Tranexamic Acid CAS 1197-18-8 Assay 99.0 ~ 101.0% (Titration)
Shanghai Ruifu Chemical Co., Ltd. shine jagoran masana'anta na Tranexamic Acid (CAS: 1197-18-8) tare da inganci.Ruifu Chemical na iya samar da isar da saƙo na duniya, farashi mai gasa, kyakkyawan sabis, ƙanana da adadi mai yawa akwai.Sayi Tranexamic Acid,Please contact: alvin@ruifuchem.com
| Sunan Sinadari | Tranexamic acid |
| Makamantu | trans-4- (Aminomethyl) cyclohexanecarboxylic Acid;trans-Tranexamic acid;TAMCHA;AMCHA;HAKU;AMCA;t-AMCHA;trans-Amcha |
| Matsayin Hannun jari | A Stock, Kasuwancin Kasuwanci |
| Lambar CAS | 1197-18-8 |
| Tsarin kwayoyin halitta | Saukewa: C8H15NO2 |
| Nauyin Kwayoyin Halitta | 157.21 g/mol |
| Matsayin narkewa | > 300 ℃ (lit.) |
| Kwanciyar hankali | Hygroscopic |
| Ruwan Solubility | Mai narkewa a cikin Ruwa, Kusan Gaskiya |
| COA & MSDS | Akwai |
| Misalin Kyauta | Akwai |
| Asalin | Shanghai, China |
| Alamar | Ruifu Chemical |
| Abubuwa | Ƙayyadaddun bayanai | Sakamako |
| Bayyanar | Farin Crystalline Foda | Ya bi |
| Solubility | Mai narkewa a cikin Ruwa da Glacial Acetic Acid, Kusan Ba Mai Soluble a Ethanol da Acetone (96%) | Ya bi |
| IR Spectrum | A cikin Concordance tare da Tranexamic Acid CRS | Ya bi |
| pH | 7.0-8.0 | 7.32 |
| Asara akan bushewa | <0.50% | 0.06% |
| Sulfate ash | <0.10% | 0.02% |
| Karfe masu nauyi (Pb) | ≤10ppm | <10ppm |
| Chloride (Cl) | ≤140ppm | <140pm |
| Arsenic (AS) | ≤2pm | <2pm |
| Assay | 99.0 ~ 101.0% (ta Titration) | 99.84% |
| Abubuwa masu alaƙa | ||
| Najasa A | <0.10% | 0% |
| Rashin tsarki B | <0.20% | 0.0815% |
| Rashin tsarki C | <0.10% | 0.0089% |
| Rashin tsarki D | <0.10% | 0.0063% |
| Jimlar ƙazanta | <0.20% (Sai A,B) | 0.015% |
| Kammalawa | An gwada samfurin kuma ya dace da ƙayyadaddun da aka bayar | |
Kunshin:Fluorinated Bottle, Aluminum tsare jakar, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye akwati sosai kuma a adana a wuri mai sanyi, bushe (2 ~ 8 ℃) da ma'ajin da ke da isasshen iska daga abubuwan da ba su dace ba.Kare daga haske da danshi.
Jirgin ruwa:Isar da shi zuwa duniya ta iska, ta FedEx / DHL Express.Bayar da isarwa cikin sauri kuma abin dogaro.
Tranexamic acid
C8H15NO2 157.2
trans-4- (Aminomethyl) cyclohexanecarboxylic acid;
Cyclohexanecarboxylic acid, 4- (aminomethyl) -, trans [1197-18-8].
BAYANI
Tranexamic acid ya ƙunshi NLT 99.0% da NMT 101.0% na C8H15NO2, ƙididdiga akan busasshen tushe.
GANO
• Shakar Infrared <197K>
ASSAY
• Tsari
Maganin samfurin: 140 MG na Tranexamic Acid a cikin 20 ml na glacial acetic acid
Titrimetric tsarin
(Duba Titrimetry <541>.)
