2-Amino-1-Pyrroline Hydrochloride CAS 7544-75-4 Maʻemaʻe >99.5% (HPLC) Tipiracil Hydrochloride Intermediate Factory
Hoʻolako Mea Hana, Mea Kiʻekiʻe a me nā kumukūʻai hoʻokūkū
Tipiracil Hydrochloride (CAS: 183204-72-0) Nā Kūwaena Pili
6-(Chloromethyl)uracil CAS: 18592-13-7
6-(Hydroxymethyl)uracil CAS: 22126-44-9
2-Amino-1-Pyrroline Hydrochloride CAS 7544-75-4
| Inoa Kimia | 2-Amino-1-Pyrroline Hydrochloride |
| Nā huaʻōlelo like | 3,4-Dihydro-2H-Pyrrol-5-Amine Hydrochloride;2-Aminopyrrolidine HCl |
| Helu CAS | 7544-75-4 |
| Helu CAT | RF-PI1838 |
| Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
| ʻĀpana Molekala | C4H8N2·HCl |
| Kaumaha Molecular | 120.58 |
| Lae hehee | 171.0 a 175.0 ℃ |
| Pilikino | Hygroscopic |
| Brand | Kemika Ruifu |
| 'ikamu | Nā kikoʻī | Nā hualoaʻa |
| Ka nana aku | Pauda keʻokeʻo | Pauda keʻokeʻo |
| Maʻemaʻe / Kaʻina Hanana | >99.5% (HPLC) | 99.8% |
| Nui loa ka haumia hoʻokahi | <0.50% | 0.09% |
| Waiwai (KF) | <0.50% | 0.45% |
| Proton NMR Spectrum | Kūlike i ka hoʻolālā | Kūlike |
| Kūlana hoʻāʻo | Kūlana ʻoihana | |
| Hoʻohana | Waena o Tipiracil Hydrochloride (CAS: 183204-72-0) | |
Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai
ʻO 2-Amino-1-Pyrroline Hydrochloride (CAS: 7544-75-4) he hui heterocyclic organik, hiki ke hoʻohana ʻia ma ke ʻano he lāʻau lapaʻau waena.ʻO 2-Amino-1-Pyrroline Hydrochloride kahi mea waena o Tipiracil Hydrochloride (CAS: 183204-72-0) i ka mālama ʻana i ka maʻi maʻi maʻi Rectal.ʻO Tipiracil Hydrochloride kahi mea hoʻokūkū ikaika a hoʻokūkū o thymidine phosphorylase (TPase) me kahi waiwai IC50 o 35 nM no ka placental TPase kanaka.He koho ia no TPase ma luna o nā enzymes pyrimidine-metabolizing ʻē aʻe (IC50s = >1 mM no UPase, OPRTase, TK, a me DPDase).Kāohi ʻo TPI i ka phosphorolysis a me ka hōʻino ʻana o ka trifluorothymidine, kahi nucleoside cytotoxic, i ka umauma o ke kanaka a me ka colon carcinoma tumor samples.Hoʻonui ka lawelawe waha o TPI (12.5-50 mg / kg) i ka hana anti-tumor o trifluorothymidine i loko o kahi kiʻi AZ-521 ʻōpū maʻi maʻi xenograft model.Ua hoʻohana ʻia nā ʻano hana i loaʻa iā TPI no ka mālama ʻana i ka maʻi maʻi maʻi metastatic colorectal.
