Sitagliptin Triazole Hydrochloride CAS 762240-92-6 Tsarkake> 99.0% (HPLC) Babban Inganci
Samar da Sitagliptin Phosphate Monohydrate Matsakaici masu alaƙa:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R) -3-Amino-4- (2,4,5-Trifluoro-Phenyl) -Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Matsakaici CAS 486460-21-3
| Sunan Sinadari | 3- (Trifluoromethyl) -5,6,7,8-tetrahydro-[1,2,4]triazolo [4,3-a] pyrazine Hydrochloride |
| Makamantu | Sitagliptin Triazole Hydrochloride;Sitagliptin Intermediate A |
| Lambar CAS | 762240-92-6 |
| Lambar CAT | Saukewa: RF-PI1193 |
| Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
| Tsarin kwayoyin halitta | C6H7F3N4·HCl |
| Nauyin Kwayoyin Halitta | 228.60 |
| Matsayin narkewa | 236.0 ~ 246.0 ℃ |
| Solubility | Mai narkewa a cikin methanol |
| Alamar | Ruifu Chemical |
| Abu | Ƙayyadaddun bayanai |
| Bayyanar | Fari zuwa Kashe-White Crystalline Foda |
| Gano ta HPLC | Lokacin riƙe samfurin ya yi daidai da ma'aunin tunani |
| Ganewa ta IR | Ya bi |
| Asara akan bushewa | <0.50% |
| Abubuwa masu alaƙa | |
| Duk Wani Rashin Tsabtace Guda Daya | <0.50% |
| Jimlar ƙazanta | <1.00% |
| Karfe masu nauyi | <20ppm |
| Tsarkake / Hanyar Bincike | > 99.0% (HPLC) |
| Matsayin Gwaji | Matsayin Kasuwanci |
| Amfani | Matsakaicin Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
Kunshin: Bottle, Aluminum tsare jakar, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi.
3- (Trifluoromethyl) -5,6,7,8-tetrahydro-[1,2,4]triazolo [4,3-a] pyrazine Hydrochloride (CAS: 762240-92-6) shine matsakaici na Sitagliptin Phosphate Monohydrate ( CAS: 654671-77-9), wanda shine mai hanawa DPP4 mai zaɓi na baka-bioailable wanda aka gano ta hanyar haɓaka nau'ikan inhibitors na β-aminoacid da aka samu DPP4.Yana rage ayyukan DPP4 a cikin ci gaba mai dorewa bayan gudanarwar yau da kullun, yana adana matakan kewayawa na GIP da GLP1 masu zuwa bayan abinci a cikin manyan karatun da na yau da kullun kuma yana rage matakan glucose na jini ba tare da haɓakar hypoglycemia ba.Ana amfani da Sitagliptin Phosphate (STG) don kula da nau'in DM na 2 saboda yana inganta sarrafa glycemic ta hanyar haɓaka matakan hormones na incretin mai aiki, GLP-1 (peptide-1) da GIP (insulinotropic peptide mai dogaro da glucose).FDA ta amince da STG a cikin 2006.
