3-Nitrophthalic Anhydride CAS 641-70-3 Pomalidomide Maʻemaʻe Kūwaena >98.0% (HPLC)
ʻO Ruifu Chemical ka mea hana nui o 3-Nitrophthalic Anhydride (CAS: 641-70-3) me ke kūlana kiʻekiʻe, waena o Pomalidomide (CAS: 19171-19-8).Hiki iā Ruifu Chemical ke hāʻawi aku i ka honua holoʻokoʻa, ke kumukūʻai hoʻokūkū, ka lawelawe maikaʻi loa, ka liʻiliʻi a me ka nui nui i loaʻa.Kūʻai 3-Nitrophthalic Anhydride,Please contact: alvin@ruifuchem.com
| Inoa Kimia | 3-Nitrophthalic Anhydride |
| Nā huaʻōlelo like | 3-Nitrophthalic Acid Anhydride;4-Nitro-2-Benzofuran-1,3-Dione;4-Nitroisobenzofuran-1,3-Dione;4-Nitro-1,3-isobenzofurandione;Pomalidomide haumia A |
| Kūlana Kūʻai | Ma ke Kahua, Hana Hana Kūʻai |
| Helu CAS | 641-70-3 |
| ʻĀpana Molekala | C8H3NO5 |
| Kaumaha Molecular | 193.11 g/mol |
| Lae hehee | 161.0 a 165.0 ℃ |
| Pilikino | ʻAiʻoniʻoni |
| Hiki i ka wai | Hiki ke Decompose i ka wai |
| COA & MSDS | Loaʻa |
| Ke kumu | Shanghai, Kina |
| Brand | Kemika Ruifu |
| Nā mea | Nā Kūlana Nānā | Nā hualoaʻa |
| Ka nana aku | Melemele Māmā i ka Mele Melemele Crystal a i ʻole Crystalline Powder | Hoʻokō |
| Lae hehee | 161.0~165.0 ℃ | 163.0~165.0 ℃ |
| Nalo ma ka maloo | <0.50% | 0.10% |
| Maʻemaʻe / Kaʻina Hanana | >98.0% (HPLC) | 98.85% |
| Infrared Spectrum | Kūlike me ka Hoʻolālā | Hoʻokō |
| 1H NMR Spectrum | Kūlike me ka Hoʻolālā | Hoʻokō |
| Ka hopena | Ua hoʻāʻo ʻia ka huahana a hoʻokō me nā kikoʻī i hāʻawi ʻia | |
| Palapala noi | Ka waena o Pomalidomide (CAS: 19171-19-8) | |
Pūʻolo:ʻO ka ʻōmole Fluorinated, ʻeke ʻeke alumini, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:Paʻi ea.E hoʻopaʻa paʻa i ka pahu a mālama i loko o kahi hale kūʻai maloʻo a me ka makani maikaʻi mai nā mea like ʻole.E mālama i ka lā;pale i ke ahi;pale i ka wai.E hoʻokaʻawale i nā mea oxidizing.
Hoʻouna:Hāʻawi i ka honua ma ka lewa, e FedEx / DHL Express.Hāʻawi wikiwiki a hilinaʻi hoʻi.
Pehea e kūʻai ai?E ʻoluʻolu e kelepona maiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 mau makahiki ʻike?Loaʻa iā mākou ma mua o 15 mau makahiki o ka ʻike i ka hana ʻana a me ka hoʻokuʻu ʻana aku i kahi ākea ākea o nā intermediates pharmaceutical kiʻekiʻe a i ʻole nā kemika maikaʻi.
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Nā pono?ʻO ke kūlana kiʻekiʻe, ke kumukūʻai kūpono, nā lawelawe ʻoihana a me ke kākoʻo ʻenehana, ka lawe wikiwiki ʻana.
ʻAno maikaʻiHōʻoiaʻiʻo?Pūnaehana hoʻomalu maikaʻi koʻikoʻi.ʻO nā lako ʻoihana no ka nānā ʻana ʻo NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Nā laʻana?Hāʻawi ka hapa nui o nā huahana i nā laʻana manuahi no ka loiloi maikaʻi, pono e uku ʻia ke kumukūʻai e nā mea kūʻai aku.
Hooia Hale Hana?Welina mai ka loiloi hale hana.E ʻoluʻolu e hoʻopaʻa manawa ma mua.
MOQ?ʻAʻohe MOQ.ʻAe ʻia ke kauoha liʻiliʻi.
Manawa Hoʻouna? Inā i loko o ka waihona, ʻekolu lā hoʻouna ʻia.
Kaʻahele?Ma ka Express (FedEx, DHL), ma ka Air, ma ke Kai.
Nā palapala?Ma hope o ka lawelawe kūʻai: COA, MOA, ROS, MSDS, etc.
Hoʻohui Kuʻuna?Hiki ke hāʻawi i nā lawelawe synthesis maʻamau e kūpono i kāu mau pono noiʻi.
Kūkākūkā uku?E hoʻouna mua ʻia ka invoice Proforma ma hope o ka hōʻoia ʻana o ke kauoha, hoʻopili ʻia kā mākou ʻike panakō.Uku e T/T (Telex Transfer), PayPal, Western Union, etc.
Nā hōʻailona pōʻino Xi - Hoʻonāukiuki
Nā Code Risk
36/37/38 - E hoʻonāukiuki i ka maka, ka hanu a me ka ʻili.
Ka wehewehe palekana
S26 - Inā pili me nā maka, e holoi koke me ka wai nui a e ʻimi i ka ʻōlelo aʻo kino.
S36 - E hoʻohana i nā lole pale kūpono.
S37/39 - E hoʻohana i nā mīkina lima kūpono a me ka pale maka/maka
WGK Kelemānia 3
FLUKA BRAND F CODES 10-21
TSCA ʻAe
HS Code 2917399090
Hoʻohana ʻia ʻo 3-Nitrophthalic Anhydride (CAS: 641-70-3) ma ke ʻano he waena o Pomalidomide (CAS: 19171-19-8).I Pepeluali 2013, ua ʻae ka US FDA i ka Pomalidomide no ka mālama ʻana i ka myeloma lehulehu (MM) i nā poʻe maʻi me ka piʻi ʻana o ka maʻi ma hope o ka loaʻa ʻana o nā lāʻau lapaʻau ʻē aʻe.ʻO ka Pomalidomide kahi analog 4-amino o ka thalidomide me ka hoʻonui ʻana i ka mana a me ka hoʻomaikaʻi ʻana i ka ʻona.Hoʻohana ka Pomalidomide a me ka thalidomide i kā lākou hopena ma o ka modulation o ka pale ʻana, ka pale ʻana i ka angiogenesis, ka hoʻopili ʻana i ka microenvironment iwi / tumor, a me ka pale ʻana i ka protein cereblon.Pomalidomide potently inhibited in vitro proliferation i loko o keʻano o kanaka MM cell laina, IC50 ~ 10 nM, oiai thalidomide hōʻike kokoke ole inhibition a hiki i 100 μM.I loko o ka ʻiole MM tumor models, 50 mg / kg i kēlā me kēia lā o ka pomalidomide i hopena i ka hōʻailona o ka ulu ʻana o ka maʻi maʻi ma hope o 15 mau lā o ka mālama ʻana a me ka regression piha i nā wiki 3-6 me nā mana i mālama ʻia e thalidomide ma ka nui like.Hoʻomākaukau ʻia ka Pomalidomide e ka condensation o 3-Nitrophthalic Anhydride me 3-Aminopiperidine-2,6-Dione i ukali ʻia e ka catalytic hydrogenation o ka hui nitro.
