Posaconazole CAS 171228-49-2 API Factory Triazole Wakilin Antifungal Babban inganci

Takaitaccen Bayani:

Suna: Posaconazole

Saukewa: 171228-49-2

Fari zuwa Kashe-White Crystalline Foda

Matsayi: 98.0% ~ 102.0%

Posaconazole shine Triazole Antifungal Agent

API High Quality, Kasuwancin Kasuwanci

Tuntuɓi: Dr. Alvin Huang

Wayar hannu/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com  


Cikakken Bayani

Samfura masu dangantaka

Tags samfurin

Bayani:

Abubuwan Sinadarai:

Sunan Sinadari Posaconazole
Makamantu POS;SCH 56592;4-[4-[4-[4-[[(3R,5R) -5- (2,4-Difluorophenyl) -5- (1,2,4-triazol-1-ylmethyl) oxolan-3-yl] methoxy]phenyl] piperazin-1-yl] phenyl] -2-[(2S,3S) -2-hydroxypentan-3-yl] -1,2,4-triazol-3-daya
Lambar CAS 171228-49-2
Lambar CAT RF-API77
Matsayin Hannun jari A Hannun jari, Ma'aunin Samfuran Har zuwa Daruruwan Kilogram
Tsarin kwayoyin halitta Saukewa: C37H42F2N8O4
Nauyin Kwayoyin Halitta 700.78
Yawan yawa 1.36 g/cm 3
Solubility Mai narkewa a cikin DMSO, Mai narkewa cikin Ruwa
Yanayin jigilar kaya An aika Karkashin Zazzabin yanayi
Alamar Ruifu Chemical

Ƙayyadaddun bayanai:

Abu Ƙayyadaddun bayanai
Bayyanar Fari zuwa Kashe-White Crystalline Foda
Identification A IR: Bakan samfurin infrared ya kamata ya yi daidai da na abin da ake tunani
Identity B Lokacin riƙe HPLC kama da abin tunani
Matsayin narkewa 167.0 ~ 171.0 ℃
Takamaiman Juyawa [a]20 -24.0° ~ -28.0° (C=1, CHCL3)
Ruwa (KF) ≤1.0%
Ragowa akan Ignition ≤0.10%
Abubuwa masu alaƙa
HT 909-24 ≤0.20%
Duk wani Rashin Tsabtace Mutum ≤0.10%
Jimlar ƙazanta ≤1.0%
Ragowar Magani
Methanol ≤3000ppm
Methyl tert-Butyl Ether ≤5000ppm
isopropanol ≤5000ppm
Dimethyl sulfoxide ≤5000ppm
Dichloromethane ≤600ppm
Assay 98.0% ~ 102.0% (Lissafi akan busasshiyar tushe)
Karfe masu nauyi ≤10ppm
Isomer Enantiomer ≤0.10%
Kowane Mutum Najasa ≤0.10%
Jimlar ƙazanta ≤1.0%
Matsayin Gwaji Matsayin Kasuwanci;USP;BP;EP Standard
Amfani API, Triazole Antifungal Agent

Kunshin & Ajiya:

Kunshin: Bottle, Aluminum tsare jakar, Kwali drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.

Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.

Amfani:

1

FAQ:

Aikace-aikace:

Posaconazole (CAS 171228-49-2), babban bakan ne, tsara na biyu, triazole fili tare da aikin antifungal, wanda aka ƙaddamar a cikin Burtaniya, shine sabon memba na rukunin azole na maganin rigakafi don isa kasuwa.Ana nuna shi don jiyya da rigakafi na kewayon cututtukan cututtukan fungal masu haɗari, gami da aspergillosis, fusariosis, chromoblastomycosis, mycetoma, da coccidiomycosis a cikin marasa lafiya waɗanda ba su da ƙarfi, ko rashin haƙuri, daidaitaccen jiyya tare da amphotericin B da / ko itraconazole.A cikin Amurka, an yarda da rigakafin cututtukan Aspergillus da Candida masu kamuwa da cuta a cikin marasa lafiya masu shekaru 13 waɗanda ke cikin haɗarin haɓaka waɗannan cututtukan saboda ƙarancin rigakafi.Bugu da ƙari, an yarda da shi don maganin oropharyngeal candidiasis.Posaconazole yana da faɗaɗa aikin bakan na sauran mambobi na azole antifungals.Baya ga m aiki a kan refractory lokuta na aspergillosis da fluconazole-resistant Candida, yana nuna aiki a kan Zygomycetes.Posaconazole magani ne na maganin fungal na triazole wanda aka sayar a Amurka ta Schering-Plough a ƙarƙashin sunan kasuwanci Noxafil.

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