Ramelteon Matsakaici 12 CAS 1053239-39-6 Tsafta > 98.0% (HPLC)

Takaitaccen Bayani:

Sunan Chemical: 2- (2,6,7,8-Tetrahydro-1H-Indeno [5,4-b]furan-8-yl)ethanamine Hydrochloride

Synonyms: Ramelteon Intermediate 12

Saukewa: 1053239-39-6

Tsafta:> 98.0% (HPLC)

Bayyanar: Fari zuwa Kashe-Farin Ƙaƙƙarfan Foda

Matsakaicin Ramelteon (CAS: 196597-26-9)

Tuntuɓi: Dr. Alvin Huang

Wayar hannu/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Cikakken Bayani

Samfura masu dangantaka

Tags samfurin

Bayani:

Abubuwan Sinadarai:

Sunan Sinadari 2- (2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl) ethanamine Hydrochloride
Makamantu Ramelteon Matsakaici 12;Ramelteon Stage-2 Rashin Tsabta;1,6,7,8-Tetrahydro-2H-Indeno[5,4-B] Furan-8-Ethanamine Hydrochloride
Lambar CAS 1053239-39-6
Lambar CAT Saukewa: RF2887
Matsayin Hannun jari A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton
Tsarin kwayoyin halitta Saukewa: C13H18ClNO
Nauyin Kwayoyin Halitta 239.74
Matsayin narkewa 165.0 ~ 167.0 ℃
Yawan yawa 1.058± 0.06 g/cm3
Alamar Ruifu Chemical

Ƙayyadaddun bayanai:

Abu Ƙayyadaddun bayanai
Bayyanar Fari zuwa Kashe-Farin Tsayayyen Foda
Tsarkake / Hanyar Bincike 98.0% (HPLC)
Asara akan bushewa <1.00%
Tsaftace Guda Daya <1.00%
Jimlar ƙazanta <2.00%
1 H NMR Spectrum Daidaita Da Tsarin
Matsayin Gwaji Matsayin Kasuwanci
Amfani Matsakaicin Ramelteon (CAS: 196597-26-9)

Kunshin & Ajiya:

Kunshin: Bottle, Aluminum tsare jakar, 25kg / kwali Drum, ko bisa ga abokin ciniki ta bukata

Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi

Amfani:

Isasshen Ƙarfin: isassun wurare da masu fasaha

Sabis na Ƙwararru: Sabis na siyan tasha ɗaya

Kunshin OEM: Kunshin al'ada da alamar akwai

Bayarwa da sauri: Idan yana cikin haja, garantin isar da kwanaki uku

Ƙarfin Ƙarfi: Kula da haja mai ma'ana

Taimakon Fasaha: Akwai maganin fasaha

Sabis na Haɗa na Musamman: Ya bambanta daga gram zuwa kilos

High Quality: An kafa cikakken tsarin tabbatar da inganci

FAQ:

Yadda ake siya?Da fatan za a tuntuɓiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

Kwarewar Shekaru 15?Muna da fiye da shekaru 15 na gwaninta a cikin ƙira da fitarwa na matsakaicin matsakaicin magunguna masu inganci ko sinadarai masu kyau.

Manyan Kasuwanni?Sayarwa zuwa kasuwannin cikin gida, Arewacin Amurka, Turai, Indiya, Koriya, Jafananci, Australia, da sauransu.

Fa'idodi?Babban inganci, farashi mai araha, sabis na ƙwararru da tallafin fasaha, bayarwa da sauri.

inganciTabbaci?Tsananin kula da ingancin inganci.Kayan aikin ƙwararru don bincike sun haɗa da NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, gwajin ƙayyadaddun ƙwayoyin cuta, da sauransu.

Misali?Yawancin samfurori suna ba da samfurori kyauta don ƙima mai kyau, farashin jigilar kaya ya kamata a biya ta abokan ciniki.

Binciken Masana'antu?Ma'aikata duba maraba.Da fatan za a yi alƙawari a gaba.

MOQ?Babu MOQ.Karamin tsari abin karɓa ne.

Lokacin Bayarwa? Idan cikin hannun jari, garantin isar da kwana uku.

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Tsarin al'ada?Zai iya ba da sabis na haɗawa na al'ada don dacewa da buƙatun bincikenku.

Sharuɗɗan Biyan kuɗi?Za a fara aiko da daftari na Proforma bayan tabbatar da oda, an rufe bayanan bankin mu.Biya ta T/T (Telex Transfer), PayPal, Western Union, da dai sauransu.

Aikace-aikace:

2- (2,6,7,8-Tetrahydro-1H-Indeno [5,4-b]furan-8-yl) ethanamine Hydrochloride (CAS: 1053239-39-6) shine matsakaicin Ramelteon (CAS: 196597- 26-9).Ba kamar yawancin jiyya na rashin barci ba waɗanda ke kaiwa ga hadaddun masu karɓa na GABA (g-aminobutyric acid), Ramelteon agonist ne na mai karɓar melatonin.Musamman ma, yana da babban zaɓi don ƙananan nau'ikan MT1 da MT2, waɗanda aka sanya su a cikin kiyaye rhythms na circadian, akan mai karɓar MT3 da ke da alhakin sauran ayyukan melatonin.Rashin kusancinsa don ba kawai hadaddun mai karɓar GABA ba har ma neurotransmitter, dopaminerigic, opiate, da masu karɓar benzodiazepine suna ba da shawarar ingantaccen bayanin martaba ba tare da yuwuwar cin zarafi na magungunan hypnotic waɗanda ke kaiwa ga waɗannan masu karɓa ba.Don haka, Ramelteon ba magani ne da aka tsara ba.Metabolites na farko sun haɗa da hydroxylation da oxidation zuwa nau'in carbonyl tare da metabolites na biyu sakamakon glucuronidation.Tun da CYP1A2 shine babban isozyme da ke cikin hanta metabolism na Ramelteon, bai kamata a sha shi tare da masu hana CYP1A2 masu ƙarfi ba, kamar fluvoxamine.Gudanar da haɗin gwiwa tare da ko dai ketoconazole (mai hana CYP3A4) ko fluconazole (mai hana CYP2C9 mai ƙarfi) ya haifar da ƙaruwa mai yawa a cikin AUC da Cmax, amma haɓakar haɓakawa da haɓakar ƙwayar plasma mai girma na Ramelteon ya hana buƙatar gyaran kashi.Sashin kunshin, duk da haka, yana gargaɗin marasa lafiya game da haɗin gwiwa tare da masu hana CYP3A4 masu ƙarfi da CYP2C9.Dangane da sakamakon gwajin asibiti, shawarar da aka ba da shawarar na Ramelteon shine 8mg ana ɗaukar shi a cikin mintuna 30 na zuwa barci.Bugu da ƙari, yin taka tsantsan na haɗin gwiwa tare da masu hana CYP, bai kamata a yi amfani da shi ba a cikin marasa lafiya da ciwon hanta mai tsanani.Abubuwan da ba su da kyau, waɗanda aka lura a cikin 5% na marasa lafiya a cikin nazarin asibiti, sun kasance rashin tausayi, damuwa, tashin zuciya, gajiya, ciwon kai, da rashin barci.

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