N-Acetyl-L-Tyrosine CAS 537-55-3 (Ac-Tyr-OH; NALT) Assay 99.0 ~ 101.0 Factory
Shanghai Ruifu Chemical Co., Ltd. shine babban masana'anta kuma mai ba da kaya na N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) tare da babban inganci.Ruifu Chemical yana ba da jerin amino acid da abubuwan da aka samo asali.Babban samfuri mai inganci, farashi mai ma'ana, kyakkyawan aiki da sauri bayan-tallace-tallace sune alkawurran Ruifu Chemical ga abokan ciniki.Za mu iya samar da COA, isarwa a duniya, ƙanana da yawa da ake samu.Idan kuna sha'awar N-Acetyl-L-Tyrosine,Please contact: alvin@ruifuchem.com
Sunan Sinadari | N-Acetyl-L-Tyrosine |
Makamantu | Ac-Tyr-OH;AC-L-Tyr-OH;N-Ac-L-Tyr;NALT;Ac-Tyrosine;Acetyltyrosine;N-Acetyltyrosine;Acetyl-Laevo-Tyrosine;LN-Acetyltyrosine;(2S) -2- (Acetylamino) -3- (4-Hydroxyphenyl) Propanoate;(S) -2-Acetamido-3- (4-Hydroxyphenyl) Propanoic Acid;N-Acetyl-(S)-2-Amino-3- (4-Hydroxyphenyl) Propionic Acid;(2S) -2-(Acetylamino) -3- (4-Hydroxyphenyl) Propanoic Acid |
Matsayin Hannun jari | A Hannun jari, Ƙarfin Samar da Ton 30 a kowace shekara |
Lambar CAS | 537-55-3 |
Tsarin kwayoyin halitta | Saukewa: C11H13NO4 |
Nauyin Kwayoyin Halitta | 223.23 g/mol |
Matsayin narkewa | 150.0 zuwa 154.0 ℃ |
Yawan yawa | 1.304 |
Ruwan Solubility | Mai narkewa a cikin Ruwa, Kusan Gaskiya |
Adana Yanayin. | An rufe shi a bushe, Ajiye a Zazzabin ɗaki |
COA & MSDS | Akwai |
Rabewa | Amino Acids & Abubuwan Samfura |
Alamar | Ruifu Chemical |
Lambobin haɗari | Xi - Haushi | F | 10 |
Bayanin Hatsari | 41-36/37/38 | Farashin TSCA | Ee |
Bayanan Tsaro | 26-39-36 | HS Code | 2922491990 |
WGK Jamus | 3 |
Abubuwa | Ka'idojin dubawa | Sakamako |
Bayyanar | Farin lu'ulu'u ko lu'ulu'u ko foda | Ya dace |
Ganewa | Infrared Absorption Spectrum | Ya dace |
Takamaiman Juyawa [α] 20/D | +46.5° zuwa +49.0°(C=2 a cikin H2O) | + 47.2 ° |
Yanayin Magani (Transmittance) | ≥96.0% | 98.3% |
Chloride (Cl) | ≤0.020% | <0.020% |
Sulfate (SO4) | ≤0.020% | <0.020% |
Ammonium (NH4) | ≤0.020% | <0.020% |
Iron (F) | ≤30ppm | <30ppm |
Karfe masu nauyi (Pb) | ≤10ppm | <10ppm |
Arsenic (As2O3) | ≤2.0pm | <2.0pm |
Tyrosine | ≤1.00% | Ya dace |
Asara akan bushewa | ≤0.50% | 0.25% |
Ragowa akan ƙonewa (Sulfated) | ≤0.10% | 0.07% |
Assay | 99.0 zuwa 101.0% | 99.5% |
pH darajar | 2.0 zuwa 3.0 | 2.3 |
Kammalawa | Haɗu da Ma'auni na AJI97, USP35 | |
Babban Amfani | Kariyar Abinci;Abubuwan Abincin Abinci;Matsakaicin Magunguna |
N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) Hanyar Gwajin AJI97
N-Acetyl-L-Tyrosine, idan aka bushe, ya ƙunshi bai wuce kashi 99.0 ba kuma bai wuce kashi 101.0 na N-Acetyl-L-Tyrosine (C11H13NO4).
Bayani: Farin lu'ulu'u ko lu'ulu'u na lu'ulu'u ko lu'u-lu'u, ɗanɗano mai ƙarfi acid
Mai narkewa cikin ruwa.
Solubility (H2O, g/100g): 17.5 (20 ℃), 72.4 (40 ℃), 158 (60 ℃)
Ganewa: Kwatanta nau'in infrared na samfurin tare da ma'auni ta hanyar fayafai bromide.
Takamaiman Juyawa [α] 20/D: Samfurin Busasshen, C=4, H2O
Halin Magani (Mai watsawa): 0.5g a cikin 10ml na H2O, spectrophotometer, 430nm, 10mm kauri.
Chloride (Cl): 0.7g, A-1, ref: 0.40ml na 0.01mol/L HCl
Ammonium (NH4): B-1
Sulfate (SO4): 1.2g, (1), ref: 0.50ml na 0.005mol/L H2SO4
Iron (Fe): 0.5g, Ref: 1.5ml na Iron Std.(0.01mg/ml)
Karfe masu nauyi (Pb): 2.0g, (3), Ref: 2.0ml na Pb Std.(0.01mg/ml)
Arsenic (As2O3): 1.0g, (1), ref: 2.0ml na As2O3 Std.
Asarar bushewa: a 105 ℃ na 3 hours
Residue on Ignition (Sulfated): AJI Test 13
Gwajin: samfurin busassun, 300mg, (1), 40ml H2O, (2), 0.1mol/L NaOH, 1ml=22.323mg C11H13NO4
Tyrosine: Liquid chromatography.Yanayin aiki: Mai ganowa: UV mai ɗaukar hoto (214nm);Tushen: ODS, 4.6mm x 150mm;Zazzabi na ginshiƙi: zafin ɗaki.Yawan kwarara: 1ml/min;Lokacin wayar hannu: 0.04mol/L maganin monopotassium phosphate (pH 4.35): methanol (193: 3)
pH: 1.25g a cikin 50ml na H2O
Ƙayyadaddun ma'auni da yanayin da aka ba da shawarar: Tsayayyen kwantena a zafin dakin da aka sarrafa (shekaru 2).
N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) Hanyar Gwajin USP35
BAYANI
N-Acetyltyrosine ya ƙunshi NLT 98.5% da NMT 101.0% na C11H13NO4, kamar yadda N-Acetyl-L-Tyrosine, ƙididdiga akan busasshen tushe.
GANO
A. RASHIN NUTSUWA <197K>
B. JUYAWAR gani, Jujjuya ta musamman <781S>
Samfurin bayani: 10 mg/ml
Sharuɗɗan karɓa: NLT +46.0° da NMT +49.0°, an ƙaddara a 20°
C. Ƙimar RF na babban tabo na Samfurin Magani a cikin gwaji don Najasa Kwayoyin Halitta yayi daidai da na daidaitaccen bayani 1.
ASSAY
TSARI
Maganin samfurin: Narkar da kusan MG 180 na N-Acetyltyrosine, wanda aka auna, a cikin 50 ml na ruwa mara kyau na carbon dioxide.
Titrimetric tsarin
(Duba Titrimetry <541>)
Yanayin: Kai tsaye titration
Titrant: 0.1 N sodium hydroxide VS
Gano ƙarshen ƙarshen: Potentiometric
Daidaitawa: Kowane ml na 0.1 N sodium hydroxide VS daidai yake da 22.32 MG na C11H13NO4.
RASHIN ZUCIYA
Najasa Na Inorganic
RASHIN WUTA <281>: NMT 0.1%
CLORIDE DA SULFATE, Chloride <221> NMT 200 ppm.Wani yanki na 0.7-g yana nuna babu ƙarin chloride fiye da daidai da 0.40 ml na 0.01 N hydrochloric acid.
CHLORIDE DA SULFATE, Sulfate <221> NMT 200 ppm.Wani yanki na 1.2-g yana nuna babu sauran sulfate fiye da daidai da 0.25 ml na 0.020 N sulfuric acid.
IRON <241>: NMT 20ppm
KARFE MAI KYAU, Hanyar I <231>: NMT 10ppm
Najasa Na Halitta
TSARI
Adsorbent: 0.25-mm Layer na chromatographic silica gel cakuda
Daidaitaccen bayani na 1: 8 mg/mL na USP N-Acetyl-L-tyrosine RS a cikin cakuda ruwa, glacial acetic acid, da barasa (3:3:94)
Daidaitaccen bayani 1: Tsarma daidaitaccen bayani na hannun jari 1 tare da barasa don samun maganin da ke da sananniya na kusan 0.4 mg/mL
Daidaitaccen bayani 2: 0.8 mg / ml na USP L-Tyrosine RS narkar da a cikin cakuda glacial acetic acid da ruwa (1: 1), kuma diluted da barasa.