Yanayin: Kai tsaye titration
Titrant: 0.1 N perchloric acid VS
Gano ƙarshen ƙarshen: Potentiometric
Bincike
Misali: Misalin bayani
Titrate tare da 0.1 N perchloric acid VS, ƙayyadaddun ƙarshen ƙarshen da ƙarfi.Gudanar da titration mara kyau.
Kowane ml na 0.1 N perchloric acid yayi daidai da 15.72 MG na C8H15NO2.
Sharuɗɗan karɓa: 99.0% -101.0% akan busasshen tushe
RASHIN ZUCIYA
Najasa Na Inorganic
• Ragowa akan ƙonewa <281>: NMT 0.1%;Ana amfani da samfurin 1-g
• Karfe masu nauyi, Hanyar II <231>: NMT 10 ppm
• Chloride da Sulfate, Chloride <221>: Wani yanki na 0.51-g yana nuna babu chloride fiye da daidai da 0.1 ml na 0.020 N hydrochloric acid (0.014%).
Najasa Na Halitta
• Tsari
Lokacin wayar hannu: Narke 11.0 g na monobasic sodium phosphate anhydrous a cikin 500 ml na ruwa, kuma ƙara 5 ml na triethylamine, sannan 1.4 g na sodium lauryl sulfate ya biyo baya.Daidaita tare da diluted phosphoric acid (10% w / w) zuwa pH na 2.5, kuma tsarma da ruwa zuwa 600 ml.Mix wannan maganin tare da 400 ml na methanol.
Maganin dacewa da tsarin: 0.2 mg/mL na USP Tranexamic Acid RS da 0.002 mg/mL na USP Tranexamic Acid Compound C RS a cikin ruwa
Daidaitaccen bayani: 50 µg/ml na USP Tranexamic Acid RS a cikin ruwa
Maganin samfurin: 10 mg/mL na Tranexamic Acid a cikin ruwa
Tsarin chromatographic
(Duba Chromatography <621>, Dacewar Tsarin.)
Yanayin: LC
Mai ganowa: UV 220 nm
Tushen: 4.6-mm × 25-cm;5-µm shiryarwa L1
Yawan gudu: 1 ml/min
Girman allura: 20µL
Lokacin gudu: sau 3 lokacin riƙe tranexamic acid
Dacewar tsarin
Misali: Maganin dacewa da tsarin
Abubuwan da suka dace
Resolution: NLT 2.0 tsakanin Tranexamic Acid da 0.002 mg/mL na sinadarin tranexamic acid C.
Bincike
Samfurori: Daidaitaccen bayani da Samfurin bayani
Yi ƙididdige yawan ƙazantar kowane mutum a cikin ɓangaren Tranexamic Acid da aka ɗauka:
Sakamako = (rU/rS) × (CS/CU) × (0.1F)
rU = kololuwar amsa ga kowane ƙazanta daga Maganin Samfurin
rS = kololuwar amsa ga tranexamic acid daga daidaitaccen bayani
CS = maida hankali na USP Tranexamic Acid RS a daidaitaccen bayani (µg/ml)
CU = taro na Tranexamic Acid a cikin Samfurin Maganin (mg/mL)
F = Matsayin martani na dangi (duba Shafukan Najasa 1)
Sharuɗɗan karɓa
Najasa ɗaya: Dubi Shafukan Najasa 1.
Jimlar ƙazanta: NMT 0.2%
[Bayyana-Yin kula da kowane kololuwar ƙasa da 0.025%.]
Tebur Najasa 1
Sunan Lokaci Tsayawa Na Dangi Ma'anar Karɓar Ma'anar Amsa, NMT (%)
Abun da ke da alaƙa da Tranexamic acid Aa 2.1 1 0.1
Abun da ke da alaƙa da Tranexamic acid Bb 1.5 1.2 0.2
Abun da ke da alaƙa da Tranexamic acid CC 1.1 0.005 0.1
Tranexamic Acid 1.0 1.0 -
Abun da ke da alaƙa da Tranexamic acid Dd 1.3 0.006 0.1
a trans, trans-4,4 ¢-(Iminodimethylene) di (cyclohexanecarboxylic) acid.
b cis-4- (Aminomethyl) cyclohexanecarboxylic acid.
c (RS) -4- (Aminomethyl) cyclohex-1-enecarbocylic acid.
d 4-Aminomethyl benzoic acid.
