Pirfenidone CAS 53179-13-8 Tsafta ≥99.0% IPF
Ƙarfafawa Tare da Babban Tsafta, Samar da Kasuwanci
Sunan Chemical: Pirfenidone
Saukewa: 53179-13-8
Sunan Sinadari | Pirfenidone |
Makamantu | Perfenidone;5-Methyl-1-Phenylpyridine-2(1H) -daya;PFD;S-7701;AMR-69 |
Lambar CAS | 53179-13-8 |
Lambar CAT | RF-API108 |
Matsayin Hannun jari | A Stock |
Tsarin kwayoyin halitta | Saukewa: C12H11 |
Nauyin Kwayoyin Halitta | 185.22 |
Matsayin narkewa | 96.0 zuwa 97.0 ℃ |
Solubility | Mai narkewa a cikin DMSO |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Fari zuwa Haske Rawaya Crystalline Foda |
Ganewa | IR |
Tsafta | ≥99.0% |
Asara akan bushewa | ≤0.50% |
Sulfated ash | ≤0.20% |
Rashin Tsabtace Guda Daya | ≤0.50% |
Jimlar ƙazanta | ≤1.0% |
Karfe masu nauyi | ≤20ppm |
Matsayin Gwaji | Matsayin Kasuwanci |
Amfani | API, Idiopathic Fibrosis Pulmonary (IPF) |
Kunshin: Bottle, Aluminum tsare jakar, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi.
Pirfenidone (CAS: 53179-13-8) yana cikin rukunin magunguna da ake kira magungunan antifibrotic.Pirfenidone ya nuna aiki a cikin yanayin fibrotic da yawa, ciki har da na huhu, koda da hanta.Yana shafar tsarin garkuwar jikin ku kuma yana rage adadin fibrosis (tabo) a cikin huhu.Pirfenidone yana ɗaya daga cikin magunguna biyu da aka yarda a Kanada don magance Fibrosis na Pulmonary Idiopathic (IPF).Pirfenidone shine mai hanawa don samar da TGF-β da kuma TGF-β yana haɓaka samar da collagen, yana rage samar da TNF-α da IL-1β, kuma yana da anti-fibrotic da anti-inflammatory Properties.An fara yarda da shi a Japan don maganin marasa lafiya tare da fibrosis na huhu na huhu bayan gwaje-gwaje na asibiti, a ƙarƙashin sunan kasuwanci na Pirespa ta Shionogi, a cikin 2008. An amince da shi don amfani a cikin Tarayyar Turai a 2011, a Kanada a 2012, kuma a cikin Amurka a watan Oktoba 2014.