Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8 Tsarkake>98.0% (GC) Lenvatinib Mesylate Intermediate Factory
Ruifu Chemical Supply Lenvatinib Mesylate Matsakaici Tare da Babban Tsafta
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1- (2-Chloro-4-Hydroxyphenyl) -3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dion CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4
Sunan Sinadari | Methyl 4-Amino-2-Methoxybenzoate |
Makamantu | 4-Amino-2-Methoxybenzoic Acid Methyl Ester;Methyl 4-Amino-o-Anisate;4-Amino-o-Anisic Acid Methyl Ester |
Lambar CAS | 27492-84-8 |
Lambar CAT | RF-PI1974 |
Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
Tsarin kwayoyin halitta | Saukewa: C9H11NO3 |
Nauyin Kwayoyin Halitta | 181.19 |
Yawan yawa | 1.179± 0.060 g/cm3 |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Fari zuwa Kashe-Farin Foda ko Lu'ulu'u |
Tsarkake / Hanyar Bincike | > 98.0% (GC) |
Tsarkake / Hanyar Bincike | 97.5 ~ 102.5 (Titration mara kyau) |
Matsayin narkewa | 157.0 ~ 161.0 ℃ |
Asara akan bushewa | <1.00% |
Jimlar ƙazanta | <2.0% |
Infrared Spectrum | Yayi daidai da Tsarin |
Abubuwan da aka bayar na Proton NMR Spectrum | Yayi daidai da Tsarin |
Matsayin Gwaji | Matsayin Kasuwanci |
Amfani | Matsakaicin Lenvatinib Mesylate (CAS: 857890-39-2) |
Kunshin: Bottle, Aluminum tsare jakar, 25kg / kwali Drum, ko bisa ga abokin ciniki ta bukata
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi
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Methyl 4-Amino-2-Methoxybenzoate (CAS: 27492-84-8) za a iya amfani dashi azaman matsakaici na Lenvatinib Mesylate (CAS: 857890-39-2).Lenvatinib magani ne na ciwon daji na thyroid wanda Eisai Corporation na Japan ya haɓaka (Lambar: E7080), mallakar mai hanawa na tyrosine kinase mai karɓa na baka (RTK) kuma yana iya hana aikin kinase na ƙwararrun ƙwararrun ƙwararrun jijiyoyi (VEGF) masu karɓar VEGFR1 ( FLT1), VEGFR2 (KDR), da VEGFR3 (FLT4).Lenvatinib kuma zai iya hana shigar da sauran RTKs a cikin angiogenesis na pathological, ci gaban tumo, da ci gaban ciwon daji sai dai don ayyukan salula na yau da kullum ciki har da masu karɓar fibroblast girma factor (FGF) FGFR1, 2, 3, da 4;Mai karɓar haɓakar haɓakar platelet (PDGFR [alpha]), KIT, da RET.[Alamomi]: Lenvatinib ya dace da maganin marasa lafiya na ciwon daji na thyroid na sake dawowa gida ko nau'in metastasis, nau'in ci gaba da nau'in rediyoaktif-refractory daban-daban.Ranar 13 ga Fabrairu, 2015, FDA ta Amurka ta amince da Lenvatinib na maganin ciwon daji don maganin ciwon daji na thyroid.Lenvatinib shine mai hanawa enzyme mai yawan manufa, yana da ikon hana VEGFR2 da VEGFR3 (mai karɓar haɓakar haɓakar haɓakar ƙwayoyin jijiyoyi).Sunan kasuwancin Lenvatinib shine Lenvima.A ranar 20 ga Mayu, 2015, Hukumar Kula da Magunguna ta Turai (EMA) ta amince da Lenvatinib don maganin cutar daji, ci gaba a cikin gida ko metastatic bambanta (papillary, follicular, nau'in Hurthle) ciwon daji na thyroid (DTC).A cikin gwajin, lokacin rayuwa na tsaka-tsaki ga marasa lafiya na rediyoaktif iodine-refractory DTC da aka yi wa Lenvatinib ya kasance watanni 18 yayin da ƙimar marasa lafiya da ke ɗaukar placebo shine watanni 3 kawai.
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Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8...
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Lenvatinib Mesylate CAS 857890-39-2 Assay 98.0~...
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Desquinolinyl Lenvatinib CAS 796848-79-8 Tsaftace ...
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4-Amino-3-Chlorophenol CAS 17609-80-2 Lenvatini...
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4-Amino-3-Chlorophenol Hydrochloride CAS 52671-...
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4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 4...
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Lenvatinib Mesylate Intermediate CAS 15568-85-1...
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Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylat...
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Lenvatinib Mesylate Intermediate CAS 205448-65-...