1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS 143254-82-4 Irinotecan Hydrochloride Intermediate Maʻemaʻe Kiʻekiʻe
Mea Hana Hana Irinotecan a me nā mea pili i waena:
Irinotecan Hydrochloride CAS: 100286-90-6
Irinotecan Free Base CAS: 97682-44-5
Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4
| Inoa Kimia | 1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride |
| Helu CAS | 143254-82-4 |
| Helu CAT | RF-PI243 |
| Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā tona |
| ʻĀpana Molekala | C11H20Cl2N2O |
| Kaumaha Molecular | 267.2 |
| Brand | ʻO Ruifu Chemical |
| 'ikamu | Nā kikoʻī |
| Ka nana aku | Pada Keʻokeʻo a i ʻole Melemele Māmā |
| Hoʻāʻo | ≥98.0% (HPLC) |
| Nalo ma ka maloo | ≤1.0% |
| Metala Kaumaha | ≤20ppm |
| Kūlana hoʻāʻo | ʻOihana Kūlana |
| Hoʻohana | Ka waena o Irinotecan Hydrochloride (CAS: 100286-90-6) |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO Shanghai Ruifu Chemical Co., Ltd. ka mea hana nui a me ka mea hoʻolako o 1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride (CAS: 143254-82-4) me ke kūlana kiʻekiʻe.He mea waena maʻamau i ka synthesis o Irinotecan Hydrochloride (CAS: 100286-90-6), he DNA Topoisomerase I Inhibitor.
ʻO lrinotecan hydrochloride, he semi-synthetic, wai hoʻoheheʻe ʻia o ka camptothecin agent anticancer potent, ua hoʻokuʻu ʻia ma Iapana no ka mālama ʻana i nā maʻi maʻi ʻāʻī, ovarian, a me ka cervical cancer.Hoʻohana ʻo lrinotecan i kāna hana antitumor ma o ke kāohi ʻana i ka topoisomerase I, he enzyme cellular e pili ana i ka mālama ʻana i ke ʻano topographic o DNA i ke kaʻina o ka unuhi ʻana, transcription, a me ka mitosis.Hoʻopau ʻo lrinotecan i ka de-esterification in vivo e hāʻawi i kahi metabolite ikaika, SN-38, ʻoi aku ka ikaika o 1000 ma mua o ka makua.ʻOiai ʻoi aku ka liʻiliʻi o ka ʻawaʻawa ma mua o ka camptothecin, he helu nui o nā maʻi i nā hoʻokolohua lapaʻau i hōʻike i nā hopena ʻaoʻao o ka leukopenia, ka maʻi paʻi, nauseahromiting, a me ka alopecia.
