Octreotide Acetate CAS 83150-76-9 Peptide Tsabta (HPLC) ≥98.0% API Babban Ingancin

Octreotide Acetate (Sandostatin) shine analog na peptide na roba na hormone somatostatin, analog na somatostatin na dogon lokaci wanda aka nuna don sarrafa alamun alamun acromegaly da ciwan ciki na gastroenteropancreatic.Sauran yuwuwar amfani da ke ƙarƙashin bincike sun haɗa da ciwon sukari, psoriasis da cutar Alzheimer.Octreotide acetate (Sandostatin) shine analog na peptide na roba na hormone somatostatin.Ayyukansa sun haɗa da hanzarin ƙwayar ƙwayar ƙwayar cuta da hanzarin ƙwayar ƙwayar ƙwayar ƙwayar cuta da Glucagon.Ba kamar somatostatin ba, wanda ke da rabin rayuwar plasma na 'yan mintuna kaɗan, Octreotide yana da kawar da rabin rayuwar sa'o'i 1 zuwa 2.Fitar da miyagun ƙwayoyi ne da farko na koda.Octreotide yana rage motsin ciki kuma yana hana kumburin gallbladder.

Magungunan Peptide Novartis Sandostatin (Octreotide Acetate), wani nau'in nau'in somatostatin octapeptide na roba ne na halitta, yana riƙe da tasirin magunguna kamar na somatostatin, kuma tasirin yana daɗewa.Alamomi ga Octreotide Acetate sun haɗa da acromegaly;Rage bayyanar cututtuka da alamun da ke hade da aikin gastroenteropancreatic endocrine neoplasia;Kuma inganci a cikin Ciwon daji na Carcinoid wanda ke gabatar da ciwon carcinoid, ciwace-ciwacen VIP, da ciwan glucagon.Bugu da ƙari, Octreotide Acetate don gastrinomas / Zollinger-Ellison ciwo (yawanci a hade tare da proton pump inhibitors ko H2 receptor blockers), Insulinomas (rigakafin farko na hypoglycemia da kiyaye sukarin jini na al'ada), ƙimar haɓakar haɓakar haɓakar haɓakar ƙwayar cuta. kusan 50%.

Octreotide Acetate magani ne na inshorar lafiya na ƙasa na Class B, wanda shine asalin octapeptide na halitta na somatostatin, idan aka kwatanta da somatostatin na halitta, rabin rayuwar somatostatin a bayyane yake tsawaita kuma yana da tasirin magunguna iri ɗaya, gami da hana aikin hormone girma, hanawa. na acid gastric, pancreatic enzyme, glucagon da insulin secretion, da raguwar kwararar jini na visceral, raguwar motsin ciki.Idan aka kwatanta da somatostatin na asali, octreotide yana da tsawon rabin rayuwa, ya fi zaɓi don hana haɓakar haɓakar hormone girma fiye da hana fitar da insulin, kuma baya haifar da sake dawowa hypersecretion na hormone.1, Sarrafa tiyata ko radiation far ba zai iya isasshe sarrafa cutar a marasa lafiya da acromegaly bayyanar cututtuka da kuma rage haƙuri girma hormone (GH) insulin-kamar girma factor -1 (1GF-1) plasma matakan.Ana iya amfani da Sandostatin don kula da marasa lafiya tare da acromegaly waɗanda ba za su iya ko ba su son yin tiyata, ko kuma kula da marasa lafiya tare da acromegaly waɗanda ba su riga sun sami maganin radiation ba.2. Rage bayyanar cututtuka da ke hade da ciwon daji na gastroenteropancreatic (GEP) na aikin endocrin kamar ciwon daji na carcinoid tare da bayyanar cututtuka na carcinoid.Sandostatin ba maganin ciwon daji ba ne kuma baya warkar da waɗannan marasa lafiya.3, Rigakafin matsalolin bayan tiyatar pancreatic.4, Hanta cirrhosis marasa lafiya da ciwon ciki-esophageal variceal zub da jini lalacewa ta hanyar gaggawa magani, hemostasis da rigakafin rebleeding, Sandostatin ya kamata a hade tare da endoscopic sclerotherapy da sauran musamman magani.