Pregabalin CAS 148553-50-8 Tsarkake>99.0% (HPLC) API ɗin Antiepileptic
Mai ƙera tare da Babban Tsafta da Samar da Kasuwanci
Sunan Chemical: PregabalinSaukewa: 148553-50-8
Pregabalin maganin rigakafi ne na ƙarni na biyu (AED)
Sunan Sinadari | Pregabalin |
Makamantu | (S) -3- (Aminomethyl) -5-Methylhexanoic Acid;PD-144723;PD144723;CI 1008;CI-1008;Lyrica |
Lambar CAS | 148553-50-8 |
Lambar CAT | RF-API57 |
Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
Tsarin kwayoyin halitta | Saukewa: C8H17NO2 |
Nauyin Kwayoyin Halitta | 159.23 |
Matsayin narkewa | 194.0 ~ 196.0 ℃ |
Solubility a cikin Ruwa | A zahiri Mara narkewa a cikin Ruwa |
Solubility | Soluble sosai a cikin Ethanol |
Yanayin jigilar kaya | Karkashin Zazzabi |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Fari zuwa Kashe-White Crystalline Foda |
Ganewa | IR: Mai kama da Abun Magana |
Takamaiman Juyawa | +10.0°~+13.0° (C=1, Ruwa) |
Asara akan bushewa | <0.50% |
Sulfate ash | <0.10% |
Abubuwa masu alaƙa | Najasa A <0.15% |
Abubuwan da Ba a Fahimce su ba suna Haɓakawa Kafin Pregabalin (gwajin A) <0.10% | |
Abubuwan da Ba A Fahimci Ba A Fahimci Ba Bayan Pregabalin (gwajin B) <0.10% | |
Jimlar gwajin A da B <0.50% | |
Tsaftace Ta HPLC R-Isomer | <0.15% |
Karfe masu nauyi (kamar Pb) | <10ppm |
Chlorides (Cl) | <0.05% |
Ragowar Magani | |
Isopropyl Alcohol | <5000ppm |
Ethyl acetate | <5000ppm |
Tetrahydrofuran | <250ppm |
Isopropyl Ether | <500ppm |
Ethanol | <1000ppm |
Tsarkake / Hanyar Bincike | > 99.0% (HPLC akan busasshiyar tushe) |
Matsayin Gwaji | Matsayin Kasuwanci |
Amfani | Magungunan Antiepileptic API |
Kunshin: Bottle, Aluminum tsare jakar, 25kg / kwali Drum, ko bisa ga abokin ciniki ta bukata
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske & danshi
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Pregabalin magani ne na ƙarni na biyu (AED) wanda aka sani da sunan mallakar mallakar Lyrica (Pfizer, Tadworth) a cikin Burtaniya da Amurka, yana da tsarin γ-amino butyric acid akan tsarin sa na ƙwayoyin cuta, wanda ke da tasirin anticonvulsant, kuma shine. nasarar haɓakawa da kamfanin Pfizer ya yi don maganin ciwon neuropathic na gefe, ko jiyya na ɓangaren ɓarna.Pregabalin magani ne na Anticonvulsant da antiepileptic da ake amfani da shi don magance farfaɗiya, ciwon neuropathic, fibromyalgia, da rikicewar tashin hankali gabaɗaya.Amfani da shi don farfaɗo shine azaman ƙarin jiyya don ɓarna na ɓarna tare da ko ba tare da gamawa na biyu a cikin manya ba.A cikin Disamba 2008, Cibiyar Abinci da Magunguna ta Amurka (FDA) ta amince da pregabalin (sunan ciniki "Lyrica") don maganin ciwon ciwon neuropathic na ciwon sukari (DPN) da neuralgia na baya-bayan nan (PHN) waɗanda duka biyun ciwon neuropathic na yau da kullun.Pregabalin yana da alamar da aka yarda kuma ana amfani dashi sosai don maganin rashin lafiyar gaba ɗaya.Yawancin bazuwar, makafi biyu, gwaje-gwaje masu sarrafa placebo sun gano cewa pregabalin magani ne mai inganci ga marasa lafiya da ke da rikicewar tashin hankali da rikice-rikicen zamantakewa.Matsakaicin adadin maganin farfaɗo-daidaitacce: 25 MG bd na kwanaki 7, za a ƙara shi da 50 MG kowane 7days;gyare-gyare na yau da kullum 300 MG kowace rana, zuwa kashi 2 ko 3 (max. 600 MG kowace rana, zuwa kashi 2 ko 3).Rashin damuwa na gabaɗaya: 150 MG kowace rana, raba zuwa kashi 2 ko 3, na kwanaki 7, don haɓaka ta 150 MG kowace rana 7 (max. 600 MG kowace rana, raba zuwa kashi 2 ko 3).Idan dakatar da pregabalin, ana ba da shawarar a matsa sama da akalla mako 1 don guje wa janyewar ba zato ba tsammani.Gargaɗi Marasa lafiya da yanayin da zai iya haifar da encephalopathy.Marasa lafiya tare da gazawar zuciya mai tsanani.
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