(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2 Darunavir Intermediate High Purity
Hāʻawi ka mea hana iā Darunavir i nā huahana pili:
Darunavir CAS 206361-99-1
Darunavir Ethanolate CAS 635728-49-3
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
(3S)-3-(tert-Butoxycarbonyl)amino-1-Chloro-4-Phenyl-2-Butanone CAS 102123-74-0
| Inoa Kimia | (2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane |
| Nā huaʻōlelo like | (2S,3S)-3-(Boc-Amino)-1,2-Epoxy-4-Phenylbutane;(2S,3S)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane;ʻO Darunavir Intermediate |
| Helu CAS | 98737-29-2 |
| Helu CAT | RF-PI286 |
| Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
| ʻĀpana Molekala | C15H21NO3 |
| Kaumaha Molecular | 263.33 |
| Ka hikiwawe | ʻAʻole hiki ke hoʻonā i ka wai.Hiki ke hoʻoheheʻe ʻia i loko o ka Methanol, Chloroform |
| Kūlana Hoʻouna | Hoʻouna ʻia ma lalo o ka wela ambient |
| Brand | Kemika Ruifu |
| 'ikamu | Nā kikoʻī |
| Ka nana aku | Keʻokeʻo a i ka pauka kristal keʻokeʻo |
| ʻIkepili (HPLC) | Hoʻopaʻa ʻia ka ʻike e HPLC |
| Lae hehee | 123.0~128.0 ℃ |
| Māmā (KF) | ≤0.50% |
| Koena ma ka Ignition | ≤0.20% |
| Maʻemaʻe / Kaʻina Hanana | ≥99.0% (HPLC) |
| Chlorohydrin (HPLC) | ≤0.20% |
| Chloromethyl Ketone | ≤0.10% |
| ʻO nā mea haumia hoʻokahi | ≤0.20% |
| Huina paumaele | ≤1.0% |
| Ka haumia ʻo Chiral | ≤0.30% |
| Nā Metala Kaumaha | ≤20ppm |
| Kūlana hoʻāʻo | Kūlana ʻoihana |
| Hoʻohana | Ka waena o Darunavir (CAS 206361-99-1) HIV-1 Protease Inhibitor |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO Shanghai Ruifu Chemical Co., Ltd. ka mea hana nui a me ka mea hoʻolako o (2S,3S) -1,2-Epoxy-3-(Boc-Amino) -4-Phenylbutane (CAS: 98737-29-2) me ke kūlana kiʻekiʻe , he mea waena maʻamau i ka synthesis o Darunavir (CAS 206361-99-1) a me Darunavir Ethanolate (CAS 635728-49-3).
ʻO Darunavir (CAS 206361-99-1) kahi ʻano hou o ka non peptide anti retroviral protease inhibitors i ka maʻi AIDS.Hoʻokumu mua ʻia e ka lālā ʻo Johnson pharmaceutical Iceland, Tibotec.ʻO ia ka bioavailability kiʻekiʻe loa i ka 6 protease inhibitors (saquinavir, ritonavirvir, indinavir, naphthalene nelfinavir, amprenavir a me ABT378/r).Hana ia ma ka pale ʻana i ka hoʻokumu ʻia ʻana o nā mea maʻi virus hou a oʻo mai ka ʻili o nā pūnaewele hoʻokipa i hoʻopili ʻia a kāohi i ka protease o ka maʻi.Ke hoʻohana ʻia ka huahana no ka manawa lōʻihi, hiki iā ia ke hōʻemi i ka vector virus HIV i ke koko, hoʻonui i ka helu o nā cell CD4, hoʻemi i ka manawa o ka maʻi HIV, hoʻomaikaʻi i ka maikaʻi o ke ola a hoʻolōʻihi i ke ola.He kūpono ia no nā mākua i loaʻa i ka maʻi HIV akā ʻaʻohe hopena i ka hoʻohana ʻana i nā lāʻau antiretroviral i loaʻa.Pono e hui pū ʻia ka lāʻau lapaʻau me ka hoʻohana ʻana i nā haʻahaʻa haʻahaʻa o ritonavir a i ʻole nā mea antiretroviral ʻē aʻe, i mea e hoʻomaikaʻi ai i ka pono.
