Lesinurad (RDEA 594) CAS 878672-00-5 Tsafta > 99.5% (HPLC) Assay 98.0 ~ 102.0%
Shanghai Ruifu Chemical Co., Ltd. shine babban kamfani na Lesinurad (RDEA 594) (CAS: 878672-00-5) tare da babban inganci.Ruifu Chemical na iya samar da isar da saƙo na duniya, farashi mai gasa, kyakkyawan sabis, ƙanana da adadi mai yawa akwai.Sayi Lesinurad da Matsakaici,Please contact: alvin@ruifuchem.com
| Sunan Sinadari | Lesinurad |
| Makamantu | 2-[5-Bromo-4- (4-Cyclopropylnaphthalen-1-yl)-4H-1,2,4-Triazol-3-yl]thio] acetic acid;2-[5-Bromo-4- (4-Cyclopropyl-1-Naphthalenyl)-4H-1,2,4-Triazol-3-yl]thio] -Acetic Acid;RDEA 594;RDEA-594;RDEA594;Zurampic |
| Matsayin Hannun jari | A Stock, Kasuwancin Kasuwanci |
| Lambar CAS | 878672-00-5 |
| Tsarin kwayoyin halitta | Saukewa: C17H14BrN3O2S |
| Nauyin Kwayoyin Halitta | 404.28 g/mol |
| Matsayin narkewa | > 171 ℃ (Dec.) |
| Yawan yawa | 1.72± 0.10 g/cm3 |
| COA & MSDS | Akwai |
| Asalin | Shanghai, China |
| Alamar | Ruifu Chemical |
| Abubuwa | Ka'idojin dubawa | Sakamako |
| Bayyanar | Fari zuwa Kashe-Farin Foda | Kashe-Farin Foda |
| Ganewa | Lokacin riƙewa na babban kololuwar samfurin maganin ya dace da ma'aunin tunani | Ya bi |
| Ruwa ta Karl Fischer | <0.50% | 0.14% |
| Ragowa akan Ignition | <0.10% | 0.03% |
| Karfe masu nauyi (Pb) | ≤10ppm | <10ppm |
| Abubuwa masu alaƙa (HPLC) | ||
| Mafi girman ƙazanta Single | <0.20% | 0.07% |
| Jimlar ƙazanta | <1.00% | 0.24% |
| Tsarkake / Hanyar Bincike | >99.5% (Yankin HPLC) | 99.76% |
| Assay | 98.0 ~ 102.0% | 99.6% |
| Infrared Spectrum | Yayi daidai da Tsarin | Ya bi |
| Farashin NMR Spectrum | Yayi daidai da Tsarin | Ya bi |
| Kammalawa | An gwada samfurin kuma ya dace da ƙayyadaddun da aka bayar | |
Kunshin:Bottle, Aluminum tsare jakar, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye akwati sosai kuma a adana a wuri mai sanyi, bushe (2 ~ 8 ℃) da ma'ajin da ke da isasshen iska daga abubuwan da ba su dace ba.Kare daga haske da danshi.
Jirgin ruwa:Isar da shi zuwa duniya ta iska, ta FedEx / DHL Express.Bayar da isarwa cikin sauri kuma abin dogaro.
Yadda ake siya?Da fatan za a tuntuɓiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Kwarewar Shekaru 15?Muna da fiye da shekaru 15 na gwaninta a cikin ƙira da fitarwa na matsakaicin matsakaicin magunguna masu inganci ko sinadarai masu kyau.
Manyan Kasuwanni?Sayarwa zuwa kasuwannin cikin gida, Arewacin Amurka, Turai, Indiya, Koriya, Jafananci, Australia, da sauransu.
Fa'idodi?Babban inganci, farashi mai araha, sabis na ƙwararru da tallafin fasaha, bayarwa da sauri.
inganciTabbaci?Tsananin kula da ingancin inganci.Kayan aikin ƙwararru don bincike sun haɗa da NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, gwajin ƙayyadaddun ƙwayoyin cuta, da sauransu.
Misali?Yawancin samfurori suna ba da samfurori kyauta don ƙima mai kyau, farashin jigilar kaya ya kamata a biya ta abokan ciniki.
Binciken Masana'antu?Ma'aikata duba maraba.Da fatan za a yi alƙawari a gaba.
MOQ?Babu MOQ.Karamin tsari abin karɓa ne.
Lokacin Bayarwa? Idan cikin hannun jari, garantin isar da kwana uku.
Sufuri?By Express (FedEx, DHL), ta Air, ta Teku.
Takardu?Bayan sabis na tallace-tallace: COA, MOA, ROS, MSDS, da dai sauransu za a iya ba da su.
Haɗin Kan Al'ada?Zai iya ba da sabis na haɗawa na al'ada don dacewa da buƙatun bincikenku.
Sharuɗɗan Biyan kuɗi?Za a fara aiko da daftari na Proforma bayan tabbatar da oda, an rufe bayanan bankin mu.Biya ta T/T (Telex Transfer), PayPal, Western Union, da dai sauransu.
Hukumar Kula da Abinci da Magunguna ta Amurka (FDA) ta amince da Lesinurad (RDEA 594) (CAS: 878672-00-5) a ranar 22 ga Disamba, 2015, sannan Hukumar Kula da Magunguna ta Turai (EMA) ta amince da ita a ranar 18 ga Fabrairu, 2016. Tun da farko Ardea ne ya samar da fili.AstraZeneca ya sami kamfanin a cikin 2012, wanda hakan ya sami samfurin.Sunan kasuwancin maganin shine Zurampic® a Amurka da Tarayyar Turai.Lesinurad shine farkon wanda aka yarda da mai hana jigilar urate reuptake (URAT1), haɗe tare da masu hana xanthine oxidase don kula da gout masu alaƙa da hyperuricemia.
Lesinurad, sunan kasuwanci Zurampic.Lesinurad a hade tare da xanthine oxidase inhibitor (XOI) don ciwon hyperuricemia gout.Tsarin aikinsa shine don taimakawa kodan fitar da uric acid, kuma yana aiki ta hanyar hana ayyukan masu jigilar kaya da ke da hannu wajen dawo da uric acid a cikin kodan.
Lesinurad ya hana aikin jigilar uric acid (IC50 = 3.36 μM) na hURAT1 (URAT1 mutum), wanda ya fi sau 20 tasirin hanawa akan rURAT1 (rat URAT1) (IC50=74.84 μM).Lesinurad yana hana hURAT1 ta hanyar hulɗar maɓalli na sauran amino acid Phe365.
