Palonosetron Hydrochloride CAS 135729-62-3 Tsarkake>99.0% (HPLC) (T) Kamfanin API
Samar da Kasuwancin Palonosetron Hydrochloride da Matsakaici masu alaƙa:
(S) -1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS: 85977-52-2
(R) -1,2,3,4-Tetrahedro-1-Naphthoic Acid CAS: 23357-47-3
(S)-3-Aminoquinuclidine Dihydrochloride CAS: 119904-90-4
3-Quinuclidinone Hydrochloride CAS: 1193-65-3
1-Naphthoic Acid CAS: 86-55-5
Palonosetron Hydrochloride CAS: 135729-62-3 API
Sunan Sinadari | Palonosetron Hydrochloride |
Makamantu | Palonosetron HCl;(S, S)-Palonosetron Hydrochloride;RS-25259;RS25259 197;(S)-2-((S)-Quinuclidin-3-yl) -2,3,3a,4,5,6-Hexahydro-1H-Benzo[de] isoquinolin-1-daya Hydrochloride;(3aS)-2-(3S)-1-Azabicyclo[2.2.2] oct-3-yl-2,3,3a,4,5,6-Hexahydro-1H-benz[de] isoquinolin-1-daya Hydrochloride ;Aloxi;Onicit |
Lambar CAS | 135729-62-3 |
Lambar CAT | RF-API03 |
Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
Tsarin kwayoyin halitta | Saukewa: C19H24N2O |
Nauyin Kwayoyin Halitta | 332.87 |
Sharadi don Gujewa | Zafi Sensitive |
Matsayin narkewa | 307 ℃ (Dec.) |
Solubility a cikin Ruwa | Cikakkiyar Narke Cikin Ruwa |
Solubility | Soluble sosai a cikin Ethanol |
Zazzabi na jigilar kaya | Yanayin yanayi |
COA & MSDS | Akwai |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Fari ko Kashe-White Crystalline Foda |
Palonosetron Hydrochloride | > 99.0% (HPLC) (T) |
Takamaiman Juyawa [α] 20/D | -98.0°~-104.0° |
Ganewa | Ƙara BiI7K4, Ƙirƙirar Ruwan Ruwa na Orange |
Ganewa | TLC Daidaita da Abubuwan Magana |
Ganewa | IR daidai da Standard IR |
Ganewa | Gane a matsayin Chloride |
Solubility | Soluble a cikin ruwa da yardar rai, mai saurin narkewa a cikin methanol, mai narkewa sosai cikin ethanol, mai narkewa cikin acetone. |
Bayyanawa da Launin Magani | Max.Yellow No. 2 Daidaitaccen Magani Launi |
pH wuta | 4.5 ~ 6.5 (10mg/ml) |
Abubuwan da ke da alaƙa | |
Abubuwan da ke da alaƙa A (NO) | <0.10% |
Abubuwan da ke da alaƙa B (Ene-NO) | <0.10% |
Abubuwan da ke da alaƙa C (S,R) | <0.10% |
Abubuwan da ke da alaƙa D (R,S) | <0.50% |
Palonosetron Enantiomer | <0.10% |
Abubuwan da ke da alaƙa E (3-Ene) | <0.50% |
Rashin Tsabtace Guda Daya | <0.10% |
Ragowar Magani | |
Ethanol | <3000ppm |
Tetrahydrofuran | <5000ppm |
DMF | <880ppm |
Hexane na al'ada | <290ppm |
Methyl Alcohol | <3000ppm |
isopropanol | <5000ppm |
Methylbenzene | <890ppm |
Ruwa | <0.30% |
Ragowa akan Ignition | <0.20% |
Asara akan bushewa | <1.00% |
Karfe masu nauyi | <10ppm |
Matsayin Gwaji | Amurka Pharmacopoeia (USP);Turai Pharmacopoeia (EP) |
Amfani | Palonosetron Hydrochloride API;5-HT3 mai adawa;CINV |
Kunshin: kwalban, Kwali Drum, 25kg/Drum, ko bisa ga abokin ciniki ta bukata.
Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.
Palonosetron Hydrochloride (CAS: 135729-62-3) magani ne don hana tashin zuciya da amai, wanda shine sabon nau'in zaɓaɓɓen zaɓi, babban abokin adawar 5-HT3 mai karɓar mai karɓa wanda zai iya toshe amai reflex cibiyar na gefe neurons presynaptic 5-HT.Jin daɗin karɓar karɓar kai tsaye yana rinjayar tsarin kulawa na tsakiya a cikin 5-HT.Jin daɗin mai karɓa na ƙwanƙwasa wanda aka haifar ta hanyar rawar jijiyar vagal afferent bayan yanki, toshe ƙarshen jijiyar ƙwayar cuta a cikin gut, hana sigina zuwa 5-HT.Yanki mai karɓa na iya rage yawan tashin zuciya da amai.Asibiti na tsakiya don kula da m m Emetogenic chemotherapy jawo jinkirin tashin zuciya da amai.Saboda babban tasirin warkarwa, ƙananan sakamako na gefe, tsawon rabin rayuwa (kimanin sa'o'i 40), ƙananan sashi, da sauransu, ya jawo hankali sosai.
Tare da 1,2,3,4-Tetrahydro-1-Naphthoic Acid a matsayin kayan farawa, tsaga, amination, raguwa, cyclization, gishiri na palonosetron hydrochloride granisetron.Nazarin asibiti ya nuna cewa ana iya amfani da palonosetron lafiya tare da corticosteroids, analgesics, antiemetics, antispasmodics da anticholinergic kwayoyi kamar yadda farkon abu, da tsaga, amination, raguwa, cyclization, gishiri palonosetron hydrochloride granisetron.