N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1 Tsarkake>99.0% (HPLC) Afatinib Dimaleate Matsakaici Factory Featured Image

N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1 Tsarkake>99.0% (HPLC) Afatinib Dimaleate Tsakanin Factory

Takaitaccen Bayani:

Sunan Kemikal: N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine

Saukewa: 162012-67-1

Tsafta:> 99.0% (HPLC)

Bayyanar: Rawaya Mai Haske zuwa Fada Rawaya

Matsakaicin Afatinib Dimaleate (CAS: 850140-73-7)

E-Mail: alvin@ruifuchem.com

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Bayani:

Ruifu Chemical Supply Intermediates of Afatinib
Afatirib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino) acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H) -daya CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl) oxy) quinazoline-4,6-DiamineSaukewa: CAS314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy) quinazolin-4-AmineSaukewa: CAS314771-88-5

Abubuwan Sinadarai:

Sunan Sinadari	N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine
Makamantu	N- (3-Chloro-4-Fluorophenyl) -7-Fluoro-6-Nitro-4-Quinazolinamine;(3-Chloro-4-Fluorophenyl) (7-Fluoro-6-Nitroquinazolin-4-yl) amin;4- (3-Chloro-4-Fluoroanilino) -7-Fluoro-6-Nitroquinazoline;Afatinib Intermediate A
Lambar CAS	162012-67-1
Lambar CAT	Saukewa: RF-PI2026
Matsayin Hannun jari	A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton
Tsarin kwayoyin halitta	Saukewa: C14H7ClF2N4O2
Nauyin Kwayoyin Halitta	336.68
Hankali	Hankalin iska, Mai jin zafi
Matsayin narkewa	242.0 ~ 244.0 ℃
Wurin Tafasa	489 ℃
Yawan yawa	1.616
Alamar	Ruifu Chemical

Ƙayyadaddun bayanai:

Abu	Ƙayyadaddun bayanai
Bayyanar	Rawaya Mai Haske zuwa Foda Rawaya
Tsarkake / Hanyar Bincike	> 99.0% (HPLC)
Asara akan bushewa	<0.50%
Ragowa akan Ignition	<0.20%
Abubuwa masu alaƙa
Rashin Tsabtace Mutum	<0.50%
Jimlar ƙazanta	<1.00%
Karfe masu nauyi	≤20ppm
Infrared Spectrum	Yayi daidai da Tsarin
Abubuwan da aka bayar na Proton NMR Spectrum	Yayi daidai da Tsarin
Matsayin Gwaji	Matsayin Kasuwanci
Amfani	Matsakaicin Afatinib Dimaleate (CAS: 850140-73-7)

Kunshin & Ajiya:

Kunshin: Bottle, Aluminum tsare jakar, 25kg / kwali Drum, ko bisa ga abokin ciniki ta bukata

Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi

Amfani:

FAQ:

Aikace-aikace:

N- (3-Chloro-4-Fluorophenyl) -7-Fluoro-6-Nitroquinazolin-4-Amine (CAS: 162012-67-1) matsakaici ne a cikin haɗin Afatinib Dimaleate (CAS: 850140-73-7) .Afatinib Dimaleate wani nau'in gishiri ne na Afatinib.Afatinib ƙarni na biyu ne, ana gudanar da baki, mai hanawa mara jurewa na dangin ErbB na tyrosine kinases.Mechanism of ActionAfatinib ya saukar da siginar ErbB ta hanyar haɗin gwiwa tare da sassan kinase na mai karɓar haɓakar haɓakar haɓakar epidermal (EGFR), mai karɓar haɓakar haɓakar haɓakar ɗan adam (HER) 2 da HER4, wanda ke haifar da hanawa na tyrosine kinase autophosphorylation;Hakanan yana hana transphosphorylation na HER3.An amince da Afatinib a matsayin monotherapy don maganin EGFR tyrosine kinase inhibitor (TKI) - manya masu butulci tare da ci gaba na gida ko DefinitionChEBI: Gishiri na namiji da aka samu ta hanyar hada afatinib tare da nau'ikan molar guda biyu na maleic acid.An yi amfani da shi don jiyya na farko na marasa lafiya tare da ciwon huhu na huhu wanda ba ƙananan ƙananan ƙwayoyin cuta ba.