Palonosetron Hydrochloride CAS 135729-62-3 Tsarkake>99.0% (HPLC) (T) Kamfanin API

Takaitaccen Bayani:

Sunan Chemical: Palonosetron Hydrochloride

Saukewa: 135729-62

Bayyanar: Fari ko Kashe-White Crystalline Foda

Tsafta:> 99.0% (HPLC) (T)

Palonosetron Hydrochloride mai ƙarfi ne mai ƙarfi, zaɓaɓɓe kuma mai aiki da baki antagonist mai karɓa na 5-HT3 da aka yi amfani da shi wajen rigakafi da jiyya na tashin zuciya da amai (CINV).Antiemetic.

Tuntuɓi: Dr. Alvin Huang

Wayar hannu/Wechat/WhatsApp: +86-15026746401

Inquiry: alvin@ruifuchem.com


Cikakken Bayani

Samfura masu dangantaka

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Bayani:

Abubuwan Sinadarai:

Sunan Sinadari Palonosetron Hydrochloride
Makamantu Palonosetron HCl;(S, S)-Palonosetron Hydrochloride;RS-25259;RS25259 197;(S)-2-((S)-Quinuclidin-3-yl) -2,3,3a,4,5,6-Hexahydro-1H-Benzo[de] isoquinolin-1-daya Hydrochloride;(3aS)-2-(3S)-1-Azabicyclo[2.2.2] oct-3-yl-2,3,3a,4,5,6-Hexahydro-1H-benz[de] isoquinolin-1-daya Hydrochloride ;Aloxi;Onicit
Lambar CAS 135729-62-3
Lambar CAT RF-API03
Matsayin Hannun jari A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton
Tsarin kwayoyin halitta Saukewa: C19H24N2O
Nauyin Kwayoyin Halitta 332.87
Sharadi don Gujewa Zafi Sensitive
Matsayin narkewa 307 ℃ (Dec.)
Solubility a cikin Ruwa Cikakkiyar Narke Cikin Ruwa
Solubility Soluble sosai a cikin Ethanol
Zazzabi na jigilar kaya Yanayin yanayi
COA & MSDS Akwai
Alamar Ruifu Chemical

Ƙayyadaddun bayanai:

Abu Ƙayyadaddun bayanai
Bayyanar Fari ko Kashe-White Crystalline Foda
Palonosetron Hydrochloride > 99.0% (HPLC) (T)
Takamaiman Juyawa [α] 20/D -98.0°~-104.0°
Ganewa Ƙara BiI7K4, Ƙirƙirar Ruwan Ruwa na Orange
Ganewa TLC Daidaita da Abubuwan Magana
Ganewa IR daidai da Standard IR
Ganewa Gane a matsayin Chloride
Solubility Soluble a cikin ruwa da yardar rai, mai saurin narkewa a cikin methanol, mai narkewa sosai cikin ethanol, mai narkewa cikin acetone.
Bayyanawa da Launin Magani Max.Yellow No. 2 Daidaitaccen Magani Launi
pH wuta 4.5 ~ 6.5 (10mg/ml)
Abubuwan da ke da alaƙa
Abubuwan da ke da alaƙa A (NO) <0.10%
Abubuwan da ke da alaƙa B (Ene-NO) <0.10%
Abubuwan da ke da alaƙa C (S,R) <0.10%
Abubuwan da ke da alaƙa D (R,S) <0.50%
Palonosetron Enantiomer <0.10%
Abubuwan da ke da alaƙa E (3-Ene) <0.50%
Rashin Tsabtace Guda Daya <0.10%
Ragowar Magani
Ethanol <3000ppm
Tetrahydrofuran <5000ppm
DMF <880ppm
Hexane na al'ada <290ppm
Methyl Alcohol <3000ppm
isopropanol <5000ppm
Methylbenzene <890ppm
Ruwa <0.30%
Ragowa akan Ignition <0.20%
Asara akan bushewa <1.00%
Karfe masu nauyi <10ppm
Matsayin Gwaji Amurka Pharmacopoeia (USP);Turai Pharmacopoeia (EP)
Amfani Palonosetron Hydrochloride API;5-HT3 mai adawa;CINV

Kunshin & Ajiya:

Kunshin: kwalban, Kwali Drum, 25kg/Drum, ko bisa ga abokin ciniki ta bukata.

Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.

Amfani:

1

FAQ:

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Aikace-aikace:

Palonosetron Hydrochloride (CAS: 135729-62-3) magani ne don hana tashin zuciya da amai, wanda shine sabon nau'in zaɓaɓɓen zaɓi, babban abokin adawar 5-HT3 mai karɓar mai karɓa wanda zai iya toshe amai reflex cibiyar na gefe neurons presynaptic 5-HT.Jin daɗin karɓar karɓar kai tsaye yana rinjayar tsarin kulawa na tsakiya a cikin 5-HT.Jin daɗin mai karɓa na ƙwanƙwasa wanda aka haifar ta hanyar rawar jijiyar vagal afferent bayan yanki, toshe ƙarshen jijiyar ƙwayar cuta a cikin gut, hana sigina zuwa 5-HT.Yanki mai karɓa na iya rage yawan tashin zuciya da amai.Asibiti na tsakiya don kula da m m Emetogenic chemotherapy jawo jinkirin tashin zuciya da amai.Saboda babban tasirin warkarwa, ƙananan sakamako na gefe, tsawon rabin rayuwa (kimanin sa'o'i 40), ƙananan sashi, da sauransu, ya jawo hankali sosai.

Tare da 1,2,3,4-Tetrahydro-1-Naphthoic Acid a matsayin kayan farawa, tsaga, amination, raguwa, cyclization, gishiri na palonosetron hydrochloride granisetron.Nazarin asibiti ya nuna cewa ana iya amfani da palonosetron lafiya tare da corticosteroids, analgesics, antiemetics, antispasmodics da anticholinergic kwayoyi kamar yadda farkon abu, da tsaga, amination, raguwa, cyclization, gishiri palonosetron hydrochloride granisetron.

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