Matsakaicin Olopatadine Hydrochloride CAS 27710-82-3 Tsarkake>99.0% (HPLC)
Jagoran Mai Kawo na Olopatadine Hydrochloride Intermediates
Olopatadine Hydrochloride CAS 140462-76-6
Isoxepac CAS 55453-87-7
[3- (Dimethylamino) propyl] triphenylphosphonium Bromide Hydrobromide CAS 27710-82-3
Please Contact: alvin@ruifuchem.com
| Sunan Sinadari | [3- (Dimethylamino) propyl] triphenylphosphonium Bromide Hydrobromide |
| Makamantu | (3-Dimethylaminopropyl) triphenylphosphonium Bromide HBr |
| Lambar CAS | 27710-82-3 |
| Lambar CAT | Saukewa: RF2698 |
| Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
| Tsarin kwayoyin halitta | Saukewa: C23H28Br2NP |
| Nauyin Kwayoyin Halitta | 509.27 |
| Matsayin narkewa | 283.0 ~ 285.0 ℃ |
| Kwanciyar hankali | Hygroscopic |
| Solubility | Chloroform (Dan kadan), methanol (Dan kadan) |
| Alamar | Ruifu Chemical |
| Abu | Ƙayyadaddun bayanai |
| Bayyanar | Fari zuwa Kashe-Farin Crystal Foda |
| Tsarkake / Hanyar Bincike | > 99.0% (HPLC) |
| Hanyar Assay / Analysis | >99.0% (Titration) |
| Asara akan bushewa | <0.50% |
| Tsaftace Guda Daya | <0.50% |
| Jimlar ƙazanta | <1.00% |
| 1 H NMR Spectrum | Daidaita Da Tsarin |
| Matsayin Gwaji | Matsayin Kasuwanci |
| Amfani | Matsakaicin Olopatadine Hydrochloride (CAS: 140462-76-6) |
Kunshin: Bottle, Aluminum tsare jakar, 25kg / kwali Drum, ko bisa ga abokin ciniki ta bukata
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[3- (Dimethylamino) propyl] triphenylphosphonium Bromide Hydrobromide (CAS: 27710-82-3) shine matsakaici na Olopatadine Hydrochloride (CAS: 140462-76-6).Olopatadine Hydrochloride magani ne na rashin lafiyan jiki.Yana da tasirin dual na hana sakin histamine da zaɓin adawa da masu karɓar HI, kuma ba shi da hanawar tsarin juyayi na tsakiya da cututtukan cututtukan zuciya masu guba waɗanda ke da alaƙa da magungunan HI receptor antagonist antiallergic kwayoyi.Olopatadine Hydrochloride ba zai iya hana sakin histamine kawai daga kwayoyin mast ba, amma har ma da masu karɓa na H1 da zaɓaɓɓu, kuma ba shi da wani tasiri akan α adrenergic receptors, dopamine receptors, da M1 da M2 masu karɓa.Daga cikin su, sakamako masu illa na tsarin juyayi na tsakiya kaɗan ne, wani sabon ƙarni na magungunan antiallergic zabi.Olopatadine mai ƙarfi ne, mai zaɓaɓɓen antagonist na mai karɓar H1 histamine (Ki = 16-41.1 nM), tare da ƙananan alaƙa ga masu karɓar H2 da H3 (Ki = 43.4 da 172 μM, bi da bi).Yana toshe histamine-induced phosphoinotide juya a cikin keɓaɓɓen sel (IC50 = 9.5-39.9 nM) da kuma hana m cutaneous anaphylaxis a cikin berayen (ED50 = 49 μg / kg) da anaphylactic bronchoconstriction a Guinea aladu (ID50 = 30 ).Olopatadine yana da tasiri wajen magance rashin lafiyar rhinitis da conjunctivitis.Yana kuma danne ƙaiƙayi a cikin marasa lafiya da ke fama da urticaria na yau da kullun.A cikin mutane, wannan maganin antihistamine baya haifar da fahimi ko nakasa psychomotor a allurai na warkewa.
