2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5 Remdesivir Intermediate COVID-19
Mea Hana Hana Kalepa Remdesivir a me nā mea pili i waena me ke kūlana kiʻekiʻe
Remdesivir CAS 1809249-37-3
2-Ethyl-1-butanol CAS 97-95-0
Trimethylsilyl Cyanide CAS 7677-24-9
4-Nitrophenol CAS 100-02-7
2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate CAS 1911578-98-7
N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester CAS 1354823-36-1
(S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride CAS 946511-97-3
Remdesivir Metabolite (GS-441524) CAS 1191237-69-0
Remdesivir N-2 Kūwaena CAS 1191237-80-5
2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5
7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine CAS 937046-98-5
Pyrrolo[1,2-F][1,2,4]Triazin-4-Amine CAS 159326-68-8
4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine CAS 1770840-43-1
Inoa Kimia | 2,3,5-Tri-O-benzyl-D-ribonolactone |
Nā huaʻōlelo like | 2,3,5-Tri-O-Benzyl-D-Ribono-1,4-Lactone;ʻO Remdesivir Intermediate |
Helu CAS | 55094-52-5 |
Helu CAT | RF-PI301 |
Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā haneli kilogram |
ʻĀpana Molekala | C26H26O5 |
Kaumaha Molecular | 418.49 |
Lae hehee | 54.0-55.0 ℃ |
Kūlana Waihona | Ka Mahana lumi |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Melemele a keʻokeʻo Paʻa |
Ka hikiwawe | Hiki ke hoʻoheheʻe ʻia i loko o CH2Cl2 a ʻaʻole hiki ke hoʻoheheʻe ʻia i ka H2O |
NMR a me MS | Pono e hoʻokō |
ʻIkepili | IR a me TLC |
Mākū | ≤1.0% |
Koena ma ka Ignition | ≤0.50% |
ʻO kēlā me kēia haumia kanaka | ≤0.50% |
Nā Metala Kaumaha | ≤50ppm |
HPLC (210nm) | ≥99.0% |
HPLC (ELSD) | ≥99.0% |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | Ka waena o Remdesivir (CAS 1809249-37-3) |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO 2,3,5-Tri-O-benzyl-D-ribonolactone (CAS 55094-52-5) kahi mea waena Remdesivir.ʻO Remdesivir (CAS 1809249-37-3) kahi lāʻau antiviral hou i ka papa o nā analog nucleotide, i hoʻohana ʻia i ka mālama ʻana i ka COVID-19.ʻO Remdesivir (GS-5734) kahi analogue antiviral nucleoside hou e kāohi ana i ka murine hepatitis virus (MHV) me EC50 like me SARS-CoV a me MERS-CoV.ʻO nā Coronaviruses (CoVs) he mau maʻi virus RNA i hoʻopaʻa ʻia e hoʻopā i nā ʻano holoholona.I loko o ke kanaka, ua ʻike ʻia nā CoVs ma ke ʻano he kumu maʻamau i ke anu a me ka maʻi pneumonia a hiki i ka puka ʻana mai o ka maʻi maʻi maʻi hanu nui (SARS-CoV) i 2002 a me Middle East respiratory syndrome coronavirus (MERS-CoV) i 2012 mai nā kumu zoonotic.ʻO Remdesivir ka monophosphoramidate prodrug o ka C-adenosine nucleoside analogue GS-441524.I loko o nā pūnaewele lolo loloa (DBT) i hoʻopili ʻia me MHV, ua ʻoi aku ka ikaika o ka GS-5734 i ka MHV ma mua o GS-441524, me ka GS-5734 EC50 o 0.03 M. Eia kekahi, ua hoʻoholo ʻia nā waiwai EC50 ma hope o ka mālama ʻana me GS-441524 a me GS-441524. i loko o nā moʻomeheu epithelial cell (HAE) i hoʻopili ʻia e SARS-CoV- a me MERS-CoV.