Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2 API High Quality
Bayar da Vonoprazan Fumarate da Matsakaicin Mahimmanci
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Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2
| Sunan Sinadari | Vonoprazan Fumarate |
| Makamantu | TAK-438 |
| Lambar CAS | 1260141-27-2;881681-01-2 |
| Lambar CAT | RF-API99 |
| Matsayin Hannun jari | A Hannun jari, Ma'aunin Samfuran Har zuwa Daruruwan Kilogram |
| Tsarin kwayoyin halitta | Saukewa: C21H20FN3O6S |
| Nauyin Kwayoyin Halitta | 461.463 |
| Alamar | Ruifu Chemical |
| Abu | Ƙayyadaddun bayanai |
| Bayyanar | Fari ko Kusan-White Crystalline Foda |
| Bayanan Bayani na 1H-NMR | Daidai da Standard |
| Gano IR | Bakan IR Absorption na ƙirar samfurin tare da ma'aunin tunani |
| Bayanin HPLC | Lokacin riƙewa na samfurin concordant tare da ma'aunin tunani |
| Abubuwan Ruwa | ≤0.50% |
| Ragowa akan Ignition | ≤0.20% |
| Karfe masu nauyi (kamar Pb) | ≤20ppm |
| Abubuwa masu alaƙa | |
| Najasa A | ≤0.20% |
| Rashin tsarki B | ≤0.15% |
| Rashin tsarki C | ≤0.15% |
| Duk Wani Najasa | ≤0.10% |
| Jimlar ƙazanta | ≤1.0% |
| Ragowar Magani | |
| Methanol | ≤0.30% |
| Ethanol | ≤0.50% |
| Ethyl acetate | ≤0.50% |
| Hanyar Assay / Analysis | 98.0% ~ 102.0% (Ta HPLC) |
| Matsayin Gwaji | Matsayin Kasuwanci |
| Amfani | API |
Kunshin: Bottle, Aluminum tsare jakar, Kwali drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi.
Vonoprazan Fumurate (TAK-438) (CAS: 1260141-27-2; 881681-01-2), proton famfo inhibitor (PPI), mai ƙarfi ne kuma mai aiki da bakin magana potassium-gasar acid blocker (P-CAB), tare da antisecretory. aiki.Vonoprazan Fumarate yana hana ayyukan H +, K+-ATPase a cikin microsomes na ciki na porcine tare da IC50 na 19 nM a pH 6.5.Vonoprazan Fumarate (Takecab), wanda Takeda da Otsuka suka gano kuma suka haɓaka, PMDA na Japan sun amince da shi a cikin Disamba 2014. Vonoprazan Fumarate an fi amfani dashi don maganin cututtukan helicobacter pylori, gastroesophageal reflux, peptic ulcer, duodenal miki, esophagitis, ciki. Ulcer da sauran cututtuka masu alaka da ciki.Samfurin yana da ƙarfi, dawwamammen hanawa na fitar da acid na ciki.A kashi na magani, Vonoprazan Fumarate yana da tasiri kadan akan sauran enzymes kuma kadan tasiri a kan ayyukan physiological na jiki.Yana da aminci kuma mafi jurewa.