MAKAMMAN JARRABAWA
• Asarar bushewa <731>: Dry 1.00 g a 105 a ƙarƙashin injin don 2 h.Yana rasa NMT 0.5% na nauyinsa.
KARIN BUKATA
• Marufi da Ajiye: Ajiye a cikin matsuguni, kuma adana a zafin da bai wuce 30 ba.
• Matsayin Magana na USP <11>
USP Tranexamic Acid RS Danna don Duba Tsarin
USP Tranexamic Acid Abubuwan da ke da alaƙa da C RS
(RS) -4- (Aminomethyl) cyclohex-1-enecarbocylic acid.
C8H13NO2 155
Yadda ake siya?Da fatan za a tuntuɓiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Kwarewar Shekaru 15?Muna da fiye da shekaru 15 na gwaninta a cikin ƙira da fitarwa na matsakaicin matsakaicin magunguna masu inganci ko sinadarai masu kyau.
Manyan Kasuwanni?Sayarwa zuwa kasuwannin cikin gida, Arewacin Amurka, Turai, Indiya, Koriya, Jafananci, Australia, da sauransu.
Fa'idodi?Babban inganci, farashi mai araha, sabis na ƙwararru da tallafin fasaha, bayarwa da sauri.
inganciTabbaci?Tsananin kula da ingancin inganci.Kayan aikin ƙwararru don bincike sun haɗa da NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, gwajin ƙayyadaddun ƙwayoyin cuta, da sauransu.
Misali?Yawancin samfurori suna ba da samfurori kyauta don ƙima mai kyau, farashin jigilar kaya ya kamata a biya ta abokan ciniki.
Binciken Masana'antu?Ma'aikata duba maraba.Da fatan za a yi alƙawari a gaba.
MOQ?Babu MOQ.Karamin tsari abin karɓa ne.
Lokacin Bayarwa? Idan cikin hannun jari, garantin isar da kwana uku.
Sufuri?By Express (FedEx, DHL), ta Air, ta Teku.
Takardu?Bayan sabis na tallace-tallace: COA, MOA, ROS, MSDS, da dai sauransu za a iya ba da su.
Tsarin al'ada?Zai iya ba da sabis na haɗawa na al'ada don dacewa da buƙatun bincikenku.
Sharuɗɗan Biyan kuɗi?Za a fara aiko da daftari na Proforma bayan tabbatar da oda, an rufe bayanan bankin mu.Biya ta T/T (Telex Transfer), PayPal, Western Union, da dai sauransu.
Alamomin haɗari Xi - Haushi
Lambobin haɗari 36/37/38 - Haɗa kai ga idanu, tsarin numfashi da fata.
Bayanin Tsaro
S26 - Idan ana hulɗa da idanu, kurkura nan da nan da ruwa mai yawa kuma ku nemi shawarar likita.
S36 - Sanya tufafin kariya masu dacewa.
