1-(1-Benzothiophen-4-yl)piperazine Hydrochloride CAS 913614-18-3 Maʻemaʻe >98.0% (HPLC) Brexpiprazole Intermediate Factory
ʻO Ruifu Chemical Supply Brexpiprazole Intermediates
Brexpiprazole CAS 913611-97-9
7-Hydroxyquinolinone CAS 70500-72-0
4-Bromobenzo[b]thiophene CAS 5118-13-8
1-(1-Benzothiophen-4-yl)piperazine Hydrochloride CAS 913614-18-3
7-(4-Chlorobutoxy)quinolin-2(1H)-hoʻokahi CAS 913613-82-8
4-Chlorobenzo[b]thiophene CAS 66490-33-3
Inoa Kimia | 1-(1-Benzothiophen-4-yl) piperazine Hydrochloride |
Nā huaʻōlelo like | Brexpiprazole Intermediate 2;1-Benzo[b]thien-4-yl-Piperazine Hydrochloride;1-Benzo[b]thien-4-ylpiperazine Monohydrochloride |
Helu CAS | 913614-18-3 |
Helu CAT | RF-PI1034 |
Kūlana Kūʻai | Ma ka waihona, ka mana hana 100MT / makahiki |
ʻĀpana Molekala | C12H15ClN2S |
Kaumaha Molecular | 254.7789 |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Keʻokeʻo a hiki i ka pauda keʻokeʻo |
ʻIkepili | Kūlike ka manawa paʻa o ka laʻana me ka maʻamau kuhikuhi |
Maʻemaʻe / Kaʻina Hanana | >99.0% (HPLC) |
Nalo ma ka maloo | <0.50% |
Wai (KF) | <0.50% |
Koena ma ka Ignition | <0.20% |
Na mea pili | (HPLC) |
ʻO kēlā me kēia haumia kanaka | <0.50% |
Huina paumaele | <1.00% |
Infrared Spectrum | Kūlike i ka hoʻolālā |
Proton NMR Spectrum | Kūlike i ka hoʻolālā |
Kūlana hoʻāʻo | ʻOihana Kūlana |
Hoʻohana | Ka waena o Brexpiprazole (CAS: 913611-97-9) |
Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai
ʻO 1-(1-Benzothiophen-4-yl) piperazine Hydrochloride (CAS: 913614-18-3) he mea waena o Brexpiprazole (CAS: 913611-97-9).ʻO Brexpiprazole kahi ʻano antipsychotic atypical.ʻO ia ka dopamine D2 receptor partial agonist.Ma ke ʻano he modulator hana serotonin-dopamine, hiki ke hoʻohana ʻia no ka mālama ʻana i ka schizophrenia, a no ka lāʻau hoʻohui no ke kaumaha.Hiki iā ia ke hāʻawi i ka maikaʻi a me ka ʻae ʻana ma luna o nā lāʻau lapaʻau adjunctive i hoʻokumu ʻia no ka maʻi depressive maʻi (MDD).Hōʻike ka lāʻau lapaʻau i kahi ʻano lāʻau pharmacological kūʻokoʻa, e hana ana ma ke ʻano he agonist ʻāpana o ka serotonin 5-HT1A a me ka dopamine D2 receptors a ma ke ʻano he antagonist piha o 5-HT2A a me noradrenaline α1B / 2C receptors, me ka subnanomolar binding affinity.ʻO ka lāʻau lapaʻau, i hoʻomohala ʻia e Otsuka a me Lundbeck, ua ʻae ʻia ma 2015 e ka FDA no ka mālama ʻana i ka schizophrenia a ma ke ʻano he lāʻau hoʻohui no ke kaumaha.