Roflumilast CAS 162401-32-3 Assay 99.0 ~ 101.0% API
Ruifu Chemical Supply Roflumilast Intermediates:
Farashin CAS 162401-32-3
4-Amino-3,5-Dichloropyridine CAS 22889-78-7
Sunan Sinadari | Roflumilast |
Makamantu | 3- (Cyclopropylmethoxy) -N- (3,5-Dichloropyridin-4-yl)-4- (Ddifluoromethoxy) benzamide |
Lambar CAS | 162401-32-3 |
Lambar CAT | Saukewa: RF-PI2075 |
Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
Tsarin kwayoyin halitta | Saukewa: C17H14Cl2F2N2O3 |
Nauyin Kwayoyin Halitta | 403.21 |
Yawan yawa | 1.471± 0.060 g/cm3 |
Hankali | Zafi Sensitive |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Fari ko Kusan Farin Crystalline Foda |
Solubility | Mai soluble kyauta a cikin acetone, dan kadan mai narkewa a cikin acetronitrile, ba zai iya narkewa a cikin ethanol mai anhydrous, a zahiri ba zai iya narkewa cikin ruwa. |
Matsayin narkewa | 157.0 ~ 162.0 ℃ |
Asara akan bushewa | <0.50% |
Ragowa akan Ignition | ≤0.10% |
Karfe masu nauyi | ≤10ppm |
Chloride | ≤0.01% |
Bayanin A. UV | Matsakaicin iyakar sha ya kamata ya kasance a 213 ~ 251nm |
Bayanin B. IR | Samfurin shayarwar IR yayi daidai da na abin da ake magana akai |
Gano C. | Yana nuna halayen fluoride |
Abubuwa masu alaƙa | |
Tsaftace Guda Daya | ≤0.10% |
Jimlar ƙazanta | <0.50% |
Ragowar Magani | |
Tert-Butanol | <0.10% |
Tetrahydrofuran | <0.072% |
Toluene | <0.089% |
N, N-Dimethylformamide | <0.088% |
Assay | 99.0 ~ 101.0% (Lissafi akan Busassun Tushen) |
Matsayin Gwaji | Matsayin Kasuwanci |
Amfani | API;COPD |
Kunshin: Bottle, Aluminum tsare jakar, 25kg / kwali Drum, ko bisa ga abokin ciniki ta bukata
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi
Roflumilast (CAS: 162401-32-3) wani zaɓi ne na phosphodiesterase-4 (PDE-4) mai hanawa da kuma fili na benzamide.Kamfanin Altana na Jamus ne ya haɓaka shi a cikin 1993 kuma shine kawai mai hana PDE-4 na baka da ake amfani da shi don magance cututtukan da ke haifar da numfashi da aka amince da siyarwa.Roflumilast shine nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i) wanda aka yi amfani da shi don magance cututtuka masu tsanani (COPD).Abubuwan da ke da su na musamman na iya taimakawa wajen daidaita COPD: lokacin da aka yi amfani da su tare da bronchodilators don kula da marasa lafiya na COPD mai tsananin gaske, Roflumilast na iya samun fa'idar ƙara rage alamun bayyanar cututtuka da tabarbarewar ƙimar, don haka ya sa ya zama magani na farko wanda ke kaiwa marasa lafiya da ke faruwa a cikin yanayin phenotype-spAecific COPD. da matsananciyar toshewar iska mai alaƙa da tari na yau da kullun da wuce gona da iri.Bayan kasancewa magani ga COPD mai tsanani, Roflumilast kuma ana iya amfani dashi don hanawa da magance cututtuka na numfashi na dabbobi, tari na mucosa mashako, mashako mai asthmatic, da kuma mashako mai tsanani da sacculitis na iska tare da ɓarna na fili na numfashi.