Tolvaptan CAS 150683-30-0 API Tsabta > 99.0% (HPLC)
Samar da Samfuran Tolvaptan da Matsakaici masu alaƙa:
Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-daya CAS 160129-45-3
o-Toluoyl Chloride CAS 933-88-0
4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5
Suna | Tolvaptan |
Sunan Sinadari | N-[4- (9-chloro-6-hydroxy-2-azabicyclo[5.4.0]undeca-8,10,12-triene-2-carbonyl)-3-methyl-phenyl]-2-methyl-benzamide |
Lambar CAS | 150683-30-0 |
Lambar CAT | RF-API101 |
Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
Tsarin kwayoyin halitta | Saukewa: C26H25ClN2O3 |
Nauyin Kwayoyin Halitta | 448.94 |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Fari zuwa Kashe-White Crystalline Foda |
Hanyoyin Ganewa | IR, HPLC |
Solubility | Mai narkewa a cikin barasa na Benzyl da methanol amma Ba a iya narkewa a cikin Ruwa da Hexane |
Tsarkake / Hanyar Bincike | > 99.0% (HPLC) |
Matsayin narkewa | 219.0 ~ 222.0 ℃ |
Asara akan bushewa | <0.50% |
Ragowa akan Ignition | <0.10% |
Tsaftace Guda Daya | <0.50% |
Jimlar ƙazanta | <1.00% |
Karfe masu nauyi | ≤20ppm |
Ragowar Magani | Haɗu da ƙayyadaddun bayanai |
Matsayin Gwaji | Matsayin Kasuwanci |
Amfani | API;Matsakaicin Magunguna |
Kunshin: Bottle, Aluminum tsare jakar, 25kg / kwali Drum, ko bisa ga abokin ciniki ta bukata
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi
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Tolvaptan (CAS: 150683-30-0), kuma aka sani da OPC-41061, wani zaɓi ne, mai gasa arginine vasopressin antagonist 2 antagonist da aka yi amfani da shi don magance hyponatremia (ƙananan matakan sodium na jini) wanda ke da alaƙa da gazawar zuciya, cirrhosis, da ciwo na rashin dacewa hormone antidiuretic (SIADH).Otsuka Pharmaceutical lasisi tolvaptan karkashin sunan kasuwanci Samsca bayan FDA ta amince da miyagun ƙwayoyi a watan Mayu 2009. Tolvaptan kuma ya nuna tasiri a kan polycystic koda cuta.A cikin gwaji na 2004, tolvaptan da aka gudanar tare da diuretics na gargajiya an lura da shi don ƙara yawan fitar da ruwa mai yawa da kuma inganta matakan sodium na jini a cikin marasa lafiya da ke fama da ciwon zuciya ba tare da haifar da sakamako masu illa irin su hypotension (ƙananan jini) ko hypokalemia (rage matakan jini na potassium).Har ila yau, miyagun ƙwayoyi bai nuna wani tasiri ba akan aikin koda.