(1S,2S,3R,5S)-(+)-2,3-Pinanediol CAS 18680-27-8 ee ≥99.0% Maʻemaʻe ≥99.0% Bortezomib Intermediate High Maʻemaʻe
Hoʻolako i nā mea kikowaena pili Bortezomib me ka maʻemaʻe kiʻekiʻe
(1S,2S,3R,5S)-(+)-2,3-Pinanediol CAS 18680-27-8
(1R,2R,3S,5R)-(-)-2,3-Pinanediol CAS 22422-34-0
Bortezomib CAS 179324-69-7
| Inoa Kimia | (1S,2S,3R,5S)-(+)-2,3-Pinanediol |
| Nā huaʻōlelo like | (1S,2S,3R,5S)-2,6,6-Trimethylbicyclo[3.1.1]heptane-2,3-diol |
| Helu CAS | 18680-27-8 |
| Helu CAT | RF-CC290 |
| Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
| ʻĀpana Molekala | C10H18O2 |
| Kaumaha Molecular | 170.25 |
| Ka hikiwawe | Chloroform, Toluene |
| Kūlana Hoʻouna | Hoʻouna ʻia ma lalo o ka wela ambient |
| Brand | Kemika Ruifu |
| 'ikamu | Nā kikoʻī |
| Ka nana aku | Keʻokeʻo i ka pauka hoʻoheheʻe keʻokeʻo |
| Lae hehee | 56.0—59.0 ℃ |
| Nalo ma ka maloo | ≤0.50% |
| Koena ma ka Ignition | ≤0.50% |
| Enantiomeric Excess | ee≥99.0% |
| Maʻemaʻe / Kaʻina Hanana | ≥99.0% (GC) |
| Ka Po'ai Pono [α]20/D | +8.5° a i +9.5° (C=6.5, Toluene) |
| Infrared Spectrum | Kūlike |
| Kūlana hoʻāʻo | Kūlana ʻoihana |
| Hoʻohana | Huina Kiral;Nā Kūwaena Lapaʻau;ʻO Bortezomib Intermediate |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO Shanghai Ruifu Chemical Co., Ltd. ka mea hana nui a me ka mea hoʻolako o (1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS 18680-27-8) me ke kūlana kiʻekiʻe, hoʻohana nui ʻia i ka organik. synthesis, synthesis of pharmaceutical intermediates and fine chemical synthesis.
He kuleana koʻikoʻi ʻo Shanghai Ruifu Chemical Co., Ltd. i ka chiral chemistry, ua paʻa ka hui i ka hana ʻana i nā pūhui chiral.Hoʻomaikaʻi nui ʻia kā mākou huahana e nā mea kūʻai aku.
(1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS 18680-27-8), he mea pono Chiral reagent i hoʻohana ʻia i ka synthesis o homochiral α-hydroxyketones a me ka hoʻonā ʻana o nā esters prolineboronate.He mea mua ia no ka chiral allyl boronate i hoʻohana ʻia i ka hoʻomākaukau ʻana i nā β-hydroxyallylsilanes chiral.
(1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS 18680-27-8) he Intermediate o Bortezomib (CAS 179324-69-7) i ka mālama ʻana i ka Multiple Myeloma.Bortezomib, he ubiquitin proteasome (26S) inhibitor (Ki=0.6 nM), i hoʻokuʻu ʻia ma US ma ke ʻano he lapaʻau no ka myeloma lehulehu.Pono kēia proteasome no ka hoʻohaʻahaʻa proteolytic o ka hapa nui o nā protein cellular a aia i loko o nā cell āpau.Pono ia no ka hoʻomalu ʻana i nā kaʻina hana inflammatory, cell cycle regulation a me ka hōʻike ʻana o ka gene a he pahuhopu hou i ka mālama ʻana i ka maʻi kanesa.
