Letrozole CAS 112809-51-5 API Factory Aromatase Inhibitor II High Quality
Ƙarfafawa tare da Babban Tsafta da Ƙarfin Ƙarfi
Sunan Chemical: Letrozole
Saukewa: 112809-51
Mai hana Aromatase II
API High Quality, Kasuwancin Kasuwanci
| Sunan Sinadari | Letrozole |
| Makamantu | CGS-20267;Femara |
| Lambar CAS | 112809-51-5 |
| Lambar CAT | RF-API86 |
| Matsayin Hannun jari | A Hannun jari, Ma'aunin Samfuran Har zuwa Daruruwan Kilogram |
| Tsarin kwayoyin halitta | Saukewa: C17H11N5 |
| Nauyin Kwayoyin Halitta | 285.3 |
| Matsayin narkewa | 181.0 zuwa 183.0 ℃ |
| Alamar | Ruifu Chemical |
| Abu | Ƙayyadaddun bayanai |
| Bayyanar | Fari zuwa Kashe-White Crystalline Foda |
| Solubility | Mai Soluble Kyauta a Dichloromethane, Dan Soluble a cikin Ethanol kuma Mai Sauƙi A Cikin Ruwa. |
| Gano IR | Bakan samfurin yayi daidai da na ma'aunin tunani |
| Bayanin HPLC | Lokacin riƙewar samfurin gwajin yayi daidai da na ƙa'idar tunani |
| Abubuwan Ruwa (na KF) | ≤0.30% |
| Ragowa akan Ignition | ≤0.10% |
| Abubuwa masu alaƙa | |
| Abubuwan da suka danganci A | ≤0.30% |
| Abubuwan da suka danganci B | ≤0.20% |
| Duk Wani Tsaftar Da Ba A Fayyace Ba | ≤0.10% |
| Jimlar ƙazantattun da ba a fayyace su ba | ≤0.30% |
| Jimlar ƙazanta | ≤0.50% |
| Ragowar Magani | |
| Ethyl acetate | ≤0.50% |
| Methanol | ≤0.30% |
| Ethanol | ≤0.50% |
| DMF | ≤0.088% |
| Karfe masu nauyi | ≤10ppm |
| Assay | 98.0% ~ 102.0% (a kan anhydrous-akai) |
| Rayuwar Rayuwa | Watanni 24 |
| Matsayin Gwaji | Matsayin Kasuwanci |
| Amfani | API, Mai hana Aromatase II |
Kunshin: Bottle, Aluminum tsare jakar, Kwali drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.
Letrozole (CAS 112809-51-5) wani ɓangare ne na sabon ƙarni na masu hana aromatase mai zaɓaɓɓen zaɓi kuma shine ƙirar benzotriazole ta wucin gadi.Letrozole yana hana aromatase don rage matakan estrogen, don haka yana hana estrogen daga haɓakar haɓakar ƙwayar cuta.Ayyukansa a cikin vivo yana da ƙarfi sau 150-250 fiye da na ƙarni na farko na aromatase inhibitor Amarante.Kamar yadda yake da zaɓi sosai, ba zai tasiri glucocorticoid ba, mineralocorticoid da ayyukan thyroid;ko da a high dosages, shi ba zai da wani inhibiting effects a kan adrenal corticosteroid mugunya, ba shi babban magani index.Letrozole ba shi da guba mai lalacewa ga kowane tsarin jiki da gabobin da aka yi niyya, ba shi da mutagenicity da tasirin carcinogenic, yana da ƙarancin sakamako masu illa mai guba, yana da jurewa sosai, kuma yana da tasirin anticancer fiye da sauran masu hana aromatase da magungunan antiestrogen.Letrozole ya dace da ci-gaba da ciwon nono postmenopausal marasa lafiya da ba su amsa ga estrogen-suppressing jiyya da kuma farkon ciwon nono magani.Ana amfani da shi don kula da marasa lafiya na postmenopausal tare da ci gaba da ciwon nono kuma yana aiki azaman jiyya na layi na biyu don bin maganin antiestrogen da bai yi nasara ba.
