1-Methyl-3-Pyrrolidinol CAS 13220-33-2 Maʻemaʻe >98.0% (GC)

E hoʻohui i ka 1,2,4-Butanetriol a me ka waikawa acetic glacial i ka ipu hao, hoʻoulu a wela i kahi 100 ℃, e hoʻohui i ke kinoea hydrogen chloride maloʻo, a hana i ka 90 ~ 110 ℃ no 30h, i ka wā i hoʻomaka ai ka nui o ka hydrogen chloride. ʻike ʻia i loko o ke kinoea huelo, ua nānā ʻia ka hopena o ka hopena a ua hoʻopaʻa ʻia ka hydrogen chloride.Ma hope o ka hoʻoluʻu ʻana, ua hoʻokuʻu ʻia ka mea, holoi ʻia me kahi solution sodium carbonate saturated, a kau ʻia i ka distillation ma lalo o ke kaomi haʻahaʻa, a me 120 a 135 ℃.(12.6 a 13. 3kPa) hakina, I.e., 1,4-Dichloro-2-Butanol mea aila, hua mai 50%~60%.
Hoʻohui ʻia ʻo Cyclization i kahi hopena wai o 1,4-Dichloro-2-Butanol a me Methylamine i ka ipu hao, a hoʻomehana ʻia i 120 ℃.Ma lalo o ka hoʻomehana ʻana, a ua hoʻoulu ʻia ka hopena no 10h.Ma hope o ka hoʻoluʻu ʻana, ua hoʻohui ʻia ka sodium hydroxide paʻa, a ua kānana ʻia ka paʻakai inorganic precipitated.Ua hoʻokaʻawale ʻia ka ʻaila ʻaila a hoʻoheheʻe ʻia i ka distillation, a me ka hapa o 76-85 ℃.(2.1 kPa) i hōʻiliʻili ʻia e lilo i huahana pau.ʻO ka unuhi ʻana o ka papa wai me ka benzene e hāʻawi pū i kahi ʻāpana o 1-Methyl-3-Pyrrolidinol.ʻO ka hua ma kahi o 60%.
3. Nā hana nui:
3.1 Kaʻina hana i hoʻololi ʻia: hoʻomalu i ka manawa pane a ʻike i ka hopena hopena
3.2 Ke kaʻina hana hoʻomāmā o 1,4-Dichloro-2-Butanol: hoʻomalu i ka degere ʻūhā o ka distillation a me ka wela hapa.
3.3 Kaʻina hana Cyclization: hoʻomalu i ka mahana a me ka manawa
3.4 1-Methyl-3-Pyrrolidinol kaʻina hoʻoheheʻe ʻana i ka ʻūhā: e hoʻomalu i ke degere ʻūhā o ka hoʻoheheʻe ʻana a me ka wela hapa.
4. Nā wahi mana maikaʻi:
ʻO ka helu hoʻomalu maikaʻi 1: 1,2,4-Butanetriol raw material quality standard
Helu hoʻomalu maikaʻi 2: Kūlana maikaʻi ka hoʻokele kikowaena no ka hopena cyclization
Manaʻo mana maikaʻi 3: 1,4-Dichloro-2-Butanol kūlana kūlana waena
Helu hoʻomalu maikaʻi 4: 1-Methyl-3-Pyrrolidinol i hoʻopau i ka maʻamau o ka huahana