2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0 Maʻemaʻe ≥99.5% (GC) Sitagliptin Phosphate Monohydrate Intermediate
Hoʻolako i nā mea kikowaena pili i ka Sitagliptin Phosphate Monohydrate:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3
Inoa Kimia | 2,4,5-Trifluorophenylacetic Acid |
Helu CAS | 209995-38-0 |
Helu CAT | RF-PI1191 |
Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā tona |
ʻĀpana Molekala | C8H5F3O2 |
Kaumaha Molecular | 190.12 |
Lae hehee | 121.0 a 125.0 ℃ |
Ka hoʻoheheʻe | Hiki ke hoʻoheheʻe ʻia i ka Methanol |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Keʻokeʻo a hiki i ka pauda keʻokeʻo |
Maʻemaʻe / Kaʻina Hanana | ≥99.5% (GC) |
Māmā (KF) | ≤0.50% |
Koena ma ka Igniton | ≤0.50% |
Huina paumaele | ≤0.50% |
Kūlana hoʻāʻo | ʻOihana Kūlana |
Hoʻohana | Ka waena o Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai.
ʻO 2,4,5-Trifluorophenylacetic Acid (CAS: 209995-38-0) kahi mea waena o Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9).Hoʻohana ʻia ʻo Sitagliptin Phosphate (STG) e mālama i ka DM type 2 no ka mea e hoʻomaikaʻi i ka mana glycemic ma o ka hoʻonui ʻana i nā pae o nā hormones incretin ikaika, GLP-1 (peptide-1) a me GIP (glucose-dependent insulinotropic peptide).ʻO ka hoʻoulu ʻana o kēia mau incretins i loko o nā pūnaewele β-pancreatic e hoʻonui ai i nā pae o ka cyclic adenosine monophosphate (cAMP) a me ka calcium intracellular, me ka huna ʻana o ka insulin i hilinaʻi i ka glucose (2).Aia kēia lāʻau hypoglycemic i kahi papa hou i kapa ʻia ʻo dipeptidyl peptidase IV inhibitors.Ua ʻae ʻia ʻo STG e ka FDA i ka makahiki 2006.