S37/39 - Saka safofin hannu masu dacewa da kariya / ido
WGK Jamus 2
Saukewa: RTECS GU840000
Lambar 2922491100
Ajin Hazari MAI GIRMA
Guba LD50 a cikin beraye, beraye (mg/kg): 1500, 1200 iv (Melander)
Tranexamic Acid (CAS: 1197-18-8) sinadari ne na roba na amino acid lysine.Tranexamic acid (wanda aka fi sayar dashi a nau'in kwamfutar hannu kamar Lysteda kuma a cikin nau'i na IV azaman Cyklokapron a Amurka kuma azaman Transamin,Transcam a Asiya, da Espercil a Kudancin Amirka) ana yawan rubutawa don yawan zubar jini.Tranexamic acid wani antifibrinolytic ne wanda ke da gasa ya hana kunna plasminogen zuwa plasmin, kwayoyin da ke da alhakin lalata fibrin.Fibrin shine ainihin tsarin samar da gudan jini a cikin hemostasis. Tranexamic acid yana da kusan sau 8 aikin antifibrinolytic na tsohuwar analog, ε-aminocaproic acid.An fara ba da izini a shekarar 1957 kuma ya sami amincewar Amurka na farko a 1986. Tranexamic Acid Appliciton Ana amfani da shi azaman kayan shafawa Ana amfani da shi sosai a fannin tiyata, likitancin ciki, urology, obstetrics da gynecology, da dai sauransu don magance cututtukan jini daban-daban da sauransu. zubar jinin da ba a saba gani ba yayin tiyata da sauransu. Ana daukarsa a matsayin maganin hemostatic, wanda aka fi amfani da shi don ciwon jini bayan babban tiyata da kuma bayan haihuwa.Tabbas, hemostasis mai yiwuwa shine mafi ƙarancin dalilin da yasa aka ƙara yawan man goge baki don begen yin tasiri.
Tranexamic Acid (CAS: 1197-18-8)
tiyatar zuciya
Yawanci ana amfani da shi wajen tiyatar zuciya, duka tare da ba tare da wucewar bugun zuciya ba.Yana maye gurbin aprotinin.
Zubar jinin haila
An yi amfani da shi azaman jiyya mara kyau na layin farko na zubar da jini mara aiki, da zubar jini mai nauyi mai alaƙa da fibroids na mahaifa.Wani bincike na baya-bayan nan ya nuna majinyatan da aka yi wa maganin tranexamic acid sun fi kamuwa da thrombosis da necrosis a cikin fibroids, kuma na iya haifar da ciwo da zazzabi.
Tasirin fari
Nazarin asibiti na shekaru sun tabbatar da cewa tranexamic acid na iya tsoma wuri yadda ya kamata da sauri, wanda ke taimakawa wajen nuna cikakkiyar farar fata da haske.Sakamakon cire tabo na tranexamic acid yana kusan sau 50 akan Vitamin C, kuma sau 10 akan AHA.Matsakaicin iyakar amfani shine 2% -3%, kuma a cikin kayan shafawa adadin yana kusa da 0.5%
1. Kyakkyawan kwanciyar hankali
Idan aka kwatanta da kayan aikin farar fata na gargajiya, tranexamic acid yana da tsayin daka mai ƙarfi, juriya na acid da alkali, kuma yanayin zafin jiki ba shi da sauƙi a shafa;Babu kariya mai ɗaukar kaya, babu lalacewar tsarin watsawa, babu ƙara kuzari.
2. Tsarin fata yana da sauƙin sha
Ya dace musamman don walƙiya tabo, fari da daidaita sautin fata gaba ɗaya.Baya ga haskaka tabo, tranexamic acid kuma na iya inganta bayyanar launin fata gaba ɗaya da dusar ƙanƙarar fata na gida.
3. Yana iya disashe baƙaƙen tabo, ɗigon rawaya, alamun kuraje, da sauransu
Baƙar fata suna haifar da lalacewa ta UV da tsufa na fata da sauran dalilai.Clotting acid zai iya hana ayyukan tyrosinase da melanocytes, rage samar da melanin daga basal Layer na epidermis, kuma yana da tasirin cire ja.
4. Babban aminci
Mafi girman maida hankali a cikin kayan shafawa shine 2% ~ 3%.
5. Tasirin fari
Tranexamic acid ya dace da kowane nau'in fata don cire pigmentation, fata fata da rage tabo, kamar: Pigmentation bayan fitowar rana;Wuraren duhu;M fata;kuraje da kumburi;Kulawa bayan tiyata bayan laser, jiyya mai haske.
