(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8 Atazanavir Intermediate High Clean
Mea Hana Mea Hoolako Atazanavir Piliwaena
Moc-L-Tert-Leucine CAS 162537-11-3
4-(2-Pyridyl)benzaldehyde CAS 127406-56-8
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate CAS 198904-85-7
Atazanavir CAS 198904-31-3
Atazanavir Sulfate CAS 229975-97-7
Kūlana Kiʻekiʻe, Hana Kūʻai
Inoa Kimia | (2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane |
Nā huaʻōlelo like | (2R,3S)-3-(tert-Boc)amino-1,2-epoxy-4-phenylbutane;(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane;Atazanavir Intermediate;Atazanavir Impurity C;threo-N-Boc-L-phenylalanine epoxide |
Helu CAS | 98760-08-8 |
Helu CAT | RF-PI288 |
Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā tona |
ʻĀpana Molekala | C15H21NO3 |
Kaumaha Molecular | 263.34 |
Kūlana Hoʻouna | Ma lalo o ka wela ambient |
Brand | ʻO Ruifu Chemical |
'ikamu | Nā kikoʻī |
Ka nana aku | Keʻokeʻo a i ka pauka kristal keʻokeʻo |
ʻIkepili | Hoʻopaʻa ʻia ka ʻike e HPLC RT |
Ka hoʻoheheʻe | Hiki ke hoʻoheheʻe ʻia i ka Methanol |
Hoʻololi kikoʻī | -10°~ -20° |
Wai (KF) | ≤0.50% |
Koena ma ka Ignition | ≤0.20% |
Na mea pili | |
haumia (RRT0.97) | ≤0.30% |
ʻO kēlā me kēia haumia hoʻokahi | ≤0.30% |
Huina paumaele | ≤1.0% |
Metala Kaumaha | ≤20ppm |
Maʻemaʻe / Kaʻina Hanana | ≥99.0% (HPLC) |
Maʻemaʻe Enantiomeric | ≤0.30% |
Kūlana hoʻāʻo | ʻOihana Kūlana |
Hoʻohana | Ka waena o Atazanavir (CAS 198904-31-3) HIV-1 Protease Inhibitor |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO Shanghai Ruifu Chemical Co., Ltd. ka mea hana nui a me ka mea hoʻolako o (2R,3S) -1,2-Epoxy-3-(Boc-Amino) -4-Phenylbutane (CAS 98760-08-8) me ke kūlana kiʻekiʻe, he mea waena o Atazanavir (CAS 198904-31-3) a me Atazanavir Sulfate (CAS 229975-97-7).ʻO Atazanavir kahi mea hoʻopaneʻe protease HIV hou (PI).
ʻO Atazanavir kahi mea hoʻopale o ke kanaka immunodeficiency virus type 1 (HIV-1) protease, he enzyme e pono ai no ka hana ʻana o Gag a me Gag-Pol polyproteins i loko o nā protein a me nā enzymatic e pono ai no ka hoʻopiʻi hou ʻana.Loaʻa iā ia ke kumu pharmacophore like me nā ʻeono ʻē aʻe i kūʻai nui ʻia i ka HIV protease inhibitors, ʻo ka hapa nui o ia mau mea i hoʻokumu ʻia ma luna o kahi template hydroxyethylamine.Maikaʻi, loaʻa iā ia kahi kumu aza-peptide akā mālama ʻia nā mea pharmacophore like like me nā lipophilic moieties e pili ana i nā kūlana S2, S1, S′1, a me S′2.