Pyridine-3-Sulfonyl Chloride CAS 16133-25-8 Tsabtace
Bayar da Vonoprazan Fumarate da Matsakaicin Mahimmanci
5- (2-Fluorophenyl) pyrrole-3-Carboxaldehyde CAS 881674-56-2
Pyridine-3-Sulfonyl Chloride CAS 16133-25-8
Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2
| Sunan Sinadari | Pyridine-3-sulfonyl chloride |
| Makamantu | 3-Pyridinesulfonyl Chloride;3-Pyridylsulfonyl Chloride;m-Pyridinesulfonyl chloride;Piperidine-3-sulfonylchloride |
| Lambar CAS | 16133-25-8 |
| Lambar CAT | Saukewa: RF-PI540 |
| Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
| Tsarin kwayoyin halitta | Saukewa: C5H4ClNO2S |
| Nauyin Kwayoyin Halitta | 177.61 |
| Alamar | Ruifu Chemical |
| Abu | Ƙayyadaddun bayanai |
| Bayyanar | Ruwa mara launi ko Kodadden Ruwa |
| Tsarkake / Hanyar Bincike | ≥98.5% (GC) |
| Wurin Tafasa | 110.0 ~ 112.0 ℃/2mm Hg |
| Rashin Tsabtace Guda Daya | ≤0.50% |
| Jimlar ƙazanta | ≤1.5% |
| Matsayin Gwaji | Matsayin Kasuwanci |
| Amfani | Matsakaicin Vonoprazan Fumarate (CAS: 1260141-27-2) |
Kunshin: Kwalba, 25kg / Ganga, ko bisa ga bukatun abokin ciniki.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi.
Pyridine-3-Sulfonyl Chloride (CAS: 16133-25-8) matsakaici ne na Vonoprazan Fumarate (CAS: 1260141-27-2).Vonoprazan Fumarate, wanda Takeda da Otsuka suka gano kuma suka haɓaka, PMDA na Japan ya amince da shi a cikin Disamba 2014, kuma ana nuna shi don maganin cututtukan ciki, ulcer na duodenal da reflux esophagitis.Vonoprazan fumarate yana da sabon tsarin aikin da ake kira potassium-competitive acid blockers, wanda ke hana daurin potassium ions zuwa H+, K+-ATPase (wanda aka fi sani da famfo proton) a matakin karshe na fitar da acid na ciki a cikin sel parietal na ciki.Vonoprazan baya hana ayyukan Na +, K+-ATPase ko da a lokuta 500 mafi girma fiye da na ƙimar su IC50 akan aikin H+, K+-ATPase na ciki.Bugu da ƙari kuma, miyagun ƙwayoyi ba shi da tasiri ta hanyar asiri na ciki, sabanin PPIs.
