N-Hydroxysuccinimide (HOSu) CAS 6066-82-6 Haɗaɗɗen Reagent Tsabta> 99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. shine babban kamfani na N-Hydroxysuccinimide (HOSu) (CAS: 6066-82-6) tare da babban inganci.Ruifu Chemical yana ba da jerin abubuwan kariya da reagents masu haɗawa.Ruifu na iya samar da isar da saƙo na duniya, farashi mai gasa, ƙanana da yawa da ake samu.Sayi N-Hydroxysuccinimide,Please contact: alvin@ruifuchem.com
Sunan Sinadari | N-Hydroxysuccinimide |
Makamantu | HOSU;NHS;1-Hydroxysuccinimide;1-Hydroxy-2,5-Pyrrolidinedione;N-Hydroxy-2,5-dioxopyrrolidine |
Matsayin Hannun jari | A Stock, Mass Production |
Lambar CAS | 6066-82-6 |
Tsarin kwayoyin halitta | Saukewa: C4H5NO3 |
Nauyin Kwayoyin Halitta | 115.09 g/mol |
Matsayin narkewa | 93.0 ~ 98.0 ℃ (lit.) |
Yawan yawa | 1.649 |
M | Hygroscopic.Zafi Sensitive, Danshi Sensitive |
Solubility a Dioxane | Mai narkewa a Dioxane, Kusan Fasikanci |
Solubility a cikin Ruwa | Mai narkewa a cikin Ruwa |
Adana Yanayin. | Wuri Mai sanyi & Busassun wuri (2 ~ 8 ℃) |
COA & MSDS | Akwai |
Kashi | Haɗin kai Reagents |
Alamar | Ruifu Chemical |
Abubuwa | Ka'idojin dubawa | Sakamako |
Bayyanar | Farin Crystalline Foda | Ya bi |
Matsayin narkewa | 93.0 ~ 98.0 ℃ | 94.0 ~ 97.0 ℃ |
Asara akan bushewa | <0.50% | 0.15% |
Tsarkake / Hanyar Bincike | > 99.0% (HPLC) | 99.5% |
Infrared Spectrum | Yayi daidai da Tsarin | Ya bi |
Abubuwan da aka bayar na Proton NMR Spectrum | Yayi daidai da Tsarin | Ya bi |
Kammalawa | An gwada samfurin kuma ya dace da ƙayyadaddun bayanai |
Lokacin wayar hannu: 0.1% maganin phosphoric acid: acetonitrile = 90:10
Tsawon tsayi: 220nm
Yawan gudu: 1ml/min
Kunshin:Bottle, Aluminum tsare jakar, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Danshi mai hankali.Ajiye a cikin kwantena da aka rufe a wurin sanyi da bushe (2 ~ 8 ℃) nesa da abubuwan da ba su dace ba.Kare daga haske da danshi.
Jirgin ruwa:Bayarwa ga duniya ta FedEx / DHL Express.Bayar da isarwa cikin sauri kuma abin dogaro.
Yadda ake siya?Da fatan za a tuntuɓiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Kwarewar Shekaru 15?Muna da fiye da shekaru 15 na gwaninta a cikin ƙira da fitarwa na matsakaicin matsakaicin magunguna masu inganci ko sinadarai masu kyau.
Manyan Kasuwanni?Sayarwa zuwa kasuwannin cikin gida, Arewacin Amurka, Turai, Indiya, Koriya, Jafananci, Australia, da sauransu.
Fa'idodi?Babban inganci, farashi mai araha, sabis na ƙwararru da tallafin fasaha, bayarwa da sauri.
inganciTabbaci?Tsananin kula da ingancin inganci.Kayan aikin ƙwararru don bincike sun haɗa da NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, gwajin ƙayyadaddun ƙwayoyin cuta, da sauransu.
Misali?Yawancin samfurori suna ba da samfurori kyauta don ƙima mai kyau, farashin jigilar kaya ya kamata a biya ta abokan ciniki.
Binciken Masana'antu?Ma'aikata duba maraba.Da fatan za a yi alƙawari a gaba.
MOQ?Babu MOQ.Karamin tsari abin karɓa ne.
Lokacin Bayarwa? Idan cikin hannun jari, garantin isar da kwana uku.
Sufuri?By Express (FedEx, DHL), ta Air, ta Teku.
Takardu?Bayan sabis na tallace-tallace: COA, MOA, ROS, MSDS, da dai sauransu za a iya ba da su.
Haɗin Kan Al'ada?Zai iya ba da sabis na haɗawa na al'ada don dacewa da buƙatun bincikenku.
Sharuɗɗan Biyan kuɗi?Za a fara aiko da daftari na Proforma bayan tabbatar da oda, an rufe bayanan bankin mu.Biya ta T/T (Telex Transfer), PayPal, Western Union, da dai sauransu.
Alamomin haɗari Xi - Haushi
Lambobin haɗari
36/37/38 - Haushi da idanu, tsarin numfashi da fata.
Bayanin Tsaro
S22 - Kar a shaka kura.
S24/25 - Guji hulɗa da fata da idanu.
S26 - Idan ana hulɗa da idanu, kurkura nan da nan da ruwa mai yawa kuma ku nemi shawarar likita.
S36 - Sanya tufafin kariya masu dacewa.
WGK Jamus 3
TSCA da
Lambar 2925190090
Hazard Note Irritant
N-Hydroxysuccinimide (HOSu) (CAS: 6066-82-6), reagent don shirye-shiryen esters masu aiki na amino acid.Peptide m lokaci kira hade wakili.
Ana amfani da N-Hydroxysuccinimide sau da yawa don taimakawa carbodiimide-matsakaicin tsaka-tsakin peptide haɗin gwiwa ta hanyar samar da tsaka-tsakin ester mai aiki ta hanyar haɓakar ƙungiyar carboxyl surface da NHS.Matsakaicin ester na NHS-reactive yana da saukin kamuwa da harin nucleophilic ta amines na farko kuma yana haifar da samuwar bargawar amide tsakanin saman biomaterial da N-terminus na peptide.
N-Hydroxysuccinimide shine succinimide na hydroxylated wanda ake amfani dashi sosai a cikin kunna acid carboxylic zuwa NHS-esters don haɓaka haɗin gwiwa tare da nucleophiles.Ana amfani da wannan hanyar da aka fi amfani da ita wajen kunna nau'ikan acid kyauta na fluorophores don haɓaka haɗuwa da waɗannan fluorophores zuwa ragowar furotin amine.An kuma bayyana amfani da kunnawar ester na NHS a cikin haɗin amino acid N-acyl.
An yi amfani da shi don kira na amino acid protectant, Semi-synthetic kanamycin da Pharmaceutical intermediates.N-hydroxybutyldiimide da abubuwan da suka samo asali ne da muhimmanci albarkatun kasa don kira na peptides, maganin rigakafi, amino acid da sunadarai.N-hydroxybutyldiimide da ake amfani a cikin shirye-shiryen na aiki aiki. esters, da kuma hana tasirin aiki na gani na peptide coupling yana da fa'idar AMFANIN a cikin magani, kuma shine ainihin albarkatun sinadarai.
Ana amfani da N-Hydroxysuccinimide don ingantattun amidations a cikin hanyar carbodiimide.Hakanan ana amfani dashi don kunna ƙungiyar carboxyl kuma yana amsawa tare da amine don samar da amide.Yana da hannu a cikin shirye-shiryen N-hydroxymaleimide-styrene copolymer.
An shirya N-Hydroxysuccinimide kamar haka: 100g (1.0mol) succinic anhydride da 70g (1.0mol) na hydroxylamine hydrochloride suna mai tsanani tare, ana kiyaye tsarin amsawa a ƙarƙashin mummunan matsa lamba don cire abubuwan da aka haifar, kuma yana da sauri mai tsanani zuwa sama da 125 ℃. , sannan a hankali yana tashi zuwa 160 ℃ bayan 1H.An dakatar da dumama kuma lokacin da zafin jiki ya ragu zuwa 125 ℃, an zubar da maganin ruwa a cikin diethyl ether kuma an motsa shi da ƙarfi.Bayan da samfurin ya warke, da ether Layer da aka decanted, da warke samfurin aka mai tsanani zuwa tafasa da 400ml na butanol, zafi tace, da kuma tace da sauri sanyaya zuwa 0 ℃.Bayan tacewa na 1H, an wanke lu'ulu'u a jere tare da butanol da diethyl ether, kuma samfurin da aka samu ya sake yin recrystallized daga ethyl acetate don samun 50g na gama samfurin a cikin 44% yawan amfanin ƙasa.