Tenofovir Alafenamide Hemifumarate TAF CAS 1392275-56-7 API Factory Anti-HIV High Quality
Samar da Kasuwancin Tenofovir Matsakaici masu alaƙa:
Tenofovir CAS: 147127-20-6
Tenofovir Disoproxil Fumarate CAS 202138-50-9
Tenofovir Alafenamide Hemifumarate CAS 1392275-56-7
Chloromethyl isopropyl Carbonate CAS 35180-01-9
Diethyl (p-Toluenesulfonyloxymethyl) phosphonate CAS 31618-90-3
(R)-(+) - Propylene Carbonate CAS 16606-55-6
(R)-9-(2-Hydroxypropyl) adenine CAS 14047-28-0
Diethyl (Hydroxymethyl) phosphonate CAS 3084-40-0
Adenine CAS 73-24-5
Sunan Sinadari | Tenofovir Alafenamide Hemifumarate |
Makamantu | TAF;GS-7340 Hemifumarate |
Lambar CAS | 1392275-56-7 |
Lambar CAT | RF-API91 |
Matsayin Hannun jari | A Hannun jari, Ma'aunin Samfuran Har zuwa Daruruwan Kilogram |
Tsarin kwayoyin halitta | Saukewa: C25H33N6O9P |
Nauyin Kwayoyin Halitta | 592.55 |
Ajiya Zazzabi | An rufe shi a bushe, zafin daki |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Fari zuwa Kusan Farin lu'ulu'u ko Foda Crystalline |
Solubility | Mai narkewa a cikin Dimethylformamide, da Methanol;Mai Soluble a Ruwa da THF;Dan Soluble a cikin Acetonitrile da Insoluble a Dichloromethane da Toluene |
Identification A | Hotunan shayarwar IR yakamata su yi daidai da abin da ake tunani |
Identity B | Lokacin riƙewa na babban kololuwar mafita na samfurin a cikin ƙayyadaddun abun ciki chromatogram ya dace da na bayanin bayani. |
Gano C | Lokacin riƙe Fumaric Acid na babban kololuwa a cikin ƙaddarar abun ciki chromatogram ya dace da kololuwar magana. |
Abubuwan Ruwa (na KF) | ≤1.0% |
Bayyanar Magani | Ainihin babu ɓangarorin bayyane a cikin 2% (w/v) na bayanin Methanol Magani |
Residual Solvent | |
Acetonitrile | ≤410pm |
Ethanol | ≤5000ppm |
Dichloromethane | ≤600ppm |
Toluene | ≤890ppm |
Ragowa akan Ignition | ≤0.10% |
Karfe masu nauyi | ≤20ppm |
Abubuwa masu alaƙa | |
PMPA | ≤1.0% |
Anhydride PMPA | ≤0.75% |
Single Phenyl PMPA | ≤1.0% |
Duk Wani Tsaftar Da Ba A Fayyace Ba | ≤0.15% |
Jimlar ƙazanta | ≤2.0% |
Isomer | ≤1.0% |
Abun ciki na Fumaric Acid | 9.0% ~ 13.0% (a kan anhydrous-akai) |
Iyakar Microbial | |
Jimlar Ƙididdigar Ƙwayoyin Ƙirar Ƙira | ≤1000CFU/g |
Jimillar Yeasts da Molds | ≤100CFU/g |
Escherichia Coli | Babu |
Assay | 98.0% ~ 102.0% (a kan anhydrous da sauran ƙarfi-free tushen) |
Matsayin Gwaji | Matsayin Kasuwanci |
Kunshin: Bottle, Aluminum tsare jakar, Kwali drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.
Tenofovir Alafenamide Hemifumarate (TAF, GS-7340 hemifumarate), CAS 1392275-56-7.Ta hanyar toshe reverse transcriptase, TAF ta hana HIV daga yawaita kuma zai iya rage adadin HIV a jiki.Tenofovir alafenamide magani ne, wanda ke nufin cewa magani ne mara aiki.A cikin jiki, ana canza tenofovir alafenamide zuwa Tenofovir diphosphate (TFV-DP).An amince da Tenofovir Alafenamide Fumarate a cikin Nuwamba 2015 don maganin HIV-1.