(S) -1-Boc-3-Hydroxypiperidine CAS 143900-44-1 Ibrutinib Tsabtace Tsarkake>99.0% (GC)

Takaitaccen Bayani:

Sunan Sinadari: (S)-1-Boc-3-Hydroxypiperidine

Saukewa: 143900-44-1

Tsaftar Chiral:>99.0% (GC)

Tsaftar Sinadari:>99.0% (GC)

Bayyanar: Farin Foda ko Lu'ulu'u

Matsakaicin Ibrutinib (CAS: 936563-96-1)

Kyakkyawan inganci, Samar da Kasuwanci

E-Mail: alvin@ruifuchem.com


Cikakken Bayani

Samfura masu dangantaka

Tags samfurin

Bayani:

Abubuwan Sinadarai:

Sunan Sinadari (S)-1-Boc-3-Hydroxypiperidine
Makamantu (S)-1- (tert-Butoxycarbonyl) -3-Hydroxypiperidine;(S)-1-Boc-3-Piperidinol
Lambar CAS 143900-44-1
Lambar CAT Saukewa: RF-CC299
Matsayin Hannun jari A Hannun jari, Iyawar Samar da Ton 20/wata
Tsarin kwayoyin halitta Saukewa: C10H19NO3
Nauyin Kwayoyin Halitta 201.27
Matsayin narkewa 52.0 ~ 56.0 ℃
Solubility Mai narkewa a cikin methanol
Takamaiman Juyawa [a] 20/D +9.0°~+11.0° (C=1 a cikin Chloroform)
Alamar Ruifu Chemical

Ƙayyadaddun bayanai:

Abu Ƙayyadaddun bayanai
Bayyanar Farin Foda ko Crystals
Chiral Tsafta > 99.5% (GC)
Tsaftar Sinadari > 99.5% (GC)
Ruwa (KF) ≤0.50%
Methanol (GC) ≤50ppm
Ethanol (GC) ≤50ppm
DCM (GC) ≤500ppm
3-Hydroxypiperidine ≤0.10%
3-Hydroxypyridine ≤0.20%
1-Boc-3-Piperidone ≤0.10%
1-Boc-4-Hydroxypiperidine ≤0.10%
1.96 RRT ≤0.20%
Duk Wani Tsaftar Da Ba A Fayyace Ba ≤0.10%
Matsayin Gwaji Matsayin Kasuwanci
Amfani Matsakaicin Magunguna;Chiral mahadi

Kunshin & Ajiya:

Kunshin: Bottle, Aluminum tsare jakar, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata.

Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi.

Amfani:

1

FAQ:

Aikace-aikace:

(S) -1-Boc-3-Hydroxypiperidine (CAS: 143900-44-1) wani muhimmin tsaka-tsaki na chiral don haɗin Ibrutinib (CAS: 936563-96-1).Ibrutinib wani nau'i ne na mai hana Bruton tyrosine kinase (BTK), ana iya amfani dashi don maganin cutar sankarar lymphocytic na kullum (CLL) da lymphoma na mantle cell (MCL).MCL da CLL na cikin ƙwayoyin lymphoma na B-cell ba Hodgkin ba, wanda ke da wuyar warkewa kuma yana da sauƙin maimaitawa.Maganin rigakafi na gama gari ba shi da niyya, sau da yawa yana faruwa 3 ko 4 munanan halayen.Ibrutinib da B lymphocytes na iya yin niyya tare da BTK wanda ya zama dole don samuwar, bambance-bambance, da watsa bayanai, hana ayyukan BTK ba tare da juyewa ba, kuma yana hana yaduwar ƙwayar ƙwayar cuta da rayuwa yadda ya kamata.Ibrutinib zai iya zama da sauri a sha bayan gudanarwa ta baki, a lokacin 1 ~ 2h ya kai matsakaicin maida hankali na jini, mummunan halayen na ɗaya ko biyu, sabili da haka, Ibrutinib zai zama sabon zaɓi na jiyya na CLL da MCL.

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