyar peptides biyu da ke da alhakin rage hawan jini.Diovan yana inganta vasodilatation kuma yana motsa jiki don fitar da sodium da ruwa.