Samfurin bayani: Canja wurin 0.8 g na N-Acetyltyrosine zuwa 10-mL volumetric flask, narke a cikin 6 ml na cakuda glacial acetic acid da ruwa (1: 1), kuma tsarma da barasa zuwa girma.
Girman aikace-aikacen: 5µL
Haɓaka tsarin narkewa: cakuda ammonia da 2-propanol (3: 7)
Fesa reagent: Narke 0.2 g na ninhydrin a cikin 100 ml na cakuda butanol da 2 N acetic acid (95:5).
Dacewar tsarin
Bukatun dacewa: chromatogram na tsarin dacewa da tsarin yana nuna aibobi biyu a sarari.
Bincika: Ci gaba kamar yadda aka umarce shi don Chromatography <621> Chromatography na bakin-Layer.Bayan bushewar farantin iska, maimaita tsarin ci gaba.Bayan bushewar iska a karo na biyu, fesa da Reagent Fesa, kuma zafi tsakanin 100 ° da 105 ° na kimanin minti 15.
Sharuɗɗan karɓa: Duk wani wuri na biyu na samfurin samfurin bai fi girma ko mafi tsanani fiye da ainihin tabo na Standard Solution1 ba, sai dai tabo daidai da tyrosine, wanda bai fi girma ko mafi tsanani fiye da babban tabo daga daidaitaccen bayani 2.
Najasa ɗaya: NMT 0.5%
Iyakar tyrosine: NMT 1.0%
MAKAMMAN JARRABAWA
RASHIN RASHI <731>: bushe samfurin a 105 ℃ na 3 h: yana rasa NMT 0.1% na nauyinsa.
KARIN BUKATA
KYAUTA DA ARJIYA: Ajiye a cikin kwantena da aka rufe sosai, kuma a adana a zazzabi na ɗaki mai sarrafawa.
MATSAYIN NAZARI NA USP <11>
USP N-Acetyl-L-tyrosine RS
USP L-Tyrosine RS
Yadda ake siya?Da fatan za a tuntuɓiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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Ayyuka & Aikace-aikacen N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) foda
1. N-Acetyl-L-Tyrosine asalin acetyl ne daga amino acid, L-tyrosine.Yana iya narkewa cikin ruwa idan aka kwatanta da L-tyrosine kuma ana amfani da shi azaman kari na abinci na mahaifa.N-Acetyl-L-Tyrosine, wani barga kuma mafi soluble nau'i na tyrosine, an haɗa shi a cikin wasu samfuran amino acid na parenteral na kasuwanci a halin yanzu kamar TrophAmine da Aminosyn-II.
2. N-Acetyl-L-Tyrosine yana shiga cikin samar da catecholamine.Ana iya amfani da shi azaman ɓangaren watsa labarai na al'adar tantanin halitta a cikin kasuwancin bioomanufacture na furotin da ke sake haɗuwa da warkewa da ƙwayoyin rigakafi na monoclonal.
3. N-Acetyl-L-Tyrosine yana da mahimmancin amino acid, wanda shine nau'in abinci mai mahimmanci ga jikin mutum da dabba, girma da ci gaba yana taka muhimmiyar rawa, ana iya amfani dashi a abinci, magunguna da dai sauransu.
4. N-Acetyl-L-Tyrosine taka muhimmiyar rawa a cikin kira na dopamine da sauran hormones a cikin jikinka.Yana iya haɓaka matakan neurotransmitters dopamine, norepinephrine da epinephrine.Yana taimakawa wajen tallafawa manyan matakan mayar da hankali da aikin fahimi.Zai iya ƙara ƙwaƙwalwar aiki da jin daɗin jin daɗi.
5. N-Acetyl-L-Tyrosine an canza shi daga al'ada Tyrosine saboda yana dauke da ƙarin acetic acid.Wannan a zahiri yana taimakawa wajen ƙara haɓakar abubuwan da ke cikin fili ta yadda zai fi dacewa da shi kai tsaye cikin jini.
6. N-Acetyl-L-Tyrosine wani nau'i ne na L-Tyrosine na bioavailable sosai don maganin precursor na halitta na ƙananan yanayi N-Acetyl-L-Tyrosine za a iya amfani dashi a cikin ƙananan allurai fiye da L-Tyrosine.L-Tyrosine na al'ada ba shi da kwanciyar hankali kuma ba ya narkewa a cikin ruwa, wanda zai iya haifar da raguwar bioavailability.
7. N-Acetyl-L-Tyrosine yana haɓaka solubility da kwanciyar hankali yana sa shi zama mafi saurin shanyewa da nau'in amino acid L-Tyrosine wanda ba shi da saurin fitar da fitsari.
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