3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid CAS 61260-15-9 Olaparib Intermediate Factory
Maʻemaʻe Kiʻekiʻe, Hana Kūʻai
ʻO Olaparib a me nā mea pili e pili ana:
Olaparib CAS 763113-22-0
2-Fluoro-5-Formylbenzonitrile CAS 218301-22-5
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)ʻakika benzoic CAS 763114-26-7
1-(Cyclopropylcarbonyl)piperazine Hydrochloride CAS 1021298-67-8
3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid CAS 61260-15-9
| Inoa Kimia | 3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid |
| Nā huaʻōlelo like | Dimethyl 3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonate |
| Helu CAS | 61260-15-9 |
| Helu CAT | RF-PI453 |
| Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā tona |
| ʻĀpana Molekala | C10H11O5P |
| Kaumaha Molecular | 242.17 |
| Brand | ʻO Ruifu Chemical |
| 'ikamu | Nā kikoʻī |
| Ka nana aku | Pauda keʻokeʻo a ʻaneʻane keʻokeʻo |
| Maemae | ≥98.0% |
| Māmā (KF) | ≤0.50% |
| Huina paumaele | ≤2.0% |
| Kūlana hoʻāʻo | ʻOihana Kūlana |
| Hoʻohana | Ka waena o Olaparib (CAS: 763113-22-0) PARP-Inhibitor |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai.
3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid (CAS: 61260-15-9), waena o Olaparib (CAS: 763113-22-0).ʻO Olaparib kahi ʻano o ka poly ADP-ribose polymerase (PARP) inhibitors, me PARP1, PARP2, a me PARP3.Hoʻopili ʻo PARP i kahi hana hoʻoponopono DNA e hana nui ana i ka hoʻoponopono ʻana i ka pōʻino o ka DNA a me ka apoptosis, no laila ke kuhikuhi pono nei ʻo olaparib i ka mīkini hoʻoponopono DNA o ka hoʻoponopono ʻana i ka cell DNA a lawe i nā hopena ma ka hoʻouka ʻana i nā nāwaliwali koʻikoʻi o nā maʻi kanesa e lawe ana i nā mutations i BRCA1 a BRCA2.Ma muli o kēia hana, hiki ke hoʻohana ʻia no ka mālama mālama ʻana i nā maʻi o ka maʻi maʻi ovarian koʻikoʻi i loaʻa i ka maʻi maʻi maʻi maʻi maʻi maʻi (BRCA) mutation a me ka naʻau i ka lāʻau platinum.
