Pazopanib Hydrochloride CAS 635702-64-6 Tsarkake> 99.0% (HPLC) API Factory Factory Hoton

Pazopanib Hydrochloride CAS 635702-64-6 Tsarkake>99.0% (HPLC) Kamfanin API

Takaitaccen Bayani:

Sunan Chemical: Pazopanib Hydrochloride

Saukewa: 635702-64

Bayyanar: Fari zuwa Foda Rawaya kaɗan

Tsafta:> 99.0% (HPLC)

Tyrosine kinase receptor inhibitor don maganin ci-gaban ciwon daji na koda ko sarcoma mai laushi mai laushi

API High Quality, Kasuwancin Kasuwanci

Inquiry: alvin@ruifuchem.com

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Bayani:

Samar da Mai ƙira tare da Tsaftataccen Tsafta da Tsayayyen inganci
Sunan Chemical: Pazopanib Hydrochloride
Saukewa: 635702-64
Tyrosine kinase receptor inhibitor don maganin ci-gaban ciwon daji na renal ko sarcoma mai laushi mai laushi waɗanda suka sami kafin chemotherapy.
API High Quality, Kasuwancin Kasuwanci

Abubuwan Sinadarai:

Sunan Sinadari	Pazopanib Hydrochloride
Makamantu	Pazopanib HCl;GW786034 HCL;Votrient;5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide Hydrochloride
Lambar CAS	635702-64-6
Lambar CAT	RF-API93
Matsayin Hannun jari	A Hannun jari, Ma'aunin Samfuran Har zuwa Daruruwan Kilogram
Tsarin kwayoyin halitta	Saukewa: C21H23N7O2S.ClH
Nauyin Kwayoyin Halitta	473.987
Solubility	DMSO
Matsayin narkewa	300.0 ~ 304.0 ℃
Alamar	Ruifu Chemical

Ƙayyadaddun bayanai:

Abu	Ƙayyadaddun bayanai
Bayyanar	Fari zuwa Foda Jawo Kadan
Ganewa	Bakan sharar infraed na samfurin gwajin ya yi daidai da na ma'auni
Ragowa akan Ignition	≤0.50%
Duk wani Rashin Tsabtace Mutum	≤0.30%
Jimlar ƙazanta	≤1.50%
Karfe masu nauyi	≤10ppm
Tsarkake / Hanyar Bincike	≥99.0% (HPLC)
Matsayin Gwaji	Matsayin Kasuwanci
Amfani	API, Tyrosine kinase receptor inhibitor

Kunshin & Ajiya:

Kunshin: Bottle, Aluminum tsare jakar, Kwali drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.

Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.

Amfani:

FAQ:

Aikace-aikace:

Pazopanib Hydrochloride (CAS 635702-64-6) shine mai hanawa mai yawa-tyrosine kinase mai karɓar haɓakar haɓakar haɓakar haɓakar ƙwayar cuta (VEGFR) -1, VEGFR-2, VEGFR-3, mai karɓar haɓakar haɓakar platelet (PDGFR) -a da - β, fibroblast girma factor receptor (FGFR) -1 da -3, cytokine receptor (Kit), interleukin-2 receptor-inducible T-cell kinase (Itk), lymphocyte-specific protein tyrosine kinase (Lck), da transmembrane glycoprotein tyrosine. kinase (cFms).A cikin vitro, pazopanib ya hana autophosphorylation na ligand na VEGFR-2, Kit, da PDGFR-beta masu karɓa.A cikin vivo, pazopanib ya hana VEGF-induced VEGFR-2 phosphorylation a cikin huhu na linzamin kwamfuta, angiogenesis a cikin ƙirar linzamin kwamfuta, da kuma ci gaban wasu ƙwayoyin ƙwayar cuta na ɗan adam xenografts a cikin mice.Cibiyar Abinci da Magunguna ta Amurka ta amince da ita don cutar sankara ta koda a cikin 2009 kuma ana sayar da ita a ƙarƙashin sunan kasuwanci na Votrient ta masana'antar maganin, GlaxoSmithKline.Votrient shine mai hana kinase wanda aka nuna don kula da marasa lafiya tare da: 1) ciwon daji na renal cell.2) ci-gaba sarcoma taushi nama wadanda suka samu kafin chemotherapy.