4-[(1-Pyrrolidinylsulfonyl)methyl]aniline CAS 334981-10-1 Maʻemaʻe >99.0% (HPLC) Almotriptan Aniline Precursor Factory
ʻO Ruifu Chemical Supply Almotriptan Malate Intermediates:
Almotriptan Malate CAS 181183-52-8
1-((4-Hydrazinylbenzyl)sulfonyl)pyrrolidine Hydrochloride CAS 334981-11-2
4-[(1-Pyrrolidinylsulfonyl)methyl]aniline CAS 334981-10-1
1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine CAS 340041-91-0
4-Chlorobutyraldehyde Diethyl Acetal CAS 6139-83-9
Inoa Kimia | 4-[(1-Pyrrolidinylsulfonyl)methyl]aniline |
Nā huaʻōlelo like | 1-[(4-Aminobenzyl)sulfonyl]pyrrolidine;Almotriptan Aniline Precursor |
Helu CAS | 334981-10-1 |
Helu CAT | RF-PI1948 |
Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
ʻĀpana Molekala | C11H16N2O2S |
Kaumaha Molecular | 240.32 |
Lae hehee | 170.0 a 176.0 ℃ |
ʻO ka mānoanoa | 1.31 |
Ka hikiwawe | Hiki i ka Toluene |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Keʻokeʻo a hiki i ka ʻeleʻele Melemele Crystalline pauda |
Maʻemaʻe / Kaʻina Hanana | >99.0% (HPLC) |
Nalo ma ka maloo | <0.50% |
Koena ma ka Ignition | <0.50% |
Max Hoʻokahi haumia | <0.50% |
Huina paumaele | <1.00% |
Nā Metala Kaumaha | <20ppm |
Infrared Spectrum | Kūlike i ka hoʻolālā |
NMR | Kūlike i ka hoʻolālā |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | Almotriptan Aniline Precursor |
Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai
4- [(1-Pyrrolidinylsulfonyl)methyl]aniline (CAS: 334981-10-1) he mea waena i ka hoʻomākaukau ʻana o Almotriptan Malate (CAS: 181183-52-8), Almotriptan Aniline Precursor.ʻO Almotriptan Malate kahi ʻano lāʻau triptan hiki ke hoʻohana ʻia no ka mālama ʻana i ka ʻeha o ka migraine.Aia ʻo Almotriptan i kahi ʻāpana lāʻau o nā agonists receptor serotonin koho.Loaʻa i ka Almotriptan kahi pilina kiʻekiʻe a kikoʻī no nā mea hoʻokipa serotonin 5-HT, e alakaʻi hou ana i ka vascoconstriction o ka moku koko lolo a pili i ka hāʻawi hou ʻana i ke kahe koko.Hoʻopau kēia mau hopena i nā hōʻailona ʻeha mai ka hoʻouna ʻia ʻana i ka lolo, a ke kāohi nei i ka hoʻokuʻu ʻana o kekahi mau mea kūlohelohe e hoʻoulu ai i ka ʻeha, nausea a me nā hōʻailona migraine ʻē aʻe.Akā naʻe, ʻaʻole pale ʻo Almotriptan i ka hoʻouka ʻana o ka migraine.ʻO Almotriptan, i kūʻai ʻia ma 2000, loaʻa ka oralbioavailability kiʻekiʻe ma waena o nā triptans āpau.Hoʻopili ʻia ʻo Almotriptan e MAO-A a me CYP3A4, no laila he ʻoi aku ka maikaʻi o ka hopena ʻaoʻao ke hoʻohālikelike ʻia me Sumatriptan.