Remdesivir GS-5734 CAS 1809249-37-3 COVID-19 API High Quality

Takaitaccen Bayani:

Sunan Chemical: Remdesivir (GS-5734)

Saukewa: 1809249-37-3

Bayyanar: Fari zuwa Kashe-Farin Ƙaƙƙarfan Foda

Matsayi: 98.0% ~ 102.0%

Remdesivir don maganin COVID-19

API High Quality, Kasuwancin Kasuwanci

Inquiry: alvin@ruifuchem.com


Cikakken Bayani

Samfura masu dangantaka

Tags samfurin

Bayani:

Abubuwan Sinadarai:

Sunan Sinadari Remdesivir
Makamantu GS-5734;2-ethylbutyl ((S)-((2R,3S,4R,5R)-5-(4-aminopyrrolo [2,1-f] [1,2,4]triazin-7-yl) -5-cyano -3,4-dihydroxytetrahydrofuran-2-yl) methoxy) (phenoxy) phosphoryl - L-alaninate
Lambar CAS 1809249-37-3
Lambar CAT RF-API96
Matsayin Hannun jari A Hannun jari, Ma'aunin Samfuran Har zuwa Daruruwan Kilogram
Tsarin kwayoyin halitta Saukewa: C27H35N6O8P
Nauyin Kwayoyin Halitta 602.58
Yawan yawa 1.47± 0.1 g/cm3
Alamar Ruifu Chemical

Ƙayyadaddun bayanai:

Abu Ƙayyadaddun bayanai
Bayyanar Fari zuwa Kashe-Farin Tsayayyen Foda
Identification A IR: Bakan samfurin infrared ya kamata ya yi daidai da na abin da ake tunani
Identity B Lokacin riƙe HPLC kama da abin tunani
Takamaiman Juyawa -19.0 ~ -22.0°
Solubility Solule a cikin Methanol, Mai Soluble a cikin Ethanol, Dan Soluble a cikin Acetonitrile, Mai Rashin narkewa cikin Ruwa
Abubuwa masu alaƙa
Duk wani Rashin Tsabtace Mutum ≤0.10%
Jimlar ƙazanta ≤1.0%
RD-3.1 ≤0.10%
RD-C ≤0.10%
RD-D ≤0.10%
RD-E ≤0.10%
RP-Isomer ≤0.10%
Nitrophenol ≤0.10%
Ragowar Magani
Methanol Dichloride ≤6000ppm
Acetone ≤5000ppm
Isopropyl Alcohol ≤5000ppm
Acetonitrile ≤410pm
Dichloromethane ≤600ppm
Methyl tert Butyl Ether ≤5000ppm
Ethyl acetate ≤5000ppm
Tetrahydrofuran ≤720ppm
n-Heptane ≤5000ppm
Assay 98.0% ~ 102.0% (Lissafi akan busasshiyar tushe)
Jimlar Ƙididdigar Aerobic
Bacteria Aerobic ≤100cfu/g
Yisti da Mold ≤10cfu/g
E. Kwal Korau
Bacterial Endotoxin ≤1.0EU
Karfe masu nauyi ≤20ppm
Matsayin Gwaji Matsayin Kasuwanci
Amfani API, COVID-19

Kunshin & Ajiya:

Kunshin: Bottle, Aluminum tsare jakar, Kwali drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.

Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.

Amfani:

1

FAQ:

Aikace-aikace:

Remdesivir (CAS 1809249-37-3), wanda aka sayar a ƙarƙashin sunan alamar Veklury, babban maganin rigakafin ƙwayar cuta ne wanda kamfanin biopharmaceutical na Gileyad Sciences ya haɓaka.Ana gudanar da shi ta hanyar allura a cikin jijiya.A lokacin cutar ta COVID-19, an yarda da remdesivir ko izini don amfani da gaggawa don kula da COVID-19 a cikin ƙasashe kusan 50.Sabunta jagororin daga Hukumar Lafiya ta Duniya a cikin Nuwamba 2020 sun haɗa da shawarar sharadi game da amfani da Remdesivir don maganin COVID-19.An samo asali ne na Remdesivir don magance cutar hanta ta C, kuma daga baya aka bincikar cutar ta Ebola da kuma cututtukan ƙwayoyin cuta na Marburg kafin a yi nazari a matsayin maganin cutar bayan kamuwa da cutar COVID-19.Mafi yawan sakamako masu illa a cikin masu sa kai masu lafiya shine haɓaka matakan jini na enzymes hanta (alama ta matsalolin hanta).Mafi yawan illar illa a cikin mutanen da ke da COVID-19 shine tashin zuciya.Abubuwan da ke haifar da lahani na iya haɗawa da kumburin hanta da kuma abin da ke da alaƙa da jiko tare da tashin zuciya, ƙarancin hawan jini, da gumi.Remdesivir prodrug ne wanda aka yi niyya don ba da damar isar da intracellular na GS-441524 monophosphate da biotransformation na gaba zuwa GS-441524 triphosphate, mai hana ribonucleotide analogue mai hanawa na kwayar cutar RNA polymerase.

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