Methyl (S)-2-(Boc-amino) -3-[(S) -2-oxo-3-pyrrolidinyl] propanoate CAS 328086-60-8 PF-07321332 Boceprevir Intermediate

Takaitaccen Bayani:

Sunan Chemical: Methyl (S)-2-(Boc-amino) -3-[(S) -2-oxo-3-pyrrolidinyl] propanoate

Saukewa: 328086-60

Bayyanar: Fari zuwa Kashe-fari foda

Matsakaicin PF-07321332 Paxlovid (CAS 2628280-40-8) da Boceprevir (CAS 394730-60-0)

Kyakkyawan inganci, Samar da Kasuwanci

Inquiry: alvin@ruifuchem.com

Aika mana imel

Cikakken Bayani

Samfura masu dangantaka

Tags samfurin

Bayani:

Samar da Kasuwanci PF-07321332 Matsakaici masu alaƙa da Paxlovid tare da Babban inganci
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(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-Carboxylic Acid Methyl Ester Hydrochloride 565456-77-1
Methyl (S)-2-(Boc-amino) -3-[(S) -2-oxo-3-pyrrolidinyl] propanoate CAS 328086-60-8
6,6-Dimethyl-3-azabicyclo[3.1.0] hexane CAS 943516-54-9

Abubuwan Sinadarai:

Sunan Sinadari	Methyl (S)-2-(Boc-amino)-3-[(S) -2-oxo-3-pyrrolidinyl] propanoate
Makamantu	Methyl (S)-2-((tert-butoxycarbonyl)amino) -3-((S) -2-oxopyrrolidin-3-yl) propanoate;(αS,3S) -α- [(tert-Butyloxycarbonyl) aMino] -2-oxo-3-pyrrolidinepropanoic acid Methyl Ester;(S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-((S)-2-oxopyrrolidin-3-yl) propanoate
Lambar CAS	328086-60-8
Lambar CAT	Saukewa: RF-PI317
Matsayin Hannun jari	A Hannun jari, Ma'aunin Samfuran Har zuwa Daruruwan Kilogram
Tsarin kwayoyin halitta	Saukewa: C13H22N2O5
Nauyin Kwayoyin Halitta	286.33
Alamar	Ruifu Chemical

Ƙayyadaddun bayanai:

Abu	Ƙayyadaddun bayanai
Bayyanar	Fari zuwa Kashe-Farin Foda
Identification A	IR: Mai kama da Abun Magana
Identity B	Lokacin Tsayawa: Kama da Abun Magana
Asara akan bushewa	≤1.0%
Ragowa akan Ignition	≤0.20%
Tsaftace Guda Daya	≤0.50%
Jimlar ƙazanta	≤2.0%
Karfe masu nauyi (Pb)	≤20ppm
Tsafta	≥98.0%
Matsayin Gwaji	Matsayin Kasuwanci
Amfani	Matsakaicin PF-07321332 Paxlovid (CAS 2628280-40-8) da Boceprevir (CAS 394730-60-0)

Kunshin & Ajiya:

Kunshin: Bottle, Aluminum tsare jakar, Kwali drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.

Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.

Amfani:

FAQ:

Aikace-aikace:

Methyl (S) -2- (Boc-amino) -3- [(S) -2-oxo-3-pyrrolidinyl] propanoate (CAS 328086-60-8) shine matsakaici na PF-07321332 Paxlovid (CAS 2628280-40) -8) da Boceprevir (CAS 394730-60-0).PF-07321332, babban ɓangaren Paxlovid (PF-07321332 da Ritonavir) wanda shine ɗan takarar bincike na COVID-19 na baka, shine mai hana 3C-kamar protease (3CLPRO) na baki tare da tasirin antiviral akan kwayar cutar SARS-CoV-2. da COVID-19.A ranar 6 ga Nuwamba, 2021, Pfizer ya ba da sanarwar cewa Paxlovid ya ragu sosai a asibiti da mutuwa, bisa ga wani bincike na wucin gadi na Mataki na 2/3 EPIC-HR (Kimanin Hana Protease don COVID-19 a cikin Marasa Lafiya Masu Haɗari) bazuwar, binciken makafi biyu. na manya marasa lafiya marasa asibiti tare da COVID-19, waɗanda ke cikin haɗarin ci gaba zuwa rashin lafiya mai tsanani.Boceprevir (EBP-520) shine mai hana HCV protease inhibitor (Ki=14 nM) don maganin kamuwa da cutar hanta.Boceprevir tare da pegylated interferon da ribavirin (PegIFN/RBV) sun ba da damar haɓakawa a cikin ƙimar amsawar ƙwayoyin cuta na marasa lafiya tare da genotype 1 HCV.Boceprevir yana hulɗa tare da maganin rigakafi (IT) ta hanyar hana cytochrome P450 3A enzyme